Ligne de temps
Chiara Zurzolo
Responsable de Structure
09 déc. 2024
08 nov. 2024
09 sept. 2024
publication
Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators
Lire plus02 sept. 2024
publication
The endolysosomal system in conventional and unconventional protein secretion.
Lire plus24 juin 2024
15 mars 2024
publication
Tunneling nanotubes and tumor microtubes-Emerging data on their roles in intercellular communication and pathophysiology: Summary of an International FASEB Catalyst Conference October 2023.
Lire plus01 janv. 2024
01 janv. 2024
01 déc. 2023
publication
CellWalker: a user-friendly and modular computational pipeline for morphological analysis of microscopy images.
Lire plus27 nov. 2023
publication
Tunnelling nanotube formation is driven by Eps8/IRSp53‐dependent linear actin polymerization
Lire plus01 nov. 2023
publication
Identification and Characterization of Tunneling Nanotubes for Intercellular Trafficking.
Lire plus01 juil. 2023
publication
Calcium-binding Cab45 regulates the polarized apical secretion of soluble proteins in epithelial cells.
Lire plus15 juin 2023
news
New publication – Tunnelling nanotubes between neuronal and microglial cells allow bi-directional transfer of α-Synuclein and mitochondria
Lire plus18 mai 2023
publication
Tunnelling nanotubes between neuronal and microglial cells allow bi-directional transfer of α-Synuclein and mitochondria.
Lire plus05 avr. 2023
publication
3D reconstruction of the cerebellar germinal layer reveals tunneling connections between developing granule cells.
Lire plus01 nov. 2022
22 juil. 2022
22 juil. 2022
15 nov. 2021
publication
Seeing eye to eye: photoreceptors employ nanotube-like connections for material transfer
Lire plus17 août 2021
publication
Calcium levels in the Golgi complex regulate clustering and apical sorting of GPI-APs in polarized epithelial cells.
Lire plus01 août 2021
20 juil. 2021
news
Parkinson’s disease: the implication of lysosomes in the propagation of the pathology
Lire plus01 juil. 2021
publication
α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes.
Lire plus04 mai 2021
01 mars 2021
01 févr. 2021
15 janv. 2021
publication
Patient-derived glioblastoma stem cells transfer mitochondria through tunneling nanotubes in tumor organoids.
Lire plus12 nov. 2020
08 oct. 2020
publication
Rab35 and its effectors promote formation of tunneling nanotubes in neuronal cells.
Lire plus01 oct. 2020
01 sept. 2020
30 juin 2020
publication
The best of both worlds- bringing together cell biology and infection at the Institut Pasteur.
Lire plus12 mai 2020
publication
Actin Assembly around the Shigella-Containing Vacuole Promotes Successful Infection.
Lire plus07 janv. 2020
publication
Fine intercellular connections in development: TNTs, cytonemes, or intercellular bridges?
Lire plus02 déc. 2019
publication
The Wnt/Ca2+ pathway is involved in interneuronal communication mediated by tunneling nanotubes.
Lire plus01 déc. 2019
publication
Human NPCs can degrade α-syn fibrils and transfer them preferentially in a cell contact-dependent manner possibly through TNT-like structures.
Lire plus01 sept. 2019
publication
Clustering in the Golgi apparatus governs sorting and function of GPI-APs in polarized epithelial cells.
Lire plus26 août 2019
event
BCI Seminar – “Cytoskeletal cross-talk with integrin adhesion complexes in cell morphogenesis”
Lire plus05 avr. 2019
01 mars 2019
publication
The prion-like spreading of α-synuclein: From in vitro to in vivo models of Parkinson’s disease.
Lire plus21 janv. 2019
publication
Correlative cryo-electron microscopy reveals the structure of TNTs in neuronal cells
Lire plus19 nov. 2018
project
Mechanisms of GPI-anchored protein apical sorting and plasma membrane organization in polarized epithelial cells.
