Dr. Sadri ZNAIDI is a biochemist (B.Sc., M.Sc. from the University of Sherbrooke, Canada) and molecular biologist (Ph.D., from the University of Montreal, Canada), with expertise in yeast genetics and functional genomics. He is currently an Assistant Professor at Memorial University of Newfoundland, NL, Canada. He is also a Pasteur Network Affiliate, with affiliations at the Pasteur Institutes in Tunis, Tunisia (LR16IPT01) and in Paris, France (Fungal Biology and Pathogenicity). His current work focuses on the implementation of systems biology-oriented approaches to identify and characterize components of the biological circuitry involved in the interaction of Candida species with the host environment.
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Since 2024: Assistant Professor, Memorial University of Newfoundland, Canada
Since 2016: Pasteur Network Affiliate (Tunis, Tunisia; Paris, France)
2010 – 2015: Postdoctoral fellow, Institut Pasteur, Paris, France
2004 – 2010: Ph.D., Molecular Biology, University of Montreal, Canada
2002 – 2004: M.Sc., Biochemistry, Université de Sherbrooke, Canada
1999 – 2002: B.Sc., Biochemistry, Université de Sherbrooke, Canada
Publications
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2025When HSFs bring the heat-mapping the transcriptional circuitries of HSF-type regulators in Candida albicans, MSphere, 2025, 10 (1), pp.e00644-23. ⟨10.1128/msphere.00644-23⟩.
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2024A gain-of-function mutation in zinc cluster transcription factor Rob1 Drives Candida albicans adaptive growth in the cystic fibrosis lung environment., PLoS Pathog 2024 Apr; 20(4): e1012154.
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2022Functional Portrait of Irf1 (Orf19.217), a Regulator of Morphogenesis and Iron Homeostasis in Candida albicans., Front Cell Infect Microbiol 2022 ; 12(): 960884.
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2021Ethylzingerone, a Novel Compound with Antifungal Activity., Antimicrob Agents Chemother 2021 03; 65(4): .
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2021High Frequency of Enterocytozoon bieneusi Genotype WL12 Occurrence among Immunocompromised Patients with Intestinal Microsporidiosis., J Fungi (Basel) 2021 Feb; 7(3): .
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2020A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans., Nat Commun 2020 12; 11(1): 6224.
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2020mSphere of Influence: Decoding Transcriptional Regulatory Networks To Illuminate the Mechanisms of Microbial Pathogenicity., mSphere 2020 01; 5(1): .
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2020Identification and Characterization of Mediators of Fluconazole Tolerance in Candida albicans., Front Microbiol 2020 ; 11(): 591140.
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2019From Genes to Networks: The Regulatory Circuitry Controlling Candida albicans Morphogenesis., Curr Top Microbiol Immunol 2019 ; 422(): 61-99.
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2018A conserved fungal hub protein involved in adhesion and drug resistance in the human pathogen Candida albicans., Cell Surf 2018 Dec; 4(): 10-19.
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