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Guides
  • 2024
    Cecchini M, Corringer PJ, Changeux JP, The Nicotinic Acetylcholine Receptor and its Pentameric Homologs: Toward an Allosteric Mechanism of Signal Transduction at the Atomic Level., Annu Rev Biochem 2024 Feb; (): .
  • 2023
    Shi S, Lefebvre SN, Peverini L, Cerdan AH, Milán Rodríguez P, Gielen M, Changeux JP, Cecchini M, Corringer PJ, Illumination of a progressive allosteric mechanism mediating the glycine receptor activation., Nat Commun 2023 Feb; 14(1): 795.
  • 2022
    Cerdan AH, Peverini L, Changeux JP, Corringer PJ, Cecchini M, , Lateral fenestrations in the extracellular domain of the glycine receptor contribute to the main chloride permeation pathway., Sci Adv 2022 Oct; 8(41): eadc9340.
  • 2022
    Dhruv Grover, Jen-Yung Chen, Jiayun Xie, Jinfang Li, Jean-Pierre Changeux & Ralph J. Greenspan, Differential mechanisms underlie trace and delay conditioning in Drosophila, Nature 2022, https://doi.org/10.1038/s41586-022-04433-6.
  • 2021
    Zhang CL, Koukouli F, Allegra M, Ortiz C, Kao HL, Maskos U, Changeux JP, Schmidt-Hieber C, Inhibitory control of synaptic signals preceding locomotion in mouse frontal cortex., Cell Rep 2021 Nov; 37(8): 110035.
  • 2021
    de Melo GD, Lazarini F, Larrous F, Feige L, Kornobis E, Levallois S, Marchio A, Kergoat L, Hardy D, Cokelaer T, Pineau P, Lecuit M, Lledo PM, Changeux JP, Bourhy H, , Attenuation of clinical and immunological outcomes during SARS-CoV-2 infection by ivermectin., EMBO Mol Med 2021 Aug; 13(8): e14122.
  • 2021
    Chosidow O, Bernigaud C, Guillemot D, Giraudeau B, Lespine A, Changeux JP, Bourhy H, Lecuit M, Amoura Z, , Ivermectin as a potential treatment for COVID-19?, PLoS Negl Trop Dis 2021 Jun; 15(6): e0009446.
  • 2021
    Changeux JP, Goulas A, Hilgetag CC, , A Connectomic Hypothesis for the Hominization of the Brain., Cereb Cortex 2021 Mar; 31(5): 2425-2449.
  • 2021
    Goulas A, Changeux JP, Wagstyl K, Amunts K, Palomero-Gallagher N, Hilgetag CC, , The natural axis of transmitter receptor distribution in the human cerebral cortex., Proc Natl Acad Sci U S A 2021 01; 118(3): .
  • 2020
    Koukouli F, Changeux JP, , Do Nicotinic Receptors Modulate High-Order Cognitive Processing?, Trends Neurosci 2020 08; 43(8): 550-564.
  • 2020
    Changeux JP, , Golden Anniversary of the Nicotinic Receptor., Neuron 2020 Jul; 107(1): 14-16.
  • 2020
    Changeux JP, Amoura Z, Rey FA, Miyara M, , A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications., C R Biol 2020 Jun; 343(1): 33-39.
  • 2020
    Cerdan AH, Sisquellas M, Pereira G, Barreto Gomes DE, Changeux JP, Cecchini M, , The Glycine Receptor Allosteric Ligands Library (GRALL)., Bioinformatics 2020 06; 36(11): 3379-3384.
  • 2020
    Changeux JP, , Discovery of the First Neurotransmitter Receptor: The Acetylcholine Nicotinic Receptor., Biomolecules 2020 04; 10(4): .
  • 2020
    Mashour GA, Roelfsema P, Changeux JP, Dehaene S, , Conscious Processing and the Global Neuronal Workspace Hypothesis., Neuron 2020 03; 105(5): 776-798.
  • 2020
    Oasa S, Vukojević V, Rigler R, Tsigelny IF, Changeux JP, Terenius L, , A strategy for designing allosteric modulators of transcription factor dimerization., Proc Natl Acad Sci U S A 2020 02; 117(5): 2683-2686.
