Wei Yu is utilizing next-generation sequencing technology to reveal the role of key repair factors in V(D)J recombination and translocation formation
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Timeline
Projects
Former Teams
CV
2006-2009 Master of Bioinformatics in SUN YAT-SEN UNIVERSITY (CHINA)
2009-2011 Research assistant in ZheJiang University (CHINA)
2011-2014 Ph.D student in Technische Universität Darmstadt (GERMANY)
2014-Now PostDoc in Institut Pasteur
Publications
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2022SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination., Nat Commun 2022 Jun; 13(1): 3707.
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2020Repair of G1 induced DNA double-strand breaks in S-G2/M by alternative NHEJ., Nat Commun 2020 Oct; 11(1): 5239.
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2016Specific Roles of XRCC4 Paralogs PAXX and XLF during V(D)J Recombination, Cell Rep. 2016 Sep 13;16(11):2967-79. doi: 10.1016/j.celrep.2016.08.069. Epub 2016 Sep 2..
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2013UCHL1 Is a Putative Tumor Suppressor in Ovarian Cancer Cells and Contributes to Cisplatin Resistance, J Cancer. 2013; 4(8): 662–670..
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2013Dynamic protein-protein interaction subnetworks of lung cancer in cases with smoking history, Chin J Cancer. 2013 Feb; 32(2): 84–90..
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2012Recurrent targeted genes of hepatitis B virus in the liver cancer genomes identified by a next-generation sequencing-based approach, PLoS Genet 8(12): e1003065. doi:10.1371/journal.pgen.1003065.
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2011Global Analysis of DNA Methylation by Methyl-Capture Sequencing Reveals Epigenetic Control of Cisplatin Resistance in Ovarian Cancer Cell, PLoS One. 2011; 6(12): e29450..
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2011RNA-Seq Analyses Generate Comprehensive Transcriptomic Landscape and Reveal Complex Transcript Patterns in Hepatocellular Carcinoma, PLoS One. 2011; 6(10): e26168..
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2011The SOX2 response program in glioblastoma multiforme: an integrated ChIP-seq, expression microarray, and microRNA analysis, BMC Genomics. 2011; 12: 11..
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2010ChIP-seq and functional analysis of the SOX2 gene in colorectal cancers, OMICS. 2010 Aug;14(4):369-84. doi: 10.1089/omi.2010.0053..
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