Ligne de temps
Emmanuel Lemichez
Responsable de Structure
22 mars 2024
publication
Caveolin-1 protects endothelial cells from extensive expansion of transcellular tunnel by stiffening the plasma membrane.
Lire plus01 déc. 2023
publication
Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human colonocytes.
Lire plus09 nov. 2023
13 oct. 2022
publication
Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division.
Lire plus05 oct. 2022
publication
The cnf1 gene is associated with an expanding Escherichia coli ST131 H30Rx/C2 subclade and confers a competitive advantage for gut colonization.
Lire plus17 sept. 2022
publication
In Silico Conformational Features of Botulinum Toxins A1 and E1 According to Intraluminal Acidification.
Lire plus15 juil. 2022
publication
C910 chemical compound inhibits the traffiking of several bacterial AB toxins with cross-protection against influenza virus.
Lire plus20 janv. 2022
08 déc. 2021
20 sept. 2021
publication
Conformational Insights into the Control of CNF1 Toxin Activity by Peptidyl-Prolyl Isomerization: A Molecular Dynamics Perspective.
Lire plus01 mai 2021
publication
Characterization of a highly neutralizing single monoclonal antibody to botulinum neurotoxin type A.
Lire plus13 sept. 2019
project
Chronic carriage of CNF1-producing bacteria in the gut and development of colorectal cancer
Lire plus13 sept. 2019
project
Landscape of protein ubiquitylation during infection by CNF1-producing uropathogenic E. coli
Lire plus23 juil. 2019
23 juil. 2019
23 juil. 2019
20 avr. 2019
20 sept. 2018
publication
Ezrin enrichment on curved membranes requires a specific conformation or interaction with a curvature-sensitive partner
Lire plus13 sept. 2018
14 févr. 2018
01 févr. 2018
23 janv. 2018
publication
Group-I PAKs-mediated phosphorylation of HACE1 at serine 385 regulates its oligomerization state and Rac1 ubiquitination
Lire plus23 janv. 2018
publication
Screening of a Drug Library Identifies Inhibitors of Cell Intoxication by CNF1.
Lire plus18 janv. 2018
publication
“Bacterial Toxins” Section in the Journal Toxins: A Fantastic Multidisciplinary Interplay between Bacterial Pathogenicity Mechanisms, Physiological Processes, Genomic Evolution, and Subsequent Development of Identification Methods, Efficient Treatment, and Prevention of Toxigenic Bacteria
Lire plus09 août 2017
06 juil. 2017
23 juin 2017
publication
Ezrin enhances line tension along transcellular tunnel edges via NMIIa driven actomyosin cable formation
Lire plus02 juin 2017
publication
Hsp70 facilitates trans-membrane transport of bacterial ADP-ribosylating toxins into the cytosol of mammalian cells
Lire plus18 mai 2017
publication
Pseudomonas aeruginosa Exolysin promotes bacterial growth in lungs, alveolar damage and bacterial dissemination
Lire plus24 avr. 2017
publication
Staphylococcus aureus Promotes Smed-PGRP-2/Smed-setd8-1 Methyltransferase Signalling in Planarian Neoblasts to Sensitize Anti-bacterial Gene Responses During Re-infection
Lire plus20 mars 2017
publication
Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation
Lire plus16 mars 2017
publication
Decrease of Staphylococcus aureus Virulence by Helcococcus kunzii in a Caenorhabditis elegans Model
Lire plus11 mars 2017
publication
Botulinum neurotoxin type B uses a distinct entry pathway mediated by CDC42 into intestinal cells versus neuronal cells
Lire plus18 janv. 2017
publication
Historical Perspectives and Guidelines for Botulinum Neurotoxin Subtype Nomenclature
Lire plus01 janv. 2017
25 août 2016
publication
Development of Germline-Humanized Antibodies Neutralizing Botulinum Neurotoxin A and B
Lire plus07 août 2016
publication
First isolation of Clostridium indolis in a patient with chronic osteitis: a case report and literature review of human infections related to Clostridium saccharolyticum group species
Lire plus13 juin 2016
publication
Diversity of Group I and II Clostridium botulinum Strains from France Including Recently Identified Subtypes
Lire plus03 juin 2016
publication
Immunoadjuvant Properties of the Rho Activating Factor CNF1 in Prophylactic and Curative Vaccination against Leishmania infantum.
Lire plus21 avr. 2016
publication
A penicillin- and metronidazole-resistant Clostridium botulinum strain responsible for an infant botulism case
Lire plus01 avr. 2016
publication
EGA Protects Mammalian Cells from Clostridium difficile CDT, Clostridium perfringens Iota Toxin and Clostridium botulinum C2 Toxin
Lire plus25 mars 2016
publication
The Tip of the Four N-Terminal α-Helices of Clostridium sordellii Lethal Toxin Contains the Interaction Site with Membrane Phosphatidylserine Facilitating Small GTPases Glucosylation
Lire plus03 mars 2016
publication
System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes
Lire plus03 févr. 2016
publication
A novel Hsp70 inhibitor prevents cell intoxication with the actin ADP-ribosylating Clostridium perfringens iota toxin
Lire plus02 févr. 2016
01 févr. 2016
publication
Translocation and dissemination to target neurons of botulinum neurotoxin type B in the mouse intestinal wall.
Lire plus01 janv. 2016
publication
A cluster of three cases of botulism due to Clostridium baratii type F, France, August 2015
Lire plus01 oct. 2015
publication
Contractile actin cables induced by Bacillus anthracis lethal toxin depend on the histone acetylation machinery.
Lire plus14 août 2015
08 oct. 2012
publication
Role of N-terminal His6-Tags in binding and efficient translocation of polypeptides into cells using anthrax protective antigen (PA)
Lire plus05 août 2011
publication
Cross-reactivity of anthrax and C2 toxin: protective antigen promotes the uptake of botulinum C2I toxin into human endothelial cells
Lire plus25 févr. 2011
publication
Escherichia coli producing CNF1 toxin hijacks Tollip to trigger Rac1-dependent cell invasion
Lire plus20 mai 2010
publication
Transcriptome dysregulation by anthrax lethal toxin plays a key role in induction of human endothelial cell cytotoxicity
Lire plus22 juin 2009
publication
Injection of Staphylococcus aureus EDIN by the Bacillus anthracis protective antigen machinery induces vascular permeability
Lire plus20 mars 2008
05 juin 2006
publication