Timeline

Marie Desnos-Ollivier

Deputy Director of National Reference Center

29 Mar 2024

publication

Features of cryptococcosis among 652 HIV-seronegative individuals in France: a cross-sectional observational study (2005-2020).

13 Jun 2023

publication

Coregulation of extracellular vesicle production and fluconazole susceptibility in Cryptococcus neoformans

02 Jan 2023

team

Translational Mycology

01 Nov 2022

publication

Increasing number of cases and outbreaks caused by Candida auris in the EU/EEA, 2020 to 2021.

12 Sep 2022

publication

First Patient-to-Patient Intrahospital Transmission of Clade I Candida auris in France Revealed after a Two-Month Incubation Period.

28 Jun 2022

publication

Active Surveillance Program to Increase Awareness on Invasive Fungal Diseases: the French RESSIF Network (2012 to 2018).

14 Jun 2022

news

Important publication by the French National Reference Center for Invasive Mycoses & Antifungals summarizing 7 years of nationwide surveillance of these severe infections

17 May 2022

publication

Echinocandins Susceptibility Patterns of 2,787 Yeast Isolates: Importance of the Thresholds for the Detection of FKS Mutations.

26 Oct 2021

publication

Cryptococcus gattii Species Complex as an Opportunistic Pathogen: Underlying Medical Conditions Associated with the Infection.

14 Sep 2021

course

MOOC Medical Mycology

01 Sep 2021

publication

Earliest case of Candida auris infection imported in 2007 in Europe from India prior to the 2009 description in Japan.

01 Jun 2021

publication

Kazachstania slooffiae: An unexpected journey to a human pleural sample.

18 May 2021

publication

Azole Susceptibility Profiles of More than 9,000 Clinical Yeast Isolates Belonging to 40 Common and Rare Species.

16 Mar 2021

publication

Cryptococcus gattii in Patients with Lymphoid Neoplasms: An Illustration of Evolutive Host-Fungus Interactions.

04 Mar 2021

publication

Central nervous system candidiasis beyond neonates: Lessons from a nationwide study.

18 Feb 2021

publication

A Short-Tandem-Repeat Assay (MmySTR) for Studying Genetic Variation in Madurella mycetomatis.

01 Jan 2021

publication

No Impact of Fluconazole to Echinocandins Replacement as First-Line Therapy on the Epidemiology of Yeast Fungemia (Hospital-Driven Active Surveillance, 2004-2017, Paris, France).

14 Dec 2020

publication

Case Report: Emergence of Candida auris in the Indian Ocean Region.

01 Sep 2020

publication

Saprochaete clavata Outbreak Infecting Cancer Center through Dishwasher.

01 Sep 2020

publication

Epidemiological investigation for grouped cases of Trichosporon asahii using whole genome and IGS1 sequencing.

01 Aug 2020

publication

Diagnostic implications of mycetoma derived from Madurella pseudomycetomatis isolates from Mexico.

01 Jul 2020

publication

The genus Madurella: Molecular identification and epidemiology in Sudan.

01 Jul 2020

publication

Yarrowia lipolytica causes sporadic cases and local outbreaks of infections and colonisation.

28 Apr 2020

publication

Tracing the Evolutionary History and Global Expansion of Candida auris Using Population Genomic Analyses.

01 Jan 2020

publication

Comparison of MultiLocus Sequence Typing (MLST) and Microsatellite Length Polymorphism (MLP) for Pneumocystis jirovecii genotyping.

01 Jan 2020

publication

Madurella real-time PCR, a novel approach for eumycetoma diagnosis.

01 Aug 2019

publication

Genotypes and population genetics of cryptococcus neoformans and cryptococcus gattii species complexes in Europe and the mediterranean area.

01 May 2019

publication

Isavuconazole MIC distribution of 29 yeast species responsible for invasive infections (2015-2017).

01 Mar 2019

publication

Database establishment for the secondary fungal DNA barcode translational elongation factor 1α (TEF1α) 1.

28 Jan 2019

project

Genomic studies of grouped cases involving rare yeast species

01 Jan 2019

publication

Dual DNA Barcoding for the Molecular Identification of the Agents of Invasive Fungal Infections.

01 Apr 2018

publication

Population Structure of Candida parapsilosis: No Genetic Difference Between French and Uruguayan Isolates Using Microsatellite Length Polymorphism.

01 Oct 2017

publication

Fundamental niche prediction of the pathogenic yeasts Cryptococcus neoformans and Cryptococcus gattii in Europe.

01 Aug 2017

publication

Diversity of Pneumocystis jirovecii Across Europe: A Multicentre Observational Study.