Lire plus18 nov. 2018
project
Prion-like proteins spreading in neurodegenerative diseases: role of Tunneling Nanotubes (TNTs)
Lire plus17 nov. 2018
16 nov. 2018
05 oct. 2018
publication
Rab11a-Rab8a cascade regulates the formation of tunneling nanotubes through vesicle recycling
Lire plus24 juil. 2018
publication
Organization of GPI-anchored proteins at the cell surface and its physiopathological relevance
Lire plus02 juil. 2018
21 mars 2018
event
Pasteur-Weizmann Council Seminar hosted by the Department of Cell Biology and infection – “Characterizing the Host-pathogen Crosstalk at Early Stages of Infection”
Lire plus11 déc. 2017
event
“Capture of transport vesicles at the Golgi by golgin coiled-coil proteins” – Sean Munro
Lire plus11 déc. 2017
11 déc. 2017
event
“Spacetime at the cell scale: how do “clocks” and “rulers” crosstalk to control chromosome segregation during mitosis?” – Helder Maiato
Lire plus01 déc. 2017
publication
GPI-anchored proteins are confined in subdiffraction clusters at the apical surface of polarized epithelial cells
Lire plus17 oct. 2017
publication
Tunneling Nanotubes and Gap Junctions-Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions.
Lire plus29 juil. 2017
19 juil. 2017
publication
The spread of prion-like proteins by lysosomes and tunneling nanotubes: Implications for neurodegenerative diseases
Lire plus19 juil. 2017
publication
α-Synuclein transfer between neurons and astrocytes indicates that astrocytes play a role in degradation rather than in spreading.
Lire plus16 juin 2017
publication
Regulation of sub-compartmental targeting and folding properties of the Prion-like protein Shadoo
Lire plus05 avr. 2017
event
« From fitness comparison to spatial constrains, the many roads of cell competition »
Lire plus22 mars 2017
event
“Molecular and biological drivers of pathological alpha-synuclein propagation and spread” – Kelvin Luk
Lire plus01 mars 2017
publication
Transfer of disrupted-in-schizophrenia 1 aggregates between neuronal-like cells occurs in tunnelling nanotubes and is promoted by dopamine
Lire plus19 janv. 2017
18 janv. 2017
23 déc. 2016
publication
Differential identity of Filopodia and Tunneling Nanotubes revealed by the opposite functions of actin regulatory complexes
Lire plus12 déc. 2016
22 nov. 2016
event
Cell Biology and Infection Day – December 1, 2016 Institut Pasteur, Paris, France Amphithéâtre Duclaux
Lire plus02 sept. 2016
publication
Tunneling nanotubes: A possible highway in the spreading of tau and other prion-like proteins in neurodegenerative diseases
Lire plus22 août 2016
publication
Tunneling nanotubes spread fibrillar α-synuclein by intercellular trafficking of lysosomes
Lire plus08 juil. 2016
07 juil. 2016
publication
PrPC Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK Cells
Lire plus03 mai 2016
13 avr. 2016
publication
The 37/67 kDa laminin receptor (LR) inhibitor, NSC47924, affects 37/67 kDa LR cell surface localization and interaction with the cellular prion protein
Lire plus16 mars 2016
publication
Drosophila cells use nanotube-like structures to transfer dsRNA and RNAi machinery between cells.
Lire plus09 févr. 2016
publication
Astrocyte-to-neuron intercellular prion transfer is mediated by cell-cell contact
Lire plus17 déc. 2015
publication
Glycosylphosphatidylinositol-anchored proteins: Membrane organization and transport
Lire plus01 juin 2015
publication
Identification and Characterization of Tunneling Nanotubes for Intercellular Trafficking
Lire plus27 mai 2015
11 mai 2015
15 avr. 2015
publication
Trafficking and Membrane Organization of GPI-Anchored Proteins in Health and Diseases
Lire plus30 mars 2015
01 mars 2015
16 sept. 2014
06 juin 2014
publication
Sorting of GPI-anchored proteins from yeast to mammals–common pathways at different sites?
Lire plus04 juin 2014
30 mars 2014
publication
Golgi sorting regulates organization and activity of GPI proteins at apical membranes
Lire plus10 déc. 2013
publication
Exploring the role of lipids in intercellular conduits: breakthroughs in the pipeline
Lire plus31 oct. 2013
publication
The fate of PrP GPI-anchor signal peptide is modulated by P238S pathogenic mutation
Lire plus25 juil. 2013
19 juil. 2013
18 juin 2013
publication
Transfer of polyglutamine aggregates in neuronal cells occurs in tunneling nanotubes
Lire plus15 mai 2013
publication
The cell biology of prion-like spread of protein aggregates: mechanisms and implication in neurodegeneration
Lire plus15 mars 2013
publication
Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation
Lire plus15 févr. 2013
publication
4-hydroxytamoxifen leads to PrPSc clearance by conveying both PrPC and PrPSc to lysosomes independently of autophagy
Lire plus27 nov. 2012
publication
Small misfolded Tau species are internalized via bulk endocytosis and anterogradely and retrogradely transported in neurons
Lire plus10 avr. 2012
07 mars 2012
publication
Wiring through tunneling nanotubes–from electrical signals to organelle transfer
Lire plus28 févr. 2012
publication
Determining the role of mononuclear phagocytes in prion neuroinvasion from the skin
Lire plus12 oct. 2011
publication
N-Glycosylation instead of cholesterol mediates oligomerization and apical sorting of GPI-APs in FRT cells
Lire plus07 sept. 2011
publication
Cluvenone induces apoptosis via a direct target in mitochondria: a possible mechanism to circumvent chemo-resistance?
