Epigenetics defines when and where genes are expressed. Epigenetic marks are reversible and inheritable, integrate the impact of the environment and provide cellular plasticity. Aberrant epigenetic patterns are involved in tumor formation, maintenance and […]
Physicist and computer scientist by training, I develop quantitative population models of antibiotic resistance, which I calibrate using optimal experimental design. I then exploit them to engineer optimal treatment strategies.
I study the role of stress as a risk factor for the development of neurodegenerative and psychiatric diseases (Alzheimer’s and Parkinson’s diseases, bipolar and major depression disorders and others) and the neurocircuits implicated. One […]
