Timeline

Christian Demeure
Permanent Researcher
16 Jan 2024
patent

Plague vaccine

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16 Jan 2024
project

Development of a new vaccine against Plague

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16 Jan 2024
team

Immunity against plague and other Yersinioses

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07 Apr 2023
publication

Reply to Barton et al: signatures of natural selection during the Black Death.

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01 Apr 2023
publication

[The Black Death, natural selection and susceptibility to auto-immune disorders].

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01 Apr 2023
publication

Yersinia pestis and plague in the 21st century: learning from a distant past

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01 Nov 2022
publication

Evolution of immune genes is associated with the Black Death.

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06 Jul 2022
publication

First Description of a Yersinia pseudotuberculosis Clonal Outbreak in France, Confirmed Using a New Core Genome Multilocus Sequence Typing Method.

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10 Nov 2020
publication

Short- and long-term humoral immune response against Yersinia pestis in plague patients, Madagascar.

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01 Aug 2020
publication

Human plague: An old scourge that needs new answers.

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18 Jan 2020
publication

Subcutaneous vaccination with a live attenuated Yersinia pseudotuberculosis plague vaccine

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02 Dec 2019
publication

Can we make human plague history? A call to action

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01 May 2019
publication

Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination, and diagnostics

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01 Jan 2019
publication

Yersinia pestis and plague: an updated view on evolution, virulence determinants, immune subversion, vaccination and diagnostics

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19 Nov 2018
publication

Humoral and cellular immune correlates of protection against bubonic plague by a live Yersinia pseudotuberculosis vaccine.

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15 Sep 2017
publication

Enhanced Macrophage M1 Polarization and Resistance to Apoptosis Enable Resistance to Plague

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01 Apr 2016
publication

Oral vaccination against plague using Yersinia pseudotuberculosis

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16 Oct 2015
publication

Complete Protection against Pneumonic and Bubonic Plague after a Single Oral Vaccination

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11 May 2015
team

Yersinia

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29 Jan 2013
publication

Fast and simple detection of Yersinia pestis applicable to field investigation of plague foci

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15 Nov 2012
publication

Resistance to plague of Mus spretus SEG/Pas mice requires the combined action of at least four genetic factors

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14 Feb 2012
publication

An encapsulated Yersinia pseudotuberculosis is a highly efficient vaccine against pneumonic plague

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01 Jan 2012
publication

Live vaccines against Plague and Pseudotuberculosis

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16 Nov 2011
publication

Early systemic bacterial dissemination and a rapid innate immune response characterize genetic resistance to plague of SEG mice

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06 Jul 2010
publication

Delineation and analysis of chromosomal regions specifying Yersinia pestis

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19 Jan 2010
publication

Efficacy of an oral live vaccine for veterinary use against pseudotuberculosis

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27 May 2008
publication

Oral vaccination against bubonic plague using a live avirulent Yersinia pseudotuberculosis strain

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01 Apr 2005
publication

Anopheles mosquito bites activate cutaneous mast cells leading to a local inflammatory response and lymph node hyperplasia

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15 Mar 2003
publication

Mast cell-derived exosomes induce phenotypic and functional maturation of dendritic cells and elicit specific immune responses in vivo

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01 Sep 2001
publication

T Lymphocytes infiltrating various tumour types express the MHC class II ligand lymphocyte activation gene-3 (LAG-3): role of LAG-3/MHC class II interactions in cell-cell contacts

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01 Sep 2001
publication

Bidirectional negative regulation of human T and dendritic cells by CD47 and its cognate receptor signal-regulator protein-alpha: down-regulation of IL-12 responsiveness and inhibition of dendritic cell activation

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01 Aug 2000
publication

Human monocyte-derived dendritic cells induce naive T cell differentiation into T helper cell type 2 (Th2) or Th1/Th2 effectors. Role of stimulator/responder ratio

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15 Feb 2000
publication

CD47 engagement inhibits cytokine production and maturation of human dendritic cells

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01 Apr 1999
publication

Naive human CD4+ T cells are a major source of lymphotoxin alpha

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01 Mar 1999
publication

Lymphocyte activation gene-3, a MHC class II ligand expressed on activated T cells, stimulates TNF-alpha and IL-12 production by monocytes and dendritic cells

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01 Feb 1999
publication

OX40-Mediated cosignal enhances the maturation of naive human CD4+ T cells into high IL-4-producing effectors

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01 Oct 1998
publication

IL-15 promotes IL-12 production by human monocytes via T cell-dependent contact and may contribute to IL-12-mediated IFN-gamma secretion by CD4+ T cells in the absence of TCR ligation

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01 Aug 1998
publication

Maturation of human neonatal CD4+ and CD8+ T lymphocytes into Th1/Th2 effectors

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01 Dec 1997
publication

Prostaglandin E2 primes naive T cells for the production of anti-inflammatory cytokines

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01 May 1997
publication

In vitro maturation of naive human CD4+ T lymphocytes into Th1, Th2 effectors

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01 Dec 1996
publication

Human Th2-like cell clones induce IL-12 production by dendritic cells and may express several cytokine profiles

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31 Oct 1996
publication

Role of interleukin-12 in the maturation of naive human CD4 T cells

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01 May 1996
publication

CD31 (PECAM-1) is a differentiation antigen lost during human CD4 T-cell maturation into Th1 or Th2 effector cells

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01 Dec 1995
publication

Maturation of neonatal human CD4 T cells: III. Role of B7 co-stimulation at priming

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01 Dec 1995
publication

Default development of cloned human naive CD4 T cells into interleukin-4- and interleukin-5- producing effector cells

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01 Sep 1995
publication

Human naive CD4 T cells produce interleukin-4 at priming and acquire a Th2 phenotype upon repetitive stimulations in neutral conditions

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01 Dec 1994
publication

In vitro maturation of neonatal human CD8 T lymphocytes into IL-4- and IL-5-producing cells

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01 Oct 1994
publication

Interleukin 12 exerts a differential effect on the maturation of neonatal and adult human CD45R0- CD4 T cells

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15 May 1994
publication

In vitro maturation of human neonatal CD4 T lymphocytes. II. Cytokines present at priming modulate the development of lymphokine production

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01 Feb 1994
publication

In vitro maturation of human neonatal CD4 T lymphocytes. I. Induction of IL-4-producing cells after long-term culture in the presence of IL-4 plus either IL-2 or IL-12

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01 Oct 1993
publication

Resistance to Schistosoma mansoni in humans: influence of the IgE/IgG4 balance and IgG2 in immunity to reinfection after chemotherapy

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15 Aug 1993
publication

IL-12 induces the production of IFN-gamma by neonatal human CD4 T cells

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01 Jan 1993
publication

Correlation between cell-mediated immunity and degree of infection in subjects living in an endemic area of schistosomiasis

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01 Aug 1992
publication

Strong serum inhibition of specific IgE correlated to competing IgG4, revealed by a new methodology in subjects from a S. mansoni endemic area

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01 Aug 1992
publication

Environmental, genetic and immunological factors in human resistance to Schistosoma mansoni

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01 Nov 1991
publication

Evidence for an association between human resistance to Schistosoma mansoni and high anti-larval IgE levels

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15 Apr 1988
publication

Human resistance to Schistosoma mansoni is associated with IgG reactivity to a 37-kDa larval surface antigen

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01 Nov 1987
publication

Conformational differences of human IgE on hydrophobic and hydrophilic solid phases detected by monoclonal antibodies

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