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© Artur Scherf
Scanning Electron Microscopy of Red Blood Cell infected by Plasmodium falciparum.
Scientific Fields
Diseases
Organisms
Applications
Technique

CV

Education _______________________________________________________________

08.2008 – 05.2014        Ph.D. in Cell and Molecular Biology (University of Pennsylvania, Philadelphia, PA, USA)

  • Concentration in Genetics and Gene Regulation
  • Advisor: Dr. Shelley L. Berger
  • Thesis Defense: 25 April, 2014
  • Dissertation: “Chromatin compaction and genome reorganization during spermatogenesis in musculus and sporulation in S. cerevisiae
    • Investigated the role of the linker histone in gene transcription and chromatin compaction during sporulation in cerevisiae
    • Established the project addressing chromatin compaction during mammalian spermatogenesis
    • Characterized the bromodomain-containing protein BRD4 during spermatogenesis in musculus and identified a potential link between extra-nuclear features and dramatic chromatin changes in the compacting sperm nucleus

08.2004 – 05.2008        B.S. in Cellular Biology, minor in French (University of Georgia, Athens, GA, USA)

  • GPA: 4.0, graduated with highest honors
  • Undergraduate research advisor (2005 – 2008): Dr. Jacek Gaertig
  • Honors thesis: “Katanin plays a role in microtubule dynamics and ciliary assembly in thermophila.”

 

Employment History and Training _______________________________________________________________

10.2014 – Present         Postdoctoral Researcher (Institut Pasteur, Paris, France)

  • Laboratory of Dr. Artur Scherf (CNRS ERL 9195)
  • Project: Transcriptional control of mutually exclusive var gene expression in Plasmodium falciparum
    • Investigated the role of putative var gene DNA regulatory elements with marker-free CRISPR/Cas9 technology
    • Adapted CRISPR/dCas9 immunoprecipitation-mass spectrometry technology to identify protein factors bound to var gene DNA regulatory elements
    • Adapted CRISPR interference

06–08.2015     Biology of Parasitism Course (Marine Biological Laboratories Woods Hole, MA, USA)

  • Led by Drs. Kirk Deitsch and Gary Ward
  • Intensive training in molecular biology of parasite and vector systems

05–08.2014     Postdoctoral Researcher (University of Pennsylvania, Philadelphia, PA, USA)

  • Laboratory of Dr. Shelley Berger
  • Project: Investigate the role of BRD4 in mammalian spermatogenesis

06–07.2007     Undergraduate Research Program (New York University, New York, NY, USA)

  • Laboratory of Dr. Jorge Ghiso
  • Research internship studying the biochemical basis of Alzheimer disease

 

Institutional Responsibilities _______________________________________________________________

05.2016 – 05.2019        Departmental Postdoc Representative (Institut Pasteur, Paris, France)

Responsibilities included social and professional support of postdoctoral researchers and representation of postdoctoral researcher interests to the leadership of the department and to the Institut Pasteur administration.

09.2008 – 04.2014        Biomedical Graduate Student Association (University of Pennsylvania, USA)

This student association organized social and professional activities to enrich the lives of graduate students and to further their careers in science. I was the vice chair of finance from May 2011 – May 2014.

 

Teaching Activities

_______________________________________________________________

07.2018, 07.2019                     Middle East Biology of Parasitism (University of Bern, Switzerland)

Lecture on Next Generation Sequencing for PhD students

11.2017, 11.2018                      Sorbonne University (Paris, France)

Lecture on epigenetics and antigenic variation for MSc2 students in parasitology

09–12.2011                               Teaching Assistant (University of Pennsylvania, USA)

Helped to design and teach a graduate epigenetics course (BIOL483), directed by Dr. Doris Wagner

 

Organization of Conferences _______________________________________________________________

11.2018                      CRISPR in Parasitology Symposium (Institut Pasteur, Paris, France)

Two-day international symposium, the goal of which was to share information and advice on how to establish/develop CRISPR techniques in various parasite and insect vector systems.

 

Prizes, Awards, and Fellowships _______________________________________________________________

09.2015 – 08.2017          EMBO Long-term Postdoctoral Fellowship

01.2015 – 12.2016          Institut Pasteur Roux-Cantarini Postdoctoral Fellowship

05.2010 – 04.2012          University of Pennsylvania Genetics T32 Training Grant

2012, 2013                      Biomedical Graduate Studies Travel Grant

2008                                Joy P. Williams Science Award (University of Georgia)

2008                                Goldwater Scholar

08.2004 – 05.2008          Honors Program (University of Georgia)

08.2004 – 05.2008         University of Georgia Governor’s and Charter Scholar

08.2004 – 05.2008         Georgia HOPE Scholar

Publications

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