21 Jul 2017

publication

Rearranged Biosynthetic Gene Cluster and Synthesis of Hassallidin E in Planktothrix serta PCC 8927

01 Jul 2017

publication

Investigating Clinical Issues by Genotyping of Medically Important Fungi: Why and How?

01 Jun 2017

publication

Predisposing factors and outcome of uncommon yeast species-related fungaemia based on an exhaustive surveillance programme (2002-14).

01 May 2017

publication

The risk and clinical outcome of candidemia depending on underlying malignancy.

01 Dec 2016

publication

Recurrent episodes of Candidemia due to Candida glabrata, Candida tropicalis and Candida albicans with acquired echinocandin resistance.

01 Nov 2016

publication

Environmental distribution of Cryptococcus neoformans and C. gattii around the Mediterranean basin.

01 Jul 2016

publication

Novel Taxa Associated with Human Fungal Black-Grain Mycetomas: Emarellia grisea gen. nov., sp. nov., and Emarellia paragrisea sp. nov.

01 Jun 2016

publication

Environmental distribution of Cryptococcus neoformans and C. gattii around the Mediterranean basin.

01 Feb 2016

publication

Multilocus sequence typing analysis reveals that Cryptococcus neoformans var. neoformans is a recombinant population.

01 Jan 2016

publication

Fluconazole and Echinocandin Resistance of Candida glabrata Correlates Better with Antifungal Drug Exposure Rather than with MSH2 Mutator Genotype in a French Cohort of Patients Harboring Low Rates of Resistance.

01 Jan 2016

publication

Typing Candida Species Using Microsatellite Length Polymorphism and Multilocus Sequence Typing.

01 Oct 2015

publication

Application of Isothermal Amplification Techniques for Identification of Madurella mycetomatis, the Prevalent Agent of Human Mycetoma.

14 Jul 2015

tool

Databases on the epidemiology of invasive fungal infections in France

14 Jul 2015

tool

Institut Pasteur FungiBank

14 Jul 2015

nrc

Invasive Mycoses and Antifungals

13 Jun 2015

project

Phylogenetic studies on fungi causing invasive infections

09 Jun 2015

publication

Cryptococcosis Serotypes Impact Outcome and Provide Evidence of Cryptococcus neoformans Speciation.

11 May 2015

department

Mycology

01 May 2015

publication

International Society of Human and Animal Mycology (ISHAM)-ITS reference DNA barcoding database–the quality controlled standard tool for routine identification of human and animal pathogenic fungi.

01 Jan 2015

publication

Development of echinocandin resistance in Candida krusei isolates following exposure to micafungin and caspofungin in a BM transplant unit.

16 Dec 2014

publication

Multicenter outbreak of infections by Saprochaete clavata, an unrecognized opportunistic fungal pathogen.

06 Aug 2014

publication

Worrisome trends in incidence and mortality of candidemia in intensive care units (Paris area, 2002-2010).

01 Jun 2014

publication

Misidentification of Saprochaete clavata as Magnusiomyces capitatus in clinical isolates: utility of internal transcribed spacer sequencing and matrix-assisted laser desorption ionization-time of flight mass spectrometry and importance of reliable databases.

01 Apr 2012

publication

Diagnosis, management and outcome of Candida endocarditis.

01 Jan 2012

publication

Antifungal susceptibility profiles of 1698 yeast reference strains revealing potential emerging human pathogens.

01 Jan 2012

publication

Genetic Diversity and Genomic Plasticity of Cryptococcus neoformans AD Hybrid Strains.

01 Jan 2012

publication

Candida spp. with acquired echinocandin resistance, France, 2004-2010.

01 Nov 2011

publication

Prior caspofungin exposure in patients with hematological malignancies is a risk factor for subsequent fungemia due to decreased susceptibility in Candida spp.: a case-control study in Paris, France.

01 Jun 2011

publication

Development of echinocandin resistance in Clavispora lusitaniae during caspofungin treatment.

01 Feb 2011

publication

Black grain mycetoma caused by Leptosphaeria tompkinsii.

01 Jan 2011

publication

Dynamics of Cryptococcus neoformans-macrophage interactions reveal that fungal background influences outcome during cryptococcal meningoencephalitis in humans.

15 Nov 2010

publication

Recent exposure to caspofungin or fluconazole influences the epidemiology of candidemia: a prospective multicenter study involving 2,441 patients.

18 May 2010

publication

Mixed infections and In Vivo evolution in the human fungal pathogen Cryptococcus neoformans.

15 Jan 2009

publication

Evidence that graft-site candidiasis after kidney transplantation is acquired during organ recovery: a multicenter study in France.

