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2022Released Parasite-Derived Kinases as Novel Targets for Antiparasitic Therapies., Front Cell Infect Microbiol 2022 ; 12(): 825458.
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2021In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition., Eur J Med Chem 2021 Jan; 210(): 112956.
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2021Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion., Front Cell Infect Microbiol 2021 ; 11(): 655700.
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2021Identification of the Host Substratome of Leishmania-Secreted Casein Kinase 1 Using a SILAC-Based Quantitative Mass Spectrometry Assay., Front Cell Dev Biol 2021 ; 9(): 800098.
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2020SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani., J Proteomics 2020 02; 213(): 103617.
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2019Structure, regulation, and (patho-)physiological functions of the stress-induced protein kinase CK1 delta (CSNK1D)., Gene 2019 Oct; 715(): 144005.
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2019The kinase domain of CK1δ can be phosphorylated by Chk1., Biosci Biotechnol Biochem 2019 Sep; 83(9): 1663-1675.
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2019CRISPR in Parasitology: Not Exactly Cut and Dried!, Trends Parasitol 2019 06; 35(6): 409-422.
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2019Leishmania donovani 90 kD Heat Shock Protein – Impact of Phosphosites on Parasite Fitness, Infectivity and Casein Kinase Affinity., Sci Rep 2019 03; 9(1): 5074.
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2017Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit., Biomed Res Int 2017 ; 2017(): 4635605.
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2017The enemy within: Targeting host-parasite interaction for antileishmanial drug discovery., PLoS Negl Trop Dis 2017 Jun; 11(6): e0005480.
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2016Species- and Strain-Specific Adaptation of the HSP70 Super Family in Pathogenic Trypanosomatids., Genome Biol Evol 2016 07; 8(6): 1980-95.
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2016From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity., Antimicrob Agents Chemother 2016 05; 60(5): 2822-33.
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2015A touch of Zen: post-translational regulation of the Leishmania stress response., Cell Microbiol 2015 May; 17(5): 632-8.
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2014Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability., PLoS Pathog 2014 Sep; 10(9): e1004347.
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2014Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses., Mol Microbiol 2014 Jul; 93(1): 146-66.
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2014Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae., PLoS One 2014 ; 9(2): e89399.
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2014Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection., Antimicrob Agents Chemother 2014 ; 58(3): 1501-15.
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2013Enrichment of Leishmania donovani ATP-binding proteins using a staurosporine capture compound., J Proteomics 2013 Jun; 86(): 97-104.
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2012Apoptotic marker expression in the absence of cell death in staurosporine-treated Leishmania donovani., Antimicrob Agents Chemother 2013 Mar; 57(3): 1252-61.
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2012Synthesis and biological evaluation of 2,3-diarylimidazo[1,2-a]pyridines as antileishmanial agents., Eur J Med Chem 2012 Dec; 58(): 543-56.
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2012The crystal structure of the MAP kinase LmaMPK10 from Leishmania major reveals parasite-specific features and regulatory mechanisms., Structure 2012 Oct; 20(10): 1649-60.
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2011Adaptation of a 2D in-gel kinase assay to trace phosphotransferase activities in the human pathogen Leishmania donovani., J Proteomics 2011 Aug; 74(9): 1644-51.
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2010Cyclosporin A treatment of Leishmania donovani reveals stage-specific functions of cyclophilins in parasite proliferation and viability., PLoS Negl Trop Dis 2010 Jun; 4(6): e729.
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2009Ipl1-dependent phosphorylation of Dam1 is reduced by tension applied on kinetochores., J Cell Sci 2009 Dec; 122(Pt 23): 4375-82.
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2008Ectopic expression of AID in a non-B cell line triggers A:T and G:C point mutations in non-replicating episomal vectors., PLoS One 2008 Jan; 3(1): e1480.
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2007Ipl1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores., Genes Dev 2007 May; 21(10): 1163-8.
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2005Global analysis of protein phosphorylation in yeast., Nature 2005 Dec; 438(7068): 679-84.
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2002Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections., Cell 2002 Feb; 108(3): 317-29.
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2000Saccharomyces cerevisiae PAU genes are induced by anaerobiosis., Mol Microbiol 2000 Mar; 35(6): 1421-30.
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2000Examination of the transcriptional specificity of an enological yeast. A pilot experiment on the chromosome-III right arm., Curr Genet 2000 Jan; 37(1): 1-11.
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1999Multiple Ty-mediated chromosomal translocations lead to karyotype changes in a wine strain of Saccharomyces cerevisiae., Mol Gen Genet 1999 Jun; 261(4-5): 841-50.
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1997Membrane potential-generating malate (MleP) and citrate (CitP) transporters of lactic acid bacteria are homologous proteins. Substrate specificity of the 2-hydroxycarboxylate transporter family., J Biol Chem 1997 Jul; 272(29): 18140-6.