Ligne de temps
Simon Wain-Hobson
Responsable de Structure
12 févr. 2016
14 oct. 2014
09 oct. 2014
16 juil. 2014
01 avr. 2014
24 oct. 2013
publication
Pandemic influenza viruses: time to recognize our inability to predict the unpredictable and stop dangerous gain-of-function experiments
Lire plus18 oct. 2013
20 août 2013
publication
Human APOBEC3A isoforms translocate to the nucleus and induce DNA double strand breaks leading to cell stress and death
Lire plus20 juin 2013
publication
Efficient deamination of 5-methylcytidine and 5-substituted cytidine residues in DNA by human APOBEC3A cytidine deaminase
Lire plus28 mars 2013
28 déc. 2012
02 oct. 2012
publication
Universal cancer peptide-based therapeutic vaccine breaks tolerance against telomerase and eradicates established tumor
Lire plus19 sept. 2012
publication
Hyperediting of human T-cell leukemia virus type 2 and simian T-cell leukemia virus type 3 by the dsRNA adenosine deaminase ADAR-1
Lire plus13 sept. 2012
06 juin 2012
publication
Structural variability of the herpes simplex virus 1 genome in vitro and in vivo
Lire plus17 janv. 2012
publication
Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions
Lire plus12 oct. 2011
01 juin 2011
publication
Genetic editing of herpes simplex virus 1 and Epstein-Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in culture and in vivo
Lire plus31 mars 2011
publication
Fitness ranking of individual mutants drives patterns of epistatic interactions in HIV-1
Lire plus02 mars 2011
publication
Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism
Lire plus15 déc. 2010
publication
Double-stranded RNA adenosine deaminase ADAR-1-induced hypermutated genomes among inactivated seasonal influenza and live attenuated measles virus vaccines
Lire plus21 juil. 2010
publication
Immunogenicity of a recombinant lentiviral vector carrying human telomerase tumor antigen in HLA-B*0702 transgenic mice
Lire plus28 mai 2010
publication
APOBEC1 and APOBEC3 cytidine deaminases as restriction factors for hepadnaviral genomes in non-humans in vivo
Lire plus27 mai 2010
12 mai 2010
publication
APOBEC3G generates nonsense mutations in human T-cell leukemia virus type 1 proviral genomes in vivo
Lire plus21 oct. 2009
17 juin 2009
publication
Oral administration of low doses of plant-based HBsAg induced antigen-specific IgAs and IgGs in mice, without increasing levels of regulatory T cells
Lire plus12 mars 2009
26 janv. 2009
publication
Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G
Lire plus01 nov. 2008
publication
Murine APOBEC1 is a powerful mutator of retroviral and cellular RNA in vitro and in vivo
Lire plus02 juil. 2008
publication
Immunogenicity and tolerance following HIV-1/HBV plant-based oral vaccine administration
Lire plus30 mai 2008
publication
Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs
Lire plus11 avr. 2008
publication
Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions
Lire plus14 févr. 2007
publication
Induction of mutations in Drosophila melanogaster gypsy retroelements by modulation of intracellular deoxynucleoside triphosphate pools in vivo
Lire plus08 sept. 2006
publication
Twin gradients in APOBEC3 edited HIV-1 DNA reflect the dynamics of lentiviral replication
Lire plus22 août 2006
publication
Optimisation of secretion of recombinant HBsAg virus-like particles: Impact on the development of HIV-1/HBV bivalent vaccines
Lire plus21 mars 2006
publication
The HIV-1 clade C promoter is particularly well adapted to replication in the gut in primary infection
Lire plus01 mars 2006
publication
Clade-specific differences in active viral replication and compartmentalization
Lire plus01 janv. 2006
01 déc. 2005
publication
The majority of human immunodeficiency virus type 1 particles present within splenic germinal centres are produced locally
Lire plus01 sept. 2005
publication
Extensive editing of a small fraction of human T-cell leukemia virus type 1 genomes by four APOBEC3 cytidine deaminases
Lire plus01 févr. 2005
publication
HIV-1 clade promoters strongly influence spatial and temporal dynamics of viral replication in vivo
Lire plus01 janv. 2005
publication
Recovery of APOBEC3-edited human immunodeficiency virus G->A hypermutants by differential DNA denaturation PCR
Lire plus15 déc. 2004
publication
A universal primer set for PCR amplification of nuclear histone H4 genes from all animal species
Lire plus30 avr. 2004
publication
APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase
Lire plus01 févr. 2004
publication
Simian immunodeficiency virus promoter exchange results in a highly attenuated strain that protects against uncloned challenge virus
Lire plus01 oct. 2003
01 avr. 2003
publication
Network analysis of human and simian immunodeficiency virus sequence sets reveals massive recombination resulting in shorter pathways
Lire plus01 nov. 2002
publication
Identification of a hepatitis B virus genome in wild chimpanzees (Pan troglodytes schweinfurthi) from East Africa indicates a wide geographical dispersion among equatorial African primates
Lire plus28 mai 2002
publication
Analysis of a library of macaque nuclear mitochondrial sequences confirms macaque origin of divergent sequences from old oral polio vaccine samples
Lire plus01 avr. 2002
publication
Sustained G–>A hypermutation during reverse transcription of an entire human immunodeficiency virus type 1 strain Vau group O genome
Lire plus01 mars 2002