Ligne de temps

Jean-Pierre Vartanian
Responsable de Structure
08 janv. 2024
event

Club viro: SARS-CoV2 RBD-Specific Antibodies /// APOBEC3F & Monkeypox virus

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22 déc. 2023
course

Viral Outbreaks and Pandemics, A One Health Approach MOOC

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08 sept. 2023
event

Club viro: Influenza A virus & TDP-43 /// SARS-CoV-2-mediated cell hijacking

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24 mai 2023
publication

APOBEC3F is a mutational driver of the human Monkeypox virus identified in the 2022 outbreak.

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04 janv. 2023
team

Virus et stress cellulaire

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08 nov. 2022
event

« Population dynamics of RNA arthropod-borne viruses in experimental evolution »

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15 sept. 2022
event

“Structural biology of beneficial viruses: the anatomy of a flagellotropic bacteriophage and surprises in the architecture of flaviviruses.”

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12 janv. 2022
publication

APOBEC3C S188I Polymorphism Enhances Context-Specific Editing of Hepatitis B Virus Genome.

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16 déc. 2021
course

Emerging and re-emerging viruses MOOC

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09 sept. 2021
course

MOOC Viruses and Human Cancers

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14 août 2021
publication

Frame-shifted APOBEC3A encodes two alternative proapoptotic proteins that target the mitochondrial network.

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01 avr. 2019
publication

Hypoxia-induced human deoxyribonuclease I is a cellular restriction factor of hepatitis B virus.

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28 févr. 2019
publication

Genotoxic stress increases cytoplasmic mitochondrial DNA editing by human APOBEC3 mutator enzymes at a single cell level.

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24 janv. 2019
publication

Elephant APOBEC3A cytidine deaminase induces massive double-stranded DNA breaks and apoptosis.

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12 juin 2018
publication

The rabbit as an orthologous small animal model for APOBEC3A oncogenesis.

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12 nov. 2014
publication

ADAR1 enhances HTLV-1 and HTLV-2 replication through inhibition of PKR activity

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15 sept. 2014
department

Virologie

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20 août 2013
publication

Human APOBEC3A isoforms translocate to the nucleus and induce DNA double strand breaks leading to cell stress and death

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20 juin 2013
publication

Efficient deamination of 5-methylcytidine and 5-substituted cytidine residues in DNA by human APOBEC3A cytidine deaminase

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19 sept. 2012
publication

Hyperediting of human T-cell leukemia virus type 2 and simian T-cell leukemia virus type 3 by the dsRNA adenosine deaminase ADAR-1

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13 sept. 2012
publication

Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A

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17 janv. 2012
publication

Evolution of the primate APOBEC3A cytidine deaminase gene and identification of related coding regions

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01 juin 2011
publication

Genetic editing of herpes simplex virus 1 and Epstein-Barr herpesvirus genomes by human APOBEC3 cytidine deaminases in culture and in vivo

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02 mars 2011
publication

Somatic hypermutation of human mitochondrial and nuclear DNA by APOBEC3 cytidine deaminases, a pathway for DNA catabolism

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15 déc. 2010
publication

Double-stranded RNA adenosine deaminase ADAR-1-induced hypermutated genomes among inactivated seasonal influenza and live attenuated measles virus vaccines

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28 mai 2010
publication

APOBEC1 and APOBEC3 cytidine deaminases as restriction factors for hepadnaviral genomes in non-humans in vivo

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27 mai 2010
publication

Massive APOBEC3 editing of hepatitis B viral DNA in cirrhosis

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21 oct. 2009
publication

Human APOBEC1 cytidine deaminase edits HBV DNA

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12 mars 2009
publication

Powerful mutators lurking in the genome

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26 janv. 2009
publication

Genetic editing of HBV DNA by monodomain human APOBEC3 cytidine deaminases and the recombinant nature of APOBEC3G

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01 nov. 2008
publication

Murine APOBEC1 is a powerful mutator of retroviral and cellular RNA in vitro and in vivo

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30 mai 2008
publication

Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs

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11 avr. 2008
publication

Evidence for editing of human papillomavirus DNA by APOBEC3 in benign and precancerous lesions

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14 févr. 2007
publication

Induction of mutations in Drosophila melanogaster gypsy retroelements by modulation of intracellular deoxynucleoside triphosphate pools in vivo

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08 sept. 2006
publication

Twin gradients in APOBEC3 edited HIV-1 DNA reflect the dynamics of lentiviral replication

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01 janv. 2006
publication

Restriction of foamy viruses by APOBEC cytidine deaminases

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01 sept. 2005
publication

Extensive editing of a small fraction of human T-cell leukemia virus type 1 genomes by four APOBEC3 cytidine deaminases

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01 janv. 2005
publication

Recovery of APOBEC3-edited human immunodeficiency virus G->A hypermutants by differential DNA denaturation PCR

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15 déc. 2004
publication

A universal primer set for PCR amplification of nuclear histone H4 genes from all animal species

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30 avr. 2004
publication

APOBEC3G is a single-stranded DNA cytidine deaminase and functions independently of HIV reverse transcriptase

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01 oct. 2003
publication

Death and the retrovirus

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01 avr. 2003
publication

Network analysis of human and simian immunodeficiency virus sequence sets reveals massive recombination resulting in shorter pathways

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01 nov. 2002
publication

Identification of a hepatitis B virus genome in wild chimpanzees (Pan troglodytes schweinfurthi) from East Africa indicates a wide geographical dispersion among equatorial African primates

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28 mai 2002
publication

Analysis of a library of macaque nuclear mitochondrial sequences confirms macaque origin of divergent sequences from old oral polio vaccine samples

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01 avr. 2002
publication

Sustained G–>A hypermutation during reverse transcription of an entire human immunodeficiency virus type 1 strain Vau group O genome

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