I am interested in cell mobility, using an amoeba model called Entamoeba histolytica, a highly mobile intestinal parasite responsible for dysenteric amebiasis in humans.
My activity lies at the interface between biology for cell culture and experiments, microscopy and the analysis of images acquired using the Icy software, developed in our unit.
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2020Zika Virus Inhibits IFN-α Response by Human Plasmacytoid Dendritic Cells and Induces NS1-Dependent Triggering of CD303 (BDCA-2) Signaling, Front Immunol. 2020 Oct 28;11:582061.
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2020A Protocol to Quantify Cellular Morphodynamics: From Cell Labelling to Automatic Image Analysis, Eukaryome Impact on Human Intestine Homeostasis and Mucosal Immunology, 2020.
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2018Morphodynamics of the Actin-Rich Cytoskeleton in Entamoeba histolytica, Front Cell Infect Microbiol. 2018 May 29;8:179.
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2017BioFlow: a non-invasive, image-based method to measure speed, pressure and forces inside living cells, Sci Rep 2017.
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2016Biophysical measurements in 2D and 3D live cell imaging using fluid dynamics and optical flow, 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI), Prague, 2016, pp. 980-983.
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2016Intracellular traffic of the lysine and glutamic acid rich protein KERP1 reveals features of endomembrane organization in Entamoeba histolytica, Cell. Microbiol. 2016 Aug;18(8):1134-52.
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2012Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons, PLoS Pathog. 2012 Dec;8(12):e1003087.
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2009Rac1 inactivation by lethal toxin from Clostridium sordellii modifies focal adhesions upstream of actin depolymerization, Cell Microbiol. 2010 Feb;12(2):217-32.
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2009Generation of high-titer neutralizing antibodies against botulinum toxins A, B, and E by DNA electrotransfer, Infect Immun 77(5):2221-9.
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2008Clostridium perfringens delta toxin is sequence related to beta toxin, NetB, and Staphylococcus pore-forming toxins, but shows functional differences, PLoS One. 2008;3(11):e3764.
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