Timeline

Christophe Rusniok

Research Engineer

22 Dec 2023

project

From the source to the user end: deciphering the impact of microbiome and water parameters on opportunistic waterborne pathogens (MicroPathWater)

12 Sep 2023

news

How the respiratory tract microbiome influences the severity of bacterial pneumonia

17 Aug 2023

publication

The respiratory tract microbiome, the pathogen load, and clinical interventions define severity of bacterial pneumonia.

30 May 2023

news

Legionellosis: the bacteria use a novel strategy to infect more efficiently

14 Apr 2023

publication

Legionella para-effectors target chromatin and promote bacterial replication.

22 Jul 2022

project

Deciphering the virulence of Legionella pneumophila in vivo in the zebrafish model

15 Jul 2022

publication

Genomic erosion and horizontal gene transfer shape functional differences of the ExlA toxin in Pseudomonas spp.

18 Feb 2022

news

Legionellosis: a novel mechanism by which the bacterium Legionella pneumophila regulates the immune response of its host cells

09 Feb 2022

publication

Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune response.

13 Jan 2022

news

The bacterium causing legionellosis modifies the electrochemical potential of host mitochondria to better replicate

09 Dec 2021

publication

Reverting the mode of action of the mitochondrial F O F 1-ATPase by Legionella pneumophila preserves its replication niche

20 May 2020

publication

Persistent Legionnaires’ Disease and Associated Antibiotic Treatment Engender a Highly Disturbed Pulmonary Microbiome Enriched in Opportunistic Microorganisms

05 Feb 2019

publication

More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells.

31 Jan 2019

news

How human pathogens may emerge from the environment

26 Jun 2017

publication

Dynamics and impact of homologous recombination on the evolution of Legionella pneumophila

01 Feb 2017

publication

The Legionella pneumophila genome evolved to accommodate multiple regulatory mechanisms controlled by the CsrA-system.

01 Nov 2016

publication

Multiple major disease-associated clones of Legionella pneumophila have emerged recently and independently.

18 Sep 2015

project

A personal database system for large scale quantitative results exploration (Cassandre, PTR 463)

11 May 2015

team

Biology Of Intracellular Bacteria

18 Oct 2013

publication

[Host epigenetic targeting by Legionella pneumophila]

17 Apr 2013

news

Légionellose : reprogrammation inédite des cellules hôtes à l’avantage de la bactérie Legionella pneumophila

17 Apr 2013

publication

Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication

15 Apr 2013

publication

Reductive evolution in Streptococcus agalactiae and the emergence of a host adapted lineage

24 Apr 2012

publication

Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes

01 Apr 2012

publication

Deep sequencing defines the transcriptional map of L. pneumophila and identifies growth phase-dependent regulated ncRNAs implicated in virulence

01 Dec 2011

publication

Complete genome sequence of the animal pathogen Listeria ivanovii, which provides insights into host specificities and evolution of the genus Listeria

30 Dec 2010

publication

Specific real-time PCR for simultaneous detection and identification of Legionella pneumophila serogroup 1 in water and clinical samples.

15 Dec 2010

publication

Double-stranded RNA adenosine deaminase ADAR-1-induced hypermutated genomes among inactivated seasonal influenza and live attenuated measles virus vaccines

05 Feb 2010

publication

Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis

09 Oct 2009

publication

NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis

01 Sep 2009

publication

Legionella pneumophila: population genetics, phylogeny and genomics.

19 Aug 2009

publication

Legionella pneumophila – Host Interactions: Insights Gained from Comparative Genomics and Cell Biology.

01 Apr 2009

publication

Genome sequence of Vibrio splendidus: an abundant planctonic marine species with a large genotypic diversity

26 Jan 2009

publication

Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G

18 Dec 2008

publication

Atypical association of DDE transposition with conjugation specifies a new family of mobile elements

02 Oct 2008

publication

Shaping a bacterial genome by large chromosomal replacements, the evolutionary history of Streptococcus agalactiae

16 Oct 2006

publication

Specific regions of genome plasticity and genetic diversity of the commensal Escherichia coli A0 34/86

08 Sep 2006

publication

Twin gradients in APOBEC3 edited HIV-1 DNA reflect the dynamics of lentiviral replication

19 Jan 2006

publication

Genomic diversity and evolution within the species Streptococcus agalactiae

01 Jan 2006

publication

A SAGE approach to identifying novel trans-acting factors involved in the X inactivation process

01 Jun 2005

publication

The SrtA Sortase of Streptococcus agalactiae is required for cell wall anchoring of proteins containing the LPXTG motif, for adhesion to epithelial cells, and for colonization of the mouse intestine

01 Feb 2005

publication

Characterization of the flexible genome complement of the commensal Escherichia coli strain A0 34/86 (O83 : K24 : H31).

