Ligne de temps

Pascale Pescher
Ingénieur(e) de Recherche
22 Jun 2020
publication

Dynamic imaging reveals surface exposure of virulent Leishmania amastigotes during pyroptosis of infected macrophages.

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20 Feb 2020
publication

SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani.

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14 Feb 2019
project

Private: PTR 403 – Generation and validation of innovative tools for 2D- and 3D-real time imaging of trypanosomatid parasites in their mammalian hosts

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24 Jan 2019
project

H2020-MSA-RISE-2017: LeiSHield-MATI consortium

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16 Jan 2019
project

“Modelling and functional analysis of clonal Evolution in Leishmania – possible role of non-coding RNAs and RNA modification”

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19 Sep 2018
publication

Reverse Epidemiology: An Experimental Framework to Drive Biomarker Discovery by Functional Genetic Screening Using Relevant Animal Models

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12 Apr 2018
publication

Stage-specific expression of the proline-alanine transporter in the human pathogen Leishmania

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06 Nov 2017
publication

Haplotype selection as an adaptive mechanism in the protozoan pathogen Leishmania donovani

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25 Sep 2017
publication

New insights into experimental visceral leishmaniasis: Real-time in vivo imaging of Leishmania donovani virulence

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23 May 2017
publication

Modulation of Aneuploidy in during Adaptation to Different and Environments and Its Impact on Gene Expression

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16 Jun 2016
publication

Phenotypic Characterization of a Leishmania donovani Cyclophilin 40 Null Mutant

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14 Sep 2015
project

PTR 392 – Systems-wide analysis of Leishmania virulence

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07 Sep 2015
project

LeiSHield – A new collaborative action to determine prevalence, anticipate emergence and assess urbanization of cutaneous and visceral leishmaniasis in LeishRIIP partner countries

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11 May 2015
team

Parasitologie moléculaire et Signalisation

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23 Dec 2013
publication

Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection

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21 Jul 2011
publication

Alba-domain proteins of Trypanosoma brucei are cytoplasmic RNA-binding proteins that interact with the translation machinery

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26 Apr 2011
publication

Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation

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21 Apr 2011
publication

Imaging host cell-Leishmania interaction dynamics implicates parasite motility, lysosome recruitment, and host cell wounding in the infection process

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01 Nov 2010
publication

Identification of Leishmania-specific protein phosphorylation sites by LC-ESI-MS/MS and comparative genomics analyses

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23 Jul 2009
publication

A dynamic map of antigen recognition by CD4 T cells at the site of Leishmania major infection

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01 Jun 2005
publication

In vivo efficiency of targeted norfloxacin against persistent, isoniazid-insensitive, Mycobacterium bovis BCG present in the physiologically hypoxic mouse liver

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03 Jan 2005
publication

Targeted norfloxacin is active in vivo against persistent Mycobacterium bovis BCG

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01 Oct 2003
publication

Enhanced cloning efficiency of mouse bone marrow macrophage progenitors correlates with increased content of CSF-1 receptor of their progeny at low oxygen tension

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01 Jan 2003
publication

Characterization of a putative type IV aminophospholipid transporter P-type ATPase

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01 Nov 2002
publication

[Preliminary study on isoniazid-epiroprim combination in a tuberculosis murine model]

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06 Apr 2001
publication

Mixed immune response induced in rodents by two naked DNA genes coding for mycobacterial glycosylated proteins

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01 Jan 2001
publication

Role of Mycobacterium tuberculosis copper-zinc superoxide dismutase

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01 Nov 1999
publication

Deglycosylation of the 45/47-kilodalton antigen complex of Mycobacterium tuberculosis decreases its capacity to elicit in vivo or in vitro cellular immune responses

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16 Oct 1996
publication

Characterization of murine monoclonal antibodies specific for the 45/47 kDa antigen complex (APA) of Mycobacterium tuberculosis, M. bovis and BCG

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01 Jun 1993
publication

Isolation of a proline-rich mycobacterial protein eliciting delayed-type hypersensitivity reactions only in guinea pigs immunized with living mycobacteria

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01 Feb 1993
publication

Identification of a Mycobacterium bovis BCG 45/47-kilodalton antigen complex, an immunodominant target for antibody response after immunization with living bacteria

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01 Sep 1985
publication

Preparation of tuberculin antigen L

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