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© Artur Scherf
Scanning Electron Microscopy of Red Blood Cell infected by Plasmodium falciparum.
Scientific Fields
Diseases
Organisms
Applications
Technique

CV

Education                                   ______________________________________________________________________________

08.2008 – 05.2014     Ph.D. in Cell and Molecular Biology (Univ. of Pennsylvania, USA)

  • Concentration in Genetics and Gene Regulation
  • Advisor: Dr. Shelley L. Berger
  • Thesis Defense: 25 April, 2014
  • Dissertation: “Chromatin compaction and genome reorganization during spermatogenesis in musculus and sporulation in S. cerevisiae
    • Investigated the role of the linker histone in gene transcription and chromatin compaction during sporulation in cerevisiae
    • Established the project addressing chromatin compaction during mammalian spermatogenesis
    • Characterized the bromodomain-containing protein BRD4 during spermatogenesis in musculus and identified a potential link between extra-nuclear features and dramatic chromatin changes in the compacting sperm nucleus

08.2004 – 05.2008        B.S. in Cellular Biology, minor in French (Univ. of Georgia, USA)

  • GPA: 4.0, graduated with highest honors
  • Undergraduate research advisor (2005 – 2008): Dr. Jacek Gaertig
  • Honors thesis: “Katanin plays a role in microtubule dynamics and ciliary assembly in thermophila.”

 

Employment History and Training ______________________________________________________________________________

11.2020 – Present        Chargée de recherche (Institut Pasteur, Paris, France)

  • Assistant Professor within the Biology of Host-Parasite Interactions Unit, led by Dr. Artur Scherf
  • Investigating protein factors involved in the transcription and organization of the var multigene family

10.2014 – 10.2020         Postdoctoral Researcher (Institut Pasteur, Paris, France)

  • Biology of Host-Parasite Interactions Unit, led by Dr. Artur Scherf (CNRS ERL 9195)
  • Project: Transcriptional control of mutually exclusive var gene expression in Plasmodium falciparum
    • Investigated the role of putative var gene DNA regulatory elements with marker-free CRISPR/Cas9 technology
    • Adapted CRISPR/dCas9 immunoprecipitation-mass spectrometry technology to identify protein factors bound to var gene DNA regulatory elements
    • Adapted CRISPR interference

06–08.2015     Biology of Parasitism Course (Marine Biological Laboratories, USA)

  • Led by Drs. Kirk Deitsch and Gary Ward
  • Intensive training in molecular biology of parasite and vector systems

05–08.2014     Postdoctoral Researcher (Univ. of Pennsylvania, USA)

  • Laboratory of Dr. Shelley Berger
  • Project: Investigate the role of BRD4 in mammalian spermatogenesis

06–07.2007    Undergraduate Research Program (New York University, USA)

  • Laboratory of Dr. Jorge Ghiso
  • Research internship studying the biochemical basis of Alzheimer disease

 

Institutional Responsibilities ______________________________________________________________________________

05.2016 – 05.2019        Departmental Postdoc Representative (Institut Pasteur, Paris, France)

  • Responsibilities included social and professional support of postdoctoral researchers and representation of postdoctoral researcher interests to the leadership of the department and to the Institut Pasteur administration.

09.2008 – 04.2014     Biomedical Graduate Student Association (University of Pennsylvania, USA)

  • This student association organized social and professional activities to enrich the lives of graduate students and to further their careers in science. I was the vice chair of finance from May 2011 – May 2014.

 

Teaching Activities               ______________________________________________________________________________

07.2018, 07.2019           Middle East Biology of Parasitism (University of Bern, Switzerland)

  • Lecture on Next Generation Sequencing for PhD students

11.2017, 11.2018              Sorbonne University (Paris, France)

  • Lecture on epigenetics and antigenic variation for MSc2 students in parasitology

09–12.2011                     Teaching Assistant (University of Pennsylvania, USA)

  • Helped to design and teach a graduate epigenetics course (BIOL483), directed by Dr. Doris Wagner

 

Organization of Conferences ______________________________________________________________________________

11.2018              CRISPR in Parasitology Symposium (Institut Pasteur, Paris, France)

  • Two-day international symposium, the goal of which was to share information and advice on how to establish/develop CRISPR techniques in various parasite and insect vector systems.

 

Prizes, Awards, and Fellowships ______________________________________________________________________________

  • 09.2015 – 08.2017          EMBO Long-term Postdoctoral Fellowship
  • 01.2015 – 12.2016            Institut Pasteur Roux-Cantarini Postdoctoral Fellowship
  • 05.2010 – 04.2012         University of Pennsylvania Genetics T32 Training Grant
  • 2012, 2013                       Biomedical Graduate Studies Travel Grant
  • 2008                                Joy P. Williams Science Award (University of Georgia)
  • 2008                                Goldwater Scholar
  • 08.2004 – 05.2008       Honors Program (University of Georgia)
  • 08.2004 – 05.2008       University of Georgia Governor’s and Charter Scholar
  • 08.2004 – 05.2008       Georgia HOPE Scholar

Publications

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