Ligne de temps
28 juil. 2015
08 juil. 2015
24 nov. 2014
publication
Histone methyltransferase inhibitors are orally bioavailable, fast-acting molecules with activity against different species causing malaria in humans
Lire plus09 juil. 2014
publication
Development of diaminoquinazoline histone lysine methyltransferase inhibitors as potent blood-stage antimalarial compounds
Lire plus29 juin 2014
publication
Exonuclease-mediated degradation of nascent RNA silences genes linked to severe malaria
Lire plus09 févr. 2014
publication
Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures
Lire plus07 janv. 2013
publication
Comprehensive histone phosphorylation analysis and identification of Pf14-3-3 protein as a histone H3 phosphorylation reader in malaria parasites
Lire plus24 sept. 2012
publication
Small-molecule histone methyltransferase inhibitors display rapid antimalarial activity against all blood stage forms in Plasmodium falciparum
Lire plus28 juil. 2009
publication
Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds
Lire plus19 mars 2009
publication
Host cell entry by apicomplexa parasites requires actin polymerization in the host cell
Lire plus04 juin 2008
publication
Triazolopyrimidine-based dihydroorotate dehydrogenase inhibitors with potent and selective activity against the malaria parasite Plasmodium falciparum
Lire plus26 févr. 2008
publication
Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies
Lire plus29 janv. 2008
publication
Analysis of flavin oxidation and electron-transfer inhibition in Plasmodium falciparum dihydroorotate dehydrogenase
Lire plus28 févr. 2007
publication
Detergent-dependent kinetics of truncated Plasmodium falciparum dihydroorotate dehydrogenase
Lire plus09 mars 2006
28 mars 2005
publication
High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase
Lire plus01 août 2003
publication
Dissociation of cGMP accumulation and relaxation in myometrial smooth muscle: effects of S-nitroso-N-acetylpenicillamine and 3-morpholinosyndonimine
Lire plus19 août 2002
01 sept. 2001
publication
NO-induced relaxation of labouring and non-labouring human myometrium is not mediated by cyclic GMP
Lire plus01 janv. 2001
publication
Secretion of a nucleoside diphosphate kinase (Nm23-H2) by cells from human breast, colon, pancreas and lung tumors
Lire plus01 janv. 2001
01 janv. 2001
publication