Lire plus15 oct. 2010
publication
Characterization of the role of dendritic cells in prion transfer to primary neurons
Lire plus23 déc. 2009
publication
Doppel and PrPC co-immunoprecipitate in detergent-resistant membrane domains of epithelial FRT cells
Lire plus08 juin 2009
publication
Lipid rafts and clathrin cooperate in the internalization of PrP in epithelial FRT cells
Lire plus08 mai 2009
01 avr. 2009
15 mars 2009
08 févr. 2009
15 déc. 2008
publication
Different GPI-attachment signals affect the oligomerisation of GPI-anchored proteins and their apical sorting
Lire plus06 sept. 2008
publication
N- and O-glycans are not directly involved in the oligomerization and apical sorting of GPI proteins
Lire plus12 août 2008
publication
Selective roles for cholesterol and actin in compartmentalization of different proteins in the Golgi and plasma membrane of polarized cells
Lire plus04 juin 2008
publication
alpha-Adducin mutations increase Na/K pump activity in renal cells by affecting constitutive endocytosis: implications for tubular Na reabsorption
Lire plus10 avr. 2008
publication
Coexpression of wild-type and mutant prion proteins alters their cellular localization and partitioning into detergent-resistant membranes
Lire plus25 nov. 2007
publication
Gene expression profile of quinacrine-cured prion-infected mouse neuronal cells
Lire plus15 sept. 2007
publication
Distinct v-SNAREs regulate direct and indirect apical delivery in polarized epithelial cells
Lire plus07 juin 2007
publication
Characterization of the properties and trafficking of an anchorless form of the prion protein
Lire plus01 mars 2007
publication
Oligomerization is a specific requirement for apical sorting of glycosyl-phosphatidylinositol-anchored proteins but not for non-raft-associated apical proteins
Lire plus20 sept. 2006
publication
Analysis of detergent-resistant membranes associated with apical and basolateral GPI-anchored proteins in polarized epithelial cells
Lire plus20 mars 2006
publication
GPI-anchored proteins are directly targeted to the apical surface in fully polarized MDCK cells
Lire plus01 févr. 2006
publication
Detergent-resistant membrane domains but not the proteasome are involved in the misfolding of a PrP mutant retained in the endoplasmic reticulum
Lire plus01 janv. 2006
24 oct. 2005
publication
Plasma membrane and lysosomal localization of CB1 cannabinoid receptor are dependent on lipid rafts and regulated by anandamide in human breast cancer cells
Lire plus01 mai 2005
publication
A y(+)LAT-1 mutant protein interferes with y(+)LAT-2 activity: implications for the molecular pathogenesis of lysinuric protein intolerance
Lire plus01 févr. 2005
01 janv. 2005
publication
Functional interaction between p75NTR and TrkA: the endocytic trafficking of p75NTR is driven by TrkA and regulates TrkA-mediated signalling
Lire plus22 nov. 2004
publication
Protein oligomerization modulates raft partitioning and apical sorting of GPI-anchored proteins
Lire plus01 juil. 2004
publication
The Shp-1 and Shp-2, tyrosine phosphatases, are recruited on cell membrane in two distinct molecular complexes including Ret oncogenes
Lire plus30 juin 2004
publication
PrP(C) association with lipid rafts in the early secretory pathway stabilizes its cellular conformation
Lire plus15 avr. 2004
publication
The neuroendocrine protein VGF is sorted into dense-core granules and is secreted apically by polarized rat thyroid epithelial cells
Lire plus01 avr. 2004
21 nov. 2003
01 févr. 2003
01 nov. 2002
publication
PrPC is sorted to the basolateral membrane of epithelial cells independently of its association with rafts
Lire plus01 avr. 2002
publication
Differential recognition of a tyrosine-dependent signal in the basolateral and endocytic pathways of thyroid epithelial cells
Lire plus01 févr. 2002
publication