Search anything and hit enter
  • Teams
  • Members
  • Projects
  • Events
  • Calls
  • Jobs
  • publications
  • Software
  • Tools
  • Network
  • Equipment

A little guide for advanced search:

  • Tip 1. You can use quotes "" to search for an exact expression.
    Example: "cell division"
  • Tip 2. You can use + symbol to restrict results containing all words.
    Example: +cell +stem
  • Tip 3. You can use + and - symbols to force inclusion or exclusion of specific words.
    Example: +cell -stem
e.g. searching for members in projects tagged cancer
Search for
Count
IN
OUT
Content 1
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Clinical Research Assistant
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Content 2
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Clinical Research Assistant
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Search
Go back
Scroll to top
Share
© Adeline Mallet
Nématodes Caenorhabditis elegans en microscopie électronique à balayage.

Projects

CV

CAREER SUMMARY:

I received my BSc degree in Biotechnology from the University of Naples “Federico II” in Italy in 2004, and my Ph.D. from University of Rome “La Sapienza” in 2008. I started to work on RNA silencing phenomena during my graduate study in the laboratory of Dr. Carlo Cogoni, where I discovered how repetitive DNA elements are recognized and silenced by the RNA interference (RNAi) machinery. After completing my Ph.D., I joined the laboratory of Dr. Alla Grishok at Columbia University for my postdoctoral work. In the Grishok laboratory, I studied chromatin- and RNA-mediated epigenetic mechanisms using C. elegans as a model organism. I used high-throughput genomic approaches combined with genetic, biochemical, and molecular biology tools to study the role of chromatin-binding factors and short RNAs in transcriptional regulation during C. elegans development. I am currently a Group Leader at Institute Pasteur in Paris, in the Department of Developmental and Stem Cell Biology. My main interest is to to characterize the role of RNA-based mechanisms of epigenetic inheritance during animal development and upon environmental changes, using C. elegans as an epigenetic model system.

PUBLICATIONS:

  1. Cecere, G.* and Grishok, A. RNA Chromatin Immunoprecipitation (RNA-ChIP) in Caenorhabditis elegans. Bio-protocol 2014, 4(24): e1358. http://www.bio-protocol.org/e1358 *corresponding authors
  2. Cecere G., Hoersch S., O’Keeffe S., Sachidanandam R., Grishok A. Global effects of the CSR-1 RNA interference pathway on transcriptional landscape. Nat Struct Mol Biol, 2014 Apr;21(4):358-65. doi: 10.1038/nsmb.2801. Epub 2014 Mar 30. Comment in Gene expression: RNAi as a global transcriptional activator. Nat Rev Mol Cell Biol. 2014. Epub 2014 Apr 16.
  3. Cecere G. and Grishok A. A nuclear perspective on RNAi pathways in metazoans. Biochim Biophys Acta – Gene Regulatory Mechanisms Special Issues, 2013 December 17. Review.
  4. Cecere G., Hoersch S, Jensen M.B, Dixit S, Grishok A. The ZFP-1(AF10)/DOT-1 Complex Opposes H2B Ubiquitination to Reduce Pol II Transcription. Mol Cell. 2013 June 27; 50(5): 894–907.
  5. Avgousti D.C., Cecere G., Grishok A. The conserved PHD1-PHD2 domain of ZFP-1/AF10 is a discrete functional module essential for viability in C. elegans. Mol Cell Biol. 2013 Mar;33(5):999-1015. Epub 2012 Dec 21.
  6. Cecere G., Zheng G.X.Y., Mansisidor A.R., Klymko K.E. and Grishok A. Promoters Recognized by Forkhead Proteins Exist for Individual 21U-RNAs. Mol Cell. 2012 Sep 14; 47(5):734-45. doi: 10.1016/j.molcel.2012.06.021. Epub 2012 Jul 19. (F1000 Prime Recommendation)
  7. Mansisidor A.R.*, Cecere G.*, Hoersch S., Jensen M.B., Kawli T., Kennedy L.M., Chavez V., Tan M., Lieb J.D. and Grishok A. A Conserved PHD Finger Protein and Endogenous RNAi Modulate Insulin Signaling in C. elegans. PLoS Genet 7(9):2011. doi:10.1371/journal.pgen.1002299 *co-first authors
  8. Cecere G.*, Cogoni C.*. Quelling targets the rDNA locus and functions in rDNA copy number control. BMC Microbiology, 2009 Feb 25;9(1):44. (Highly accessed articles) *co-corresponding authors
  9. Nolan T.*, Cecere G.*, Mancone C., Alonzi T., Tripodi M., Catalanotto C., Cogoni C. The RNA-dependent RNA polymerase essential for post-transcriptional gene silencing in Neurospora crassa interacts with replication protein A. Nucleic Acids Research, 2008 Feb;36(2):532-8. Epub 2007 Nov 29. (F1000 selection) *co-first authors

