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  • 2024
    Wai T, Is mitochondrial morphology important for cellular physiology?, Trends Endocrinol Metab 2024 Oct; 35(10): 854-871.
  • 2024
    Saunders N, Monel B, Cayet N, Archetti L, Moreno H, Jeanne A, Marguier A, Buchrieser J, Wai T, Schwartz O, Fréchin M, Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling., Nat Commun 2024 Jun; 15(1): 4996.
  • 2023
    Patitucci C, Hernández-Camacho JD, Vimont E, Yde S, Cokelaer T, Chaze T, Giai Gianetto Q, Matondo M, Gazi A, Nemazanyy I, Stroud DA, Hock DH, Donnarumma E, Wai T, Mtfp1 ablation enhances mitochondrial respiration and protects against hepatic steatosis., Nat Commun 2023 Dec; 14(1): 8474.
  • 2023
    Pujol C, Lebigot E, Gaignard P, Galai S, Kraoua I, Bault JP, Dard R, Youssef-Turki IB, Omar S, Boutron A, Wai T, Slama A, MPC2 variants disrupt mitochondrial pyruvate metabolism and cause an early-onset mitochondriopathy., Brain 2023 Mar; 146(3): 858-864.
  • 2023
    Elhage R, Kelly M, Goudin N, Megret J, Legrand A, Nemazanyy I, Patitucci C, Quellec V, Wai T, Hamaï A, Ezine S, Mitochondrial dynamics and metabolic regulation control T cell fate in the thymus., Front Immunol 2023 ; 14(): 1270268.
  • 2022
    Donnarumma E, Kohlhaas M, Vimont E, Kornobis E, Chaze T, Gianetto QG, Matondo M, Moya-Nilges M, Maack C, Wai T, , Mitochondrial Fission Process 1 controls inner membrane integrity and protects against heart failure., Nat Commun 2022 Nov; 13(1): 6634.
  • 2022
    Genin EC, Bannwarth S, Ropert B, Lespinasse F, Mauri-Crouzet A, Augé G, Fragaki K, Cochaud C, Donnarumma E, Lacas-Gervais S, Wai T, Paquis-Flucklinger V, CHCHD10 and SLP2 control the stability of the PHB complex: a key factor for motor neuron viability., Brain 2022 Oct; 145(10): 3415-3430.
  • 2021
    Spier A, Connor MG, Steiner T, Carvalho F, Cossart P, Eisenreich W, Wai T, Stavru F, Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling., Cell Rep 2021 Nov; 37(6): 109989.
  • 2021
    Dorison N, Gaignard P, Bayot A, Gelot A, Becker PH, Fourati S, Lebigot E, Charles P, Wai T, Therond P, Slama A, , Mitochondrial dysfunction caused by novel ATAD3A mutations., Mol Genet Metab ; 131(1-2): 107-113.
  • 2021
    Lepelley A, Della Mina E, Van Nieuwenhove E, Waumans L, Fraitag S, Rice GI, Dhir A, Frémond ML, Rodero MP, Seabra L, Carter E, Bodemer C, Buhas D, Callewaert B, de Lonlay P, De Somer L, Dyment DA, Faes F, Grove L, Holden S, Hully M, Kurian MA, McMillan HJ, Suetens K, Tyynismaa H, Chhun S, Wai T, Wouters C, Bader-Meunier B, Crow YJ, , Enhanced cGAS-STING-dependent interferon signaling associated with mutations in ATAD3A., J Exp Med 2021 10; 218(10): .
  • 2021
    Cretin E, Lopes P, Vimont E, Tatsuta T, Langer T, Gazi A, Sachse M, Yu-Wai-Man P, Reynier P, Wai T, , High-throughput screening identifies suppressors of mitochondrial fragmentation in OPA1 fibroblasts., EMBO Mol Med 2021 06; 13(6): e13579.
  • 2021
    Kleele T, Rey T, Winter J, Zaganelli S, Mahecic D, Perreten Lambert H, Ruberto FP, Nemir M, Wai T, Pedrazzini T, Manley S, , Distinct fission signatures predict mitochondrial degradation or biogenesis., Nature 2021 05; 593(7859): 435-439.
  • 2021
    Ng MYW, Wai T, Simonsen A, Quality control of the mitochondrion., Dev Cell 2021 Apr; 56(7): 881-905.
  • 2021
    Lepelley A, Wai T, Crow YJ, , Mitochondrial Nucleic Acid as a Driver of Pathogenic Type I Interferon Induction in Mendelian Disease., Front Immunol 2021 ; 12(): 729763.
  • 2019
    Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T, , Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy., EMBO Mol Med 2019 01; 11(1): .
  • 2017
    Villalba-Orero M, López-Olañeta MM, González-López E, Padrón-Barthe L, Gómez-Salinero JM, García-Prieto J, Wai T, García-Pavía P, Ibáñez B, Jiménez-Borreguero LJ, Lara-Pezzi E, Lung ultrasound as a translational approach for non-invasive assessment of heart failure with reduced or preserved ejection fraction in mice, Cardiovasc. Res. 2017 Aug;113(10):1113-1123.
  • 2016
    Wai T, Saita S, Nolte H, Müller S, König T, Richter-Dennerlein R, Sprenger HG, Madrenas J, Mühlmeister M, Brandt U, Krüger M, Langer T, The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i-AAA protease YME1L, EMBO Rep. 2016 12;17(12):1844-1856.
