Ligne de temps
Jean-Christophe Barale
Chef(fe) de Groupe
05 avr. 2024
publication
Insights from structure-activity relationships and the binding mode of peptidic α-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1.
Lire plus13 mars 2024
publication
Prodomain-driven enzyme dimerization: a pH-dependent autoinhibition mechanism that controls Plasmodium Sub1 activity before merozoite egress.
Lire plus12 déc. 2022
publication
Prevalence and characterization of piperaquine, mefloquine and artemisinin derivatives triple-resistant Plasmodium falciparum in Cambodia.
Lire plus15 juil. 2022
14 juin 2022
publication
Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target.
Lire plus18 déc. 2015
16 juil. 2015
11 mai 2015
11 mai 2015
24 oct. 2014
publication
Computational design of protein-based inhibitors of Plasmodium vivax subtilisin-like 1 protease
Lire plus22 oct. 2014
publication
A small-molecule cell-based screen led to the identification of biphenylimidazoazines with highly potent and broad-spectrum anti-apicomplexan activity
Lire plus10 sept. 2014
publication
A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase
Lire plus21 mars 2014
publication
Cytometric measurement of in vitro inhibition of Plasmodium falciparum field isolates by drugs: a new approach for re-invasion inhibition study
Lire plus27 janv. 2014
publication
Whole Pichia pastoris yeast expressing measles virus nucleoprotein as a production and delivery system to multimerize Plasmodium antigens.
Lire plus18 déc. 2013
07 mai 2013
publication
In Silico screening on the three-dimensional model of the Plasmodium vivax SUB1 protease leads to the validation of a novel anti-parasite compound
Lire plus01 janv. 2013
publication
Screening and evaluation of inhibitors of Plasmodium falciparum merozoite egress and invasion using cytometry
Lire plus03 déc. 2012
publication
Reduced artemisinin susceptibility of Plasmodium falciparum ring stages in western Cambodia
Lire plus25 août 2011
publication
FLP/FRT-mediated conditional mutagenesis in pre-erythrocytic stages of Plasmodium berghei
Lire plus27 juil. 2011
publication
Computational reverse-engineering of a spider-venom derived peptide active against Plasmodium falciparum SUB1
Lire plus01 janv. 2011
18 mars 2010
publication
Centromeric plasmids and artificial chromosomes: new kids on the Plasmodium transfection block
Lire plus06 avr. 2009
publication
Drug inhibition of HDAC3 and epigenetic control of differentiation in Apicomplexa parasites
Lire plus01 oct. 2005
publication
Trypanosoma cruzi proline racemases are involved in parasite differentiation and infectivity
Lire plus01 mai 2005
publication
LANCL1, an erythrocyte protein recruited to the Maurer’s clefts during Plasmodium falciparum development
Lire plus04 mars 2005
publication
CyProQuant-PCR: a real time RT-PCR technique for profiling human cytokines, based on external RNA standards, readily automatable for clinical use
Lire plus01 janv. 2004
publication
Gene targeting demonstrates that the Plasmodium berghei subtilisin PbSUB2 is essential for red cell invasion and reveals spontaneous genetic recombination events
Lire plus01 oct. 2002
01 nov. 2000
publication
Pfsbp1, a Maurer’s cleft Plasmodium falciparum protein, is associated with the erythrocyte skeleton
Lire plus25 mai 1999
publication
Plasmodium falciparum subtilisin-like protease 2, a merozoite candidate for the merozoite surface protein 1-42 maturase
Lire plus16 févr. 1999
publication
Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization
Lire plus24 juil. 1998
publication
The LIM homeobox protein mLIM3/Lhx3 induces expression of the prolactin gene by a Pit-1/GHF-1-independent pathway in corticotroph AtT20 cells
Lire plus01 août 1997
publication
Plasmodium falciparum asparagine and aspartate rich protein 2 is an evolutionary conserved protein whose repeats identify a new family of parasite antigens
Lire plus01 août 1997
publication
Plasmodium falciparum AARP1, a giant protein containing repeated motifs rich in asparagine and aspartate residues, is associated with the infected erythrocyte membrane
Lire plus01 déc. 1994
publication
The mouse homeoprotein mLIM-3 is expressed early in cells derived from the neuroepithelium and persists in adult pituitary
Lire plus01 févr. 1994
01 juin 1993
publication
Isolation from a Plasmodium chabaudi chromosome 7 specific library of a novel gene encoding a protein with multiple GGMP repeats homologous to hsp70
Lire plus15 oct. 1992
publication
Plasmodium chabaudi p68 serine protease activity required for merozoite entry into mouse erythrocytes
Lire plus01 oct. 1992
publication
A Plasmodium falciparum gene coding for a 15-kilodalton antigen expressed in asexual stage parasites, gametocytes and gametes
Lire plus14 nov. 1991
publication
The C-terminal domain of RNA polymerase II of the malaria parasite Plasmodium berghei
Lire plus01 oct. 1991