ORAL COMMUNICATIONS:

  1. Transgenerational Epigenetic Inheritance Workshop. Wiston House, West Sussex, UK. October 4-7, 2015. Title of the talk: Mechanisms of epigenetic inheritance by short RNAs.
  2. 20th International C. elegans Meeting, UCLA, Los Angeles, CA. June 24-28, 2015. Title of the talk: The CSR-1 RNAi pathway promotes germline transcription and defines the chromatin landscape.
  3. 20th Annual Meeting of the RNA Society, Madison, Wisconsin. May 26-31, 2015. Title of the talk: The CSR-1 RNAi pathway promotes germline transcription and defines the chromatin landscape.
  4. Cold Spring Harbor Laboratory Meeting: Regulatory & Non-Coding RNAs. August 26–30, 2014. Title of the talk: The CSR-1 RNAi pathway promotes germline transcription and defines the chromatin landscape.
  5. New York Area Worm Meeting (NYAWM), City University of New York, December 4, 2013. Title of the talk: The CSR-1 RNAi pathway promotes germline transcription and defines the chromatin landscape.
  6. 19th International C. elegans Meeting, UCLA, Los Angeles, CA. June 26 – 30, 2013. Title of the talk: Positive regulation of Pol II transcription by CSR-1 RNAi pathway in C. elegans.
  7. Cold Spring Harbor Laboratory Meeting: Regulatory & Non-Coding RNAs. August 28–September 1, 2012. Title of the talk: Promoters recognized by Forkhead proteins exist for individual 21U-RNAs.
  8. Keystone Symposia: Mechanism and Biology of Silencing. March 20-25, 2011, Monterey, California. Title of the talk: A Conserved Motif Affecting Nucleosome Occupancy is Required for 21U-RNA Production in C. elegans.
  9. Italian Federation of Life Science (FISV) congress. Riva del Garda, September 26-29, 2007. Title of the talk: A link between post-transcriptional gene silencing and DNA replication.

INVITED SPEAKER:

  1. Gurdon Institute, University of Cambridge, UK. September 21, 2015. Title of the talk: Transcriptional and epigenetic regulation by short RNAs.
  2. Institut de Biologie de l’Ecole Normale Supérieure (IBENS). Paris, France. November 4, 2014. Title of the talk: Transcriptional and epigenetic regulation by short RNAs.
  3. Max Plank Institute for Molecular Genetics (MPIMG). Berlin, Germany. September 8, 2014. Title of the talk: Transcriptional and epigenetic regulation by short RNAs.
  4. Columbia Stem Cell Initiative. Columbia University, New York, USA. February 11, 2013. Title of the talk: Dynamic regulation of transcription by chromatin factors during
    C. elegans development.
  5. Department of Genetics and Development Seminar. Columbia University, New York, USA. March 9, 2012. Title of the talk: Genomic and genetic approaches to unraveling piRNAs biogenesis in C. elegans.
  6. New York Accademy of Science (NYAS). RNAi discussion group, symposium on RNA in Stress Response and Longevity Control. May 12, 2009. Title of talk: Endogenous RNAi and Stress Response in C. elegans.
  7. Centre of Excellence for Biology and Molecular Medicine (BEMM). Rome, July 6, 2007. Title of the talk: A link between post-transcriptional gene silencing and DNA replication.