  • 2016
    Hartmann B, Wai T, Hu H, MacVicar T, Musante L, Fischer-Zirnsak B, Stenzel W, Gräf R, van den Heuvel L, Ropers HH, Wienker TF, Hübner C, Langer T, Kaindl AM, Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation, Elife 2016 08;5.
  • 2016
    Wai T, Langer T, Mitochondrial Dynamics and Metabolic Regulation, Trends Endocrinol. Metab. 2016 Feb;27(2):105-117.
  • 2015
    Wai T, García-Prieto J, Baker MJ, Merkwirth C, Benit P, Rustin P, Rupérez FJ, Barbas C, Ibañez B, Langer T, Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice, Science 2015 Dec;350(6265):aad0116.
  • 2015
    Lagouge M, Mourier A, Lee HJ, Spåhr H, Wai T, Kukat C, Silva Ramos E, Motori E, Busch JD, Siira S, , Kremmer E, Filipovska A, Larsson NG, SLIRP Regulates the Rate of Mitochondrial Protein Synthesis and Protects LRPPRC from Degradation, PLoS Genet. 2015 Aug;11(8):e1005423.
  • 2015
    Mitsopoulos P, Chang YH, Wai T, König T, Dunn SD, Langer T, Madrenas J, Stomatin-like protein 2 is required for in vivo mitochondrial respiratory chain supercomplex formation and optimal cell function, Mol. Cell. Biol. 2015 May;35(10):1838-47.
  • 2015
    Hlynialuk CJ, Ling B, Baker ZN, Cobine PA, Yu LD, Boulet A, Wai T, Hossain A, El Zawily AM, McFie PJ, Stone SJ, Diaz F, Moraes CT, Viswanathan D, Petris MJ, Leary SC, The Mitochondrial Metallochaperone SCO1 Is Required to Sustain Expression of the High-Affinity Copper Transporter CTR1 and Preserve Copper Homeostasis, Cell Rep 2015 Feb;.
  • 2014
    Anand R, Wai T, Baker MJ, Kladt N, Schauss AC, Rugarli E, Langer T, The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission, J. Cell Biol. 2014 Mar;204(6):919-29.
  • 2013
    Potting C, Tatsuta T, König T, Haag M, Wai T, Aaltonen MJ, Langer T, TRIAP1/PRELI complexes prevent apoptosis by mediating intramitochondrial transport of phosphatidic acid, Cell Metab. 2013 Aug;18(2):287-95.
  • 2012
    Freyer C, Cree LM, Mourier A, Stewart JB, Koolmeister C, Milenkovic D, Wai T, Floros VI, Hagström E, Chatzidaki EE, Wiesner RJ, Samuels DC, Larsson NG, Chinnery PF, Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission, Nat. Genet. 2012 Nov;44(11):1282-5.
  • 2010
    Jokinen R, Marttinen P, Sandell HK, Manninen T, Teerenhovi H, Wai T, Teoli D, Loredo-Osti JC, Shoubridge EA, Battersby BJ, Gimap3 regulates tissue-specific mitochondrial DNA segregation, PLoS Genet. 2010 Oct;6(10):e1001161.
  • 2010
    Sasarman F, Brunel-Guitton C, Antonicka H, Wai T, Shoubridge EA, , LRPPRC and SLIRP interact in a ribonucleoprotein complex that regulates posttranscriptional gene expression in mitochondria, Mol. Biol. Cell 2010 Apr;21(8):1315-23.
  • 2010
    Wai T, Ao A, Zhang X, Cyr D, Dufort D, Shoubridge EA, The role of mitochondrial DNA copy number in mammalian fertility, Biol. Reprod. 2010 Jul;83(1):52-62.
  • 2008
    Wai T, Teoli D, Shoubridge EA, The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes, Nat. Genet. 2008 Dec;40(12):1484-8.
  • 2008
    Shoubridge EA, Wai T, Medicine. Sidestepping mutational meltdown, Science 2008 Feb;319(5865):914-5.
  • 2007
    Shoubridge EA, Wai T, Mitochondrial DNA and the mammalian oocyte, Curr. Top. Dev. Biol. 2007;77:87-111.
  • 2006
    Leary SC, Mattman A, Wai T, Koehn DC, Clarke LA, Chan S, Lomax B, Eydoux P, Vallance HD, Shoubridge EA, A hemizygous SCO2 mutation in an early onset rapidly progressive, fatal cardiomyopathy, Mol. Genet. Metab. 2006 Sep-Oct;89(1-2):129-33.
  • 2004
    Lerner-Ellis JP, Dobson CM, Wai T, Watkins D, Tirone JC, Leclerc D, Doré C, Lepage P, Gravel RA, Rosenblatt DS, Mutations in the MMAA gene in patients with the cblA disorder of vitamin B12 metabolism, Hum. Mutat. 2004 Dec;24(6):509-16.
  • 2002
    Dobson CM, Wai T, Leclerc D, Kadir H, Narang M, Lerner-Ellis JP, Hudson TJ, Rosenblatt DS, Gravel RA, Identification of the gene responsible for the cblB complementation group of vitamin B12-dependent methylmalonic aciduria, Hum. Mol. Genet. 2002 Dec;11(26):3361-9.
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