01 Oct 2008

publication

Debaryomyces hansenii (Candida famata), a rare human fungal pathogen often misidentified as Pichia guilliermondii (Candida guilliermondii).

01 Sep 2008

publication

Fatal-stroke syndrome revealing fungal cerebral vasculitis due to Arthrographis kalrae in an immunocompetent patient.

01 Sep 2008

publication

Mutations in the fks1 gene in Candida albicans, C. tropicalis, and C. krusei correlate with elevated caspofungin MICs uncovered in AM3 medium using the method of the European Committee on Antibiotic Susceptibility Testing.

01 Jul 2008

publication

Detection of caspofungin resistance in Candida spp. by Etest.

01 Apr 2008

publication

Clonal population of flucytosine-resistant Candida tropicalis from blood cultures, Paris, France.

01 Dec 2007

publication

Comparison of microsatellite length polymorphism and multilocus sequence typing for DNA-Based typing of Candida albicans.

01 Oct 2007

publication

Peritonitis due to Blastobotrys proliferans in a patient undergoing continuous ambulatory peritoneal dialysis.

01 Jun 2007

publication

Acquired resistance to echinocandins in Candida albicans: case report and review.

01 Oct 2006

publication

A little guide for advanced search:

Features of cryptococcosis among 652 HIV-seronegative individuals in France: a cross-sectional observational study (2005-2020).

Coregulation of extracellular vesicle production and fluconazole susceptibility in Cryptococcus neoformans

Translational Mycology

Increasing number of cases and outbreaks caused by Candida auris in the EU/EEA, 2020 to 2021.

First Patient-to-Patient Intrahospital Transmission of Clade I Candida auris in France Revealed after a Two-Month Incubation Period.

Active Surveillance Program to Increase Awareness on Invasive Fungal Diseases: the French RESSIF Network (2012 to 2018).

Important publication by the French National Reference Center for Invasive Mycoses & Antifungals summarizing 7 years of nationwide surveillance of these severe infections

Echinocandins Susceptibility Patterns of 2,787 Yeast Isolates: Importance of the Thresholds for the Detection of FKS Mutations.

Cryptococcus gattii Species Complex as an Opportunistic Pathogen: Underlying Medical Conditions Associated with the Infection.

MOOC Medical Mycology

Earliest case of Candida auris infection imported in 2007 in Europe from India prior to the 2009 description in Japan.

Kazachstania slooffiae: An unexpected journey to a human pleural sample.

Azole Susceptibility Profiles of More than 9,000 Clinical Yeast Isolates Belonging to 40 Common and Rare Species.

Cryptococcus gattii in Patients with Lymphoid Neoplasms: An Illustration of Evolutive Host-Fungus Interactions.

Central nervous system candidiasis beyond neonates: Lessons from a nationwide study.

A Short-Tandem-Repeat Assay (MmySTR) for Studying Genetic Variation in Madurella mycetomatis.

No Impact of Fluconazole to Echinocandins Replacement as First-Line Therapy on the Epidemiology of Yeast Fungemia (Hospital-Driven Active Surveillance, 2004-2017, Paris, France).

Case Report: Emergence of Candida auris in the Indian Ocean Region.

Saprochaete clavata Outbreak Infecting Cancer Center through Dishwasher.

Epidemiological investigation for grouped cases of Trichosporon asahii using whole genome and IGS1 sequencing.

Diagnostic implications of mycetoma derived from Madurella pseudomycetomatis isolates from Mexico.

The genus Madurella: Molecular identification and epidemiology in Sudan.

Yarrowia lipolytica causes sporadic cases and local outbreaks of infections and colonisation.

Tracing the Evolutionary History and Global Expansion of Candida auris Using Population Genomic Analyses.

Comparison of MultiLocus Sequence Typing (MLST) and Microsatellite Length Polymorphism (MLP) for Pneumocystis jirovecii genotyping.

Madurella real-time PCR, a novel approach for eumycetoma diagnosis.

Genotypes and population genetics of cryptococcus neoformans and cryptococcus gattii species complexes in Europe and the mediterranean area.

Isavuconazole MIC distribution of 29 yeast species responsible for invasive infections (2015-2017).

Database establishment for the secondary fungal DNA barcode translational elongation factor 1α (TEF1α) 1.

Genomic studies of grouped cases involving rare yeast species

Dual DNA Barcoding for the Molecular Identification of the Agents of Invasive Fungal Infections.

Population Structure of Candida parapsilosis: No Genetic Difference Between French and Uruguayan Isolates Using Microsatellite Length Polymorphism.

Fundamental niche prediction of the pathogenic yeasts Cryptococcus neoformans and Cryptococcus gattii in Europe.

Diversity of Pneumocystis jirovecii Across Europe: A Multicentre Observational Study.