  • 2020
    Lou HC, Rømer Thomsen K, Changeux JP, , The Molecular Organization of Self-awareness: Paralimbic Dopamine-GABA Interaction., Front Syst Neurosci 2020 ; 14(): 3.
  • 2019
    Wodak SJ, Paci E, Dokholyan NV, Berezovsky IN, Horovitz A, Li J, Hilser VJ, Bahar I, Karanicolas J, Stock G, Hamm P, Stote RH, Eberhardt J, Chebaro Y, Dejaegere A, Cecchini M, Changeux JP, Bolhuis PG, Vreede J, Faccioli P, Orioli S, Ravasio R, Yan L, Brito C, Wyart M, Gkeka P, Rivalta I, Palermo G, McCammon JA, Panecka-Hofman J, Wade RC, Di Pizio A, Niv MY, Nussinov R, Tsai CJ, Jang H, Padhorny D, Kozakov D, McLeish T, , Allostery in Its Many Disguises: From Theory to Applications., Structure 2019 04; 27(4): 566-578.
  • 2018
    Farisco M, Evers K, Changeux JP, Drug Addiction: From Neuroscience to Ethics, Front Psychiatry 2018;9:595.
  • 2018
    Changeux JP, The nicotinic acetylcholine receptor: a typical ‘allosteric machine’, Philos. Trans. R. Soc. Lond., B, Biol. Sci. 2018 06;373(1749).
  • 2018
    Changeux JP, Structural Identification of the Nicotinic Receptor Ion Channel, Trends Neurosci. 2018 02;41(2):67-70.
  • 2017
    Martin NE, Malik S, Calimet N, Changeux JP, Cecchini M, Un-gating and allosteric modulation of a pentameric ligand-gated ion channel captured by molecular dynamics, PLoS Comput. Biol. 2017 Oct;13(10):e1005784.
  • 2017
    Changeux JP, Christopoulos A, Allosteric modulation as a unifying mechanism for receptor function and regulation, Diabetes Obes Metab 2017 09;19 Suppl 1:4-21.
  • 2017
    Evers K, Changeux JP, Response by the authors, EMBO Rep. 2017 Jul;.
  • 2017
    Changeux JP, Climbing Brain Levels of Organisation from Genes to Consciousness, Trends Cogn. Sci. (Regul. Ed.) 2017 03;21(3):168-181.
  • 2016
    Koukouli F, Rooy M, Changeux JP, Maskos U, , Nicotinic receptors in mouse prefrontal cortex modulate ultraslow fluctuations related to conscious processing., Proc Natl Acad Sci U S A 2016 12; 113(51): 14823-14828.
  • 2013
    Sauguet L, Shahsavar A, Poitevin F, Huon C, Menny A, Nemecz À, Haouz A, Changeux JP, Corringer PJ, Delarue M, Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation, Proc. Natl. Acad. Sci. U.S.A. 2014 Jan;111(3):966-71.
  • 2012
    Corringer PJ, Poitevin F, Prevost MS, Sauguet L, Delarue M, Changeux JP, Structure and pharmacology of pentameric receptor channels: from bacteria to brain, Structure 2012 Jun;20(6):941-56.
  • 2011
    Nury H, Van Renterghem C, Weng Y, Tran A, Baaden M, Dufresne V, Changeux JP, Sonner JM, Delarue M, Corringer PJ, X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel, Nature 2011 Jan;469(7330):428-31.
  • 2010
    Nury H, Poitevin F, Van Renterghem C, Changeux JP, Corringer PJ, Delarue M, Baaden M, One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue, Proc. Natl. Acad. Sci. U.S.A. 2010 Apr;107(14):6275-80.
  • 2005
    Taly A, Delarue M, Grutter T, Nilges M, Le Novère N, Corringer PJ, Changeux JP, Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism, Biophys. J. 2005 Jun;88(6):3954-65.
  • 1989
    Barnard DF, Barnard SA, Carter AB, Patterson KG, Yardumian A, Machin SJ, , An evaluation of the Coulter VCS differential counter., Clin Lab Haematol 1989 ; 11(3): 255-66.
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