03 Oct 2004

publication

Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity

29 Jan 2004

publication

CAAT-Box, Contigs-Assembly and Annotation Tool-Box for genome sequencing projects

05 Oct 2003

publication

The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens

01 Jun 2003

publication

Multilocus sequence typing system for group B streptococcus

01 Apr 2003

publication

Comparison of the genome sequences of Listeria monocytogenes and Listeria innocua: clues for evolution and pathogenicity

01 Sep 2002

publication

Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease

19 Dec 2000

publication

Gene expression profiles in normal and Otx2-/- early gastrulating mouse embryos

01 Nov 2000

publication

The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneri

01 Sep 1999

publication

The 102-kilobase pgm locus of Yersinia pestis: sequence analysis and comparison of selected regions among different Yersinia pestis and Yersinia pseudotuberculosis strains

A little guide for advanced search:

From the source to the user end: deciphering the impact of microbiome and water parameters on opportunistic waterborne pathogens (MicroPathWater)

How the respiratory tract microbiome influences the severity of bacterial pneumonia

The respiratory tract microbiome, the pathogen load, and clinical interventions define severity of bacterial pneumonia.

Legionellosis: the bacteria use a novel strategy to infect more efficiently

Legionella para-effectors target chromatin and promote bacterial replication.

Deciphering the virulence of Legionella pneumophila in vivo in the zebrafish model

Genomic erosion and horizontal gene transfer shape functional differences of the ExlA toxin in Pseudomonas spp.

Legionellosis: a novel mechanism by which the bacterium Legionella pneumophila regulates the immune response of its host cells

Translocated Legionella pneumophila small RNAs mimic eukaryotic microRNAs targeting the host immune response.

The bacterium causing legionellosis modifies the electrochemical potential of host mitochondria to better replicate

Reverting the mode of action of the mitochondrial F O F 1-ATPase by Legionella pneumophila preserves its replication niche

Persistent Legionnaires’ Disease and Associated Antibiotic Treatment Engender a Highly Disturbed Pulmonary Microbiome Enriched in Opportunistic Microorganisms

More than 18,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells.

How human pathogens may emerge from the environment

Dynamics and impact of homologous recombination on the evolution of Legionella pneumophila

The Legionella pneumophila genome evolved to accommodate multiple regulatory mechanisms controlled by the CsrA-system.

Multiple major disease-associated clones of Legionella pneumophila have emerged recently and independently.

A personal database system for large scale quantitative results exploration (Cassandre, PTR 463)

Biology Of Intracellular Bacteria

[Host epigenetic targeting by Legionella pneumophila]

Légionellose : reprogrammation inédite des cellules hôtes à l’avantage de la bactérie Legionella pneumophila

Legionella pneumophila effector RomA uniquely modifies host chromatin to repress gene expression and promote intracellular bacterial replication

Reductive evolution in Streptococcus agalactiae and the emergence of a host adapted lineage

Comparative genomics and transcriptomics of lineages I, II, and III strains of Listeria monocytogenes

Deep sequencing defines the transcriptional map of L. pneumophila and identifies growth phase-dependent regulated ncRNAs implicated in virulence

Complete genome sequence of the animal pathogen Listeria ivanovii, which provides insights into host specificities and evolution of the genus Listeria

Specific real-time PCR for simultaneous detection and identification of Legionella pneumophila serogroup 1 in water and clinical samples.

Double-stranded RNA adenosine deaminase ADAR-1-induced hypermutated genomes among inactivated seasonal influenza and live attenuated measles virus vaccines

Genome sequence of Streptococcus gallolyticus: insights into its adaptation to the bovine rumen and its ability to cause endocarditis

NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitidis

Legionella pneumophila: population genetics, phylogeny and genomics.

Legionella pneumophila – Host Interactions: Insights Gained from Comparative Genomics and Cell Biology.

Genome sequence of Vibrio splendidus: an abundant planctonic marine species with a large genotypic diversity

Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G

Atypical association of DDE transposition with conjugation specifies a new family of mobile elements

Shaping a bacterial genome by large chromosomal replacements, the evolutionary history of Streptococcus agalactiae

Specific regions of genome plasticity and genetic diversity of the commensal Escherichia coli A0 34/86

Twin gradients in APOBEC3 edited HIV-1 DNA reflect the dynamics of lentiviral replication

Genomic diversity and evolution within the species Streptococcus agalactiae

A SAGE approach to identifying novel trans-acting factors involved in the X inactivation process

The SrtA Sortase of Streptococcus agalactiae is required for cell wall anchoring of proteins containing the LPXTG motif, for adhesion to epithelial cells, and for colonization of the mouse intestine

Characterization of the flexible genome complement of the commensal Escherichia coli strain A0 34/86 (O83 : K24 : H31).

Evidence in the Legionella pneumophila genome for exploitation of host cell functions and high genome plasticity

CAAT-Box, Contigs-Assembly and Annotation Tool-Box for genome sequencing projects

The genome sequence of the entomopathogenic bacterium Photorhabdus luminescens

Multilocus sequence typing system for group B streptococcus

Comparison of the genome sequences of Listeria monocytogenes and Listeria innocua: clues for evolution and pathogenicity

Genome sequence of Streptococcus agalactiae, a pathogen causing invasive neonatal disease

Gene expression profiles in normal and Otx2-/- early gastrulating mouse embryos

The virulence plasmid pWR100 and the repertoire of proteins secreted by the type III secretion apparatus of Shigella flexneri

The 102-kilobase pgm locus of Yersinia pestis: sequence analysis and comparison of selected regions among different Yersinia pestis and Yersinia pseudotuberculosis strains