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© Research
Publication : Optics Express

Compressed sensing-enabled phase-sensitive swept-source optical coherence tomography

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Optics Express - 21 Jan 2019

Yuye Ling, William Meiniel, Rajinder Singh-Moon, Elsa Angelini, Jean-Christophe Olivo-Marin, Christine P Hendon

Link to Pubmed [PMID] – 30696165

Link to DOI – 10.1364/OE.27.000855

Here we present a novel phase-sensitive swept-source optical coherence tomography (PhS-SS-OCT) system. The simultaneously recorded calibration signal, which is commonly used in SS-OCT to stabilize the phase, is randomly sub-sampled during the acquisition, and it is later reconstructed based on the Compressed Sensing (CS) theory. We first mathematically investigated the method, and verified it through computer simulations. We then conducted a vibrational frequency test and a flow velocity measurement in phantoms to demonstrate the system’s capability of handling phase-sensitive tasks. The proposed scheme shows excellent phase stability with greatly discounted data bandwidth compared with conventional procedures. We further showcased the usefulness of the system in biological samples by detecting the blood flow in ex vivo swine left marginal artery. The proposed system is compatible with most of the existing SS-OCT systems and could be a preferred solution for future high-speed phase-sensitive applications.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6410915/pdf/oe-27-2-855.pdf