Christian Demeure is an immunologist, who first studied allergies caused by certain parasitic infections, during his doctorate at the University of Marseille-Luminy. He then became interested in the cellular mechanisms of the development of the allergic disease at the University of Montreal (Canada) where he was associated researcher. Back in France, he is now a group leader in the Yersinia Research Unit at Institut Pasteur, which studies the biology of pathogenic Yersinia bacteria, the most famous member of which is Yersinia pestis, the agent of the plague. Christian Demeure is the scientific manager of the development of a new vaccine against the plague. He also studies the origin of the virulence of pathogenic Yersiniae, the influence of genetics on the mammalian host resistance mechanisms to plague and collaborates in the development of diagnostic tools for this disease.
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2023Reply to Barton et al: signatures of natural selection during the Black Death., bioRxiv 2023 Apr; (): .
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2023[The Black Death, natural selection and susceptibility to auto-immune disorders]., Med Sci (Paris) 2023 Apr; 39(4): 331-333.
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2023Yersinia pestis and plague in the 21st century: learning from a distant past, The Biochemist, 2023, 45 (2), pp.1-5. ⟨10.1042/bio_2023_109⟩.
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2022Evolution of immune genes is associated with the Black Death., Nature 2022 Nov; 611(7935): 312-319.
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2022First Description of a Yersinia pseudotuberculosis Clonal Outbreak in France, Confirmed Using a New Core Genome Multilocus Sequence Typing Method., Microbiol Spectr 2022 Jul; (): e0114522.
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2020Short- and long-term humoral immune response against Yersinia pestis in plague patients, Madagascar., BMC Infect Dis 2020 Nov; 20(1): 822.
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2020Human plague: An old scourge that needs new answers., PLoS Negl Trop Dis 2020 Aug; 14(8): e0008251.
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2020Subcutaneous vaccination with a live attenuated Yersinia pseudotuberculosis plague vaccine, Vaccine 2020 Jan;.
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2019Can we make human plague history? A call to action, BMJ Global Health 2019;4:e001984. doi:10.1136/ bmjgh-2019-001984.
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2019Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination, and diagnostics, Genes and Immunity, 2019, 20 (5), pp.357-370. ⟨10.1038/s41435-019-0065-0⟩.
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