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  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
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  • Director of Center
  • Director of Department
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Scientific Fields
Diseases
Organisms
Applications
Technique
Date
25
Jun 2019
Time
11:00:00
25 Rue du Dr Roux, Paris, France
Address
Building: Monod
Location
2019-06-25 11:00:00 2019-06-25 12:00:00 Europe/Paris [C3BI Seminar]- Eran Halperin: New computational tools for the analysis of microbiome dynamics High-throughput microbiome analysis has become ubiquitous over the last few years. However, the interpretation of the data is often non-trivial and highly depends on the methodology used for the analysis. I will describe a […] 25 Rue du Dr Roux, Paris, France Rayan Chikhi rayan.chikhi@pasteur.fr

Speakers

Eran Halperin
(UCLA)

About

High-throughput microbiome analysis has become ubiquitous over the last few years. However, the interpretation of the data is often non-trivial and highly depends on the methodology used for the analysis. I will describe a few methods for the analysis of microbiome in contexts that are typical in such analyses. First, I will describe a new method for microbial source tracking, that is, finding the sources of a microbiome sample. I will demonstrate how using the method one can reach very different conclusions (that make more biological sense) than using previous methods. Specifically, I will show examples on the dynamics of gut microbiome in babies, and on the usage of source tracking as a tool for disease diagnosis. Second, I will discuss novel approaches for the analysis of time-series micorbiome data, and here too, I will show how this new approach results in new biological insights, particularly on the dependence of microbiome in the future on the current composition of the microbiome. The talk will be self contained, and I will not assume any expert knowledge in computer science or statistics

Location

Building: Monod
Address: 25 Rue du Dr Roux, Paris, France