Rearranged Biosynthetic Gene Cluster and Synthesis of Hassallidin E in Planktothrix serta PCC 8927

Investigating Clinical Issues by Genotyping of Medically Important Fungi: Why and How?

Predisposing factors and outcome of uncommon yeast species-related fungaemia based on an exhaustive surveillance programme (2002-14).

The risk and clinical outcome of candidemia depending on underlying malignancy.

Recurrent episodes of Candidemia due to Candida glabrata, Candida tropicalis and Candida albicans with acquired echinocandin resistance.

Environmental distribution of Cryptococcus neoformans and C. gattii around the Mediterranean basin.

Novel Taxa Associated with Human Fungal Black-Grain Mycetomas: Emarellia grisea gen. nov., sp. nov., and Emarellia paragrisea sp. nov.

Environmental distribution of Cryptococcus neoformans and C. gattii around the Mediterranean basin.

Multilocus sequence typing analysis reveals that Cryptococcus neoformans var. neoformans is a recombinant population.

Fluconazole and Echinocandin Resistance of Candida glabrata Correlates Better with Antifungal Drug Exposure Rather than with MSH2 Mutator Genotype in a French Cohort of Patients Harboring Low Rates of Resistance.

Typing Candida Species Using Microsatellite Length Polymorphism and Multilocus Sequence Typing.

Application of Isothermal Amplification Techniques for Identification of Madurella mycetomatis, the Prevalent Agent of Human Mycetoma.

Databases on the epidemiology of invasive fungal infections in France

Institut Pasteur FungiBank

Invasive Mycoses and Antifungals

Phylogenetic studies on fungi causing invasive infections

Cryptococcosis Serotypes Impact Outcome and Provide Evidence of Cryptococcus neoformans Speciation.

Mycology

International Society of Human and Animal Mycology (ISHAM)-ITS reference DNA barcoding database–the quality controlled standard tool for routine identification of human and animal pathogenic fungi.

Development of echinocandin resistance in Candida krusei isolates following exposure to micafungin and caspofungin in a BM transplant unit.

Multicenter outbreak of infections by Saprochaete clavata, an unrecognized opportunistic fungal pathogen.

Worrisome trends in incidence and mortality of candidemia in intensive care units (Paris area, 2002-2010).

Misidentification of Saprochaete clavata as Magnusiomyces capitatus in clinical isolates: utility of internal transcribed spacer sequencing and matrix-assisted laser desorption ionization-time of flight mass spectrometry and importance of reliable databases.

Diagnosis, management and outcome of Candida endocarditis.

Antifungal susceptibility profiles of 1698 yeast reference strains revealing potential emerging human pathogens.

Genetic Diversity and Genomic Plasticity of Cryptococcus neoformans AD Hybrid Strains.

Candida spp. with acquired echinocandin resistance, France, 2004-2010.

Prior caspofungin exposure in patients with hematological malignancies is a risk factor for subsequent fungemia due to decreased susceptibility in Candida spp.: a case-control study in Paris, France.

Development of echinocandin resistance in Clavispora lusitaniae during caspofungin treatment.

Black grain mycetoma caused by Leptosphaeria tompkinsii.

Dynamics of Cryptococcus neoformans-macrophage interactions reveal that fungal background influences outcome during cryptococcal meningoencephalitis in humans.

Recent exposure to caspofungin or fluconazole influences the epidemiology of candidemia: a prospective multicenter study involving 2,441 patients.

Mixed infections and In Vivo evolution in the human fungal pathogen Cryptococcus neoformans.

Evidence that graft-site candidiasis after kidney transplantation is acquired during organ recovery: a multicenter study in France.

Debaryomyces hansenii (Candida famata), a rare human fungal pathogen often misidentified as Pichia guilliermondii (Candida guilliermondii).

Fatal-stroke syndrome revealing fungal cerebral vasculitis due to Arthrographis kalrae in an immunocompetent patient.

Mutations in the fks1 gene in Candida albicans, C. tropicalis, and C. krusei correlate with elevated caspofungin MICs uncovered in AM3 medium using the method of the European Committee on Antibiotic Susceptibility Testing.

Detection of caspofungin resistance in Candida spp. by Etest.

Clonal population of flucytosine-resistant Candida tropicalis from blood cultures, Paris, France.

Comparison of microsatellite length polymorphism and multilocus sequence typing for DNA-Based typing of Candida albicans.

Peritonitis due to Blastobotrys proliferans in a patient undergoing continuous ambulatory peritoneal dialysis.

Acquired resistance to echinocandins in Candida albicans: case report and review.

Molecular identification of black-grain mycetoma agents.