Ligne de temps
Pascale Pescher
Ingénieur(e) de Recherche
07 mars 2023
publication
Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage.
Lire plus01 janv. 2023
publication
Amphotericin B resistance correlates with increased fitness in vitro and in vivo in Leishmania (Mundinia) martiniquensis.
Lire plus01 mars 2022
publication
Experimental evolution links post-transcriptional regulation to Leishmania fitness gain.
Lire plus10 févr. 2022
project
PTR 425 EvoLeish: Mapping mechanisms of evolutionary adaptation underlying fitness gain in New World L. infantum strains
Lire plus21 déc. 2021
publication
Genome instability drives epistatic adaptation in the human pathogen Leishmania.
Lire plus22 juin 2020
publication
Dynamic imaging reveals surface exposure of virulent Leishmania amastigotes during pyroptosis of infected macrophages.
Lire plus20 févr. 2020
publication
SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani.
Lire plus24 janv. 2019
16 janv. 2019
project
“Modelling and functional analysis of clonal Evolution in Leishmania – possible role of non-coding RNAs and RNA modification”
Lire plus12 avr. 2018
publication
Stage-specific expression of the proline-alanine transporter in the human pathogen Leishmania
Lire plus01 janv. 2018
publication
Reverse Epidemiology: An Experimental Framework to Drive Leishmania Biomarker Discovery in situ by Functional Genetic Screening Using Relevant Animal Models.
Lire plus06 nov. 2017
publication
Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani
Lire plus25 sept. 2017
publication
New insights into experimental visceral leishmaniasis: Real-time in vivo imaging of Leishmania donovani virulence
Lire plus23 mai 2017
publication
Modulation of Aneuploidy in during Adaptation to Different and Environments and Its Impact on Gene Expression
Lire plus16 juin 2016
publication
Phenotypic Characterization of a Leishmania donovani Cyclophilin 40 Null Mutant
Lire plus14 sept. 2015
07 sept. 2015
project
LeiSHield – A new collaborative action to determine prevalence, anticipate emergence and assess urbanization of cutaneous and visceral leishmaniasis in LeishRIIP partner countries
Lire plus11 mai 2015
01 janv. 2014
publication
Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.
Lire plus21 juil. 2011
publication
Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery
Lire plus26 avr. 2011
publication
Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation
Lire plus21 avr. 2011
publication
Imaging host cell-Leishmania interaction dynamics implicates parasite motility, lysosome recruitment, and host cell wounding in the infection process
Lire plus01 nov. 2010
publication
Identification of Leishmania-specific protein phosphorylation sites by LC-ESI-MS/MS and comparative genomics analyses
Lire plus23 juil. 2009
publication
A dynamic map of antigen recognition by CD4 T cells at the site of Leishmania major infection
Lire plus01 juin 2005
publication
In vivo efficiency of targeted norfloxacin against persistent, isoniazid-insensitive, Mycobacterium bovis BCG present in the physiologically hypoxic mouse liver
Lire plus03 janv. 2005
publication
Targeted norfloxacin is active in vivo against persistent Mycobacterium bovis BCG
Lire plus01 oct. 2003
publication
Enhanced cloning efficiency of mouse bone marrow macrophage progenitors correlates with increased content of CSF-1 receptor of their progeny at low oxygen tension
Lire plus01 janv. 2003
publication
Characterization of a putative type IV aminophospholipid transporter P-type ATPase
Lire plus01 nov. 2002
publication
[Preliminary study on isoniazid-epiroprim combination in a tuberculosis murine model]
Lire plus06 avr. 2001
publication
Mixed immune response induced in rodents by two naked DNA genes coding for mycobacterial glycosylated proteins
Lire plus01 janv. 2001
01 nov. 1999
publication
Deglycosylation of the 45/47-kilodalton antigen complex of Mycobacterium tuberculosis decreases its capacity to elicit in vivo or in vitro cellular immune responses
Lire plus16 oct. 1996
publication
Characterization of murine monoclonal antibodies specific for the 45/47 kDa antigen complex (APA) of Mycobacterium tuberculosis, M. bovis and BCG
Lire plus01 juin 1993
publication
Isolation of a proline-rich mycobacterial protein eliciting delayed-type hypersensitivity reactions only in guinea pigs immunized with living mycobacteria
Lire plus01 févr. 1993
publication
Identification of a Mycobacterium bovis BCG 45/47-kilodalton antigen complex, an immunodominant target for antibody response after immunization with living bacteria
Lire plus01 sept. 1985