ABSTRACTS:

  1. Cecere G., Hoersch S., O’Keeffe S., Sachidanandam R., Grishok A. The CSR-1 RNAi pathway promotes germline transcription and defines the chromatin landscape. Cold Spring Harbor Laboratory Meeting: Regulatory & Non-Coding RNAs. August 26–August 30, 2014.
  2. Cecere G., Hoersch S., O’Keeffe S., Sachidanandam R., Grishok A. Positive regulation of Pol II transcription by CSR-1 RNAi pathway in C. elegans. Cold Spring Harbor Laboratory Meeting: Mechanisms of Eukaryotic Transcription. August 27–August 31, 2013.
  3. Cecere G., Sachidanandam R., Hoersch S., Grishok A. Positive regulation of Pol II transcription by CSR-1 RNAi pathway in C. elegans. The 19th International C. elegans Meeting, June 22-26, 2013, UCLA, Los Angeles, CA.
  4. Cecere G., Sachidanandam R., Hoersch S., Grishok A. Dynamic Regulation of RNA Polymerase II Transcription by Endogenous RNAi in C. elegans. Keystone Symposia: RNA Silencing (C7) . March 19 – 24, 2013. Whistler, British Columbia Canada. Awarded with Scholarship
  5. Cecere G, Zheng G, Klymko K, Mansisidor A, Grishok A. A Conserved Motif Affecting Nucleosome Occupancy is Required for 21U-RNA Production in C. elegans. The 18th International C. elegans Meeting, June 22-26, 2011, UCLA, Los Angeles, CA.
  6. Cecere G, Anastasiades D, Mansisidor A, Grishok A. Molecular characterization of ZFP-1, a C. elegans ortholog of the human AF10 gene. Keystone Symposia: Dynamics of Eukaryotic Transcription during Development. April 7 – 12, 2010, Big Sky, Montana.
  7. Cecere G, Mansisidor A, Grishok A. Characterization of the expression pattern of ZFP-1, a chromatin factor involved in RNAi. 17th International C. elegans Meeting, June 24-28, 2009, UCLA, Los Angeles, CA.
  8. Cecere G, Nolan T, Chiofalo G, Mancone C, Aloni T, Catalanotto C, Tripodi M, Cogoni C. A link between post-transcriptional gene silencing and DNA replication. D01.01. FISV, Riva del Garda 2007
  9. Turra D, Hermosa R, Zara L, Cecere G, Vinale F, Marra R, Abadi K, Lorito, M. Plant proteinase inhibitors to control phytopathogenic fungi. Journal of Plant Pathology [J. Plant Pathol.]. Vol. 85, no. 4, suppl., p. 301. Dec 2003
  10. Lanzuise S, Ruocco M, Catapano L, Scala V, Ciliento R, Ambrosino P, Woo S, Scala F, Cecere G, Del Sorbo G, Lorito M. ABC transporter genes of Trichoderma spp., and their involvement in biocontrol. Journal of Plant Pathology [J. Plant Pathol.]. Vol. 85, no. 4, suppl., p. 301. Dec 2003
  11. Ruocco M, Lanzuise S, Woo S, Scala F, Cecere G, Catapano L, Marra R, de Wit PJGM, Van den Burg HA, Lorito M. Induction of disease resistance mechanisms by fungal antagonists: Avirulence genes in Trichoderma spp. .Journal of Plant Pathology [J. Plant Pathol.]. Vol. 85, no. 4, suppl., p. 302. Dec 2003

HONORS:

  • 2015 ERC Starting Grant Award
  • 2013 Keystone Symposia Scholarship Award. Keystone Symposia: RNA Silencing. March 19 – 24, 2013. Whistler, British Columbia Canada.
  • 2007     Best PhD thesis, Centre of Excellence for Biology and Molecular Medicine (BEMM). Rome, 6 July 2007.
  • 2004     Doctoral Fellowship, Graduate School of “La Sapienza” University of Rome, Italy, from 2004- 2008.

TEACHING ACTIVITIES:

  • Lecturer (1.5 hours) Module in épigénétique et la signalisation cellulaire. Ecole doctorale, Muséum National d’Histoire Naturelle, Paris. April 7, 2016.
  • Lecturer (3 hours) in M2 Epigentics Module Teaching at Paris Diderot. November 12, 2015.
  • Lecturer (2 hours) in the course “cellular and molecular biology”, B.Sc. Degree in Medicine, University of Rome “La Sapienza”. Title: “The biology dark matter: non-coding RNAs”.
  • Lecturer (2 hours) in the 4th year course “molecular biology”, B.Sc. Degree in Biotechnology, University of Rome “La Sapienza”. Title: “The evolution of small non-coding RNAs”.

Publications