Chetan Chitnis joined Institut Pasteur in 2014 to set up the Malaria Parasite Biology & Vaccines Unit. His laboratory investigates how malaria parasites invade human erythrocytes and uses these findings to develop new intervention strategies such as malaria vaccines. Dr. Chitnis completed his PhD at the University of California, Berkeley, in 1990 and conducted postdoctoral research on malaria at the US National Institutes of Health. He returned to India in 1995 where he established a laboratory that combined fundamental and translational malaria research. Dr. Chitnis is a Fellow of the Indian National Science Academy and has been a Wellcome Trust Senior Research Fellow and a Howard Hughes International Research Scholar. He is a recipient of the Infosys Prize in Life Sciences and the Bhatnagar Award in Medical Science, two of India’s most prestigious life sciences awards.
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About
Courses
International Institut Pasteur Vaccinology Course edition 2023
This year, the program will be: Module I : Key steps from epidemiology to clinical trials; Module 2 : Update of vaccine development update against major infectious diseases and future challenges; Module 3: An […]
2023-02-06 21:00:00
2023-03-01 18:00:00
Europe/Paris
International Institut Pasteur Vaccinology Course edition 2023
This year, the program will be: Module I : Key steps from epidemiology to clinical trials; Module 2 : Update of vaccine development update against major infectious diseases and future challenges; Module 3: An […]
Malaria MOOC
The MOOC provides an overview of malaria today, from the cellular biology of the parasite to treatments, from immune response to control and elimination strategies. >>Register here << Malaria is an ancient disease that […]
2024-11-05 09:00:00
2025-11-04 19:00:00
Europe/Paris
Malaria MOOC
The MOOC provides an overview of malaria today, from the cellular biology of the parasite to treatments, from immune response to control and elimination strategies. >>Register here << Malaria is an ancient disease that […]
Vaccinology MOOC
This MOOC describes the successes of vaccination in preventing diseases, as well as the remaining challenges in regard of persisting epidemics and new pandemics. Register on : https://www.fun-mooc.fr/en/courses/vaccinology/ Flyer : MOOC_VACCINOLOGY_2024 Vaccines are among the […]
2024-04-02 08:00:00
2024-07-10 23:00:00
Europe/Paris
Vaccinology MOOC
This MOOC describes the successes of vaccination in preventing diseases, as well as the remaining challenges in regard of persisting epidemics and new pandemics. Register on : https://www.fun-mooc.fr/en/courses/vaccinology/ Flyer : MOOC_VACCINOLOGY_2024 Vaccines are among the […]
Projects
Publications
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2024PvDBPII elicits multiple antibody-mediated mechanisms that reduce growth in a Plasmodium vivax challenge trial., NPJ Vaccines 2024 Jan; 9(1): 10.
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2023Unveiling P. vivax invasion pathways in Duffy-negative individuals, Cell Host & Microbe, In press, ⟨10.1016/j.chom.2023.11.007⟩.
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2022Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target., Cell Rep 2022 Jun; 39(11): 110923.
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2020Phosphorylation-Dependent Assembly of a 14-3-3 Mediated Signaling Complex during Red Blood Cell Invasion by Plasmodium falciparum Merozoites., mBio 2020 08; 11(4): .
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2015Phase I Clinical Trial of a Recombinant Blood Stage Vaccine Candidate for Plasmodium falciparum Malaria Based on MSP1 and EBA175, PLoS ONE 2015;10(4):e0117820.
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2014The central role of cAMP in regulating Plasmodium falciparum merozoite invasion of human erythrocytes, PLoS Pathog. 2014 Dec;10(12):e1004520.
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2013Role of calcineurin and actin dynamics in regulated secretion of microneme proteins in Plasmodium falciparum merozoites during erythrocyte invasion, Cell. Microbiol. 2014 Jan;16(1):50-63.
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2013Calcium-dependent permeabilization of erythrocytes by a perforin-like protein during egress of malaria parasites, Nat Commun 2013;4:1736.
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2012Characterization of Plasmodium falciparum calcium-dependent protein kinase 1 (PfCDPK1) and its role in microneme secretion during erythrocyte invasion, J. Biol. Chem. 2013 Jan;288(3):1590-602.
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2011Targeting TLRs expands the antibody repertoire in response to a malaria vaccine, Sci Transl Med 2011 Jul;3(93):93ra69.
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