Ligne de temps

David Bikard
Responsable de Structure
30 Apr 2020
publication

On-target activity predictions enable improved CRISPR-dCas9 screens in bacteria

Lire plus
10 Feb 2020
news

Atypical organizations and epistatic interactions of CRISPRs and cas clusters in genomes and their mobile genetic elements

Lire plus
24 Jan 2020
publication

Atypical organizations and epistatic interactions of CRISPRs and cas clusters in genomes and their mobile genetic elements

Lire plus
06 Jan 2020
publication

Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects

Lire plus
30 Sep 2019
event

Microbiology seminar: “CRISPR-Cas: acquired immunity in prokaryotes”

Lire plus
01 Aug 2019
publication

Gene silencing with CRISPRi in bacteria and optimization of dCas9 expression levels

Lire plus
26 Jul 2019
tool

crispr.pasteur.fr

Lire plus
13 May 2019
publication

Editing the microbiome the CRISPR way

Lire plus
13 May 2019
publication

A matter of background: DNA repair pathways as a possible cause for the sparse distribution of CRISPR-Cas systems in bacteria

Lire plus
20 Feb 2019
event

130 Years of Institut Pasteur: Celebrating Science

Lire plus
07 Nov 2018
publication

Genome-wide CRISPR-dCas9 screens in E. coli identify essential genes and phage host factors

Lire plus
15 May 2018
publication

A CRISPRi screen in E. coli reveals sequence-specific toxicity of dCas9

Lire plus
08 Mar 2018
publication

Tuning dCas9’s ability to block transcription enables robust, noiseless knockdown of bacterial genes

Lire plus
12 Dec 2017
publication

Inhibition of NHEJ repair by type II-A CRISPR-Cas systems in bacteria

Lire plus
27 Nov 2017
project

ERC starting grant – CRISPAIR: Study of the interplay between CRISPR interference and DNA repair pathways towards the development of novel CRISPR tools

Lire plus
15 Aug 2017
publication

PhageTerm: a tool for fast and accurate determination of phage termini and packaging mechanism using next-generation sequencing data

Lire plus
01 Jun 2017
publication

Using CRISPR-Cas systems as antimicrobials

Lire plus
28 Mar 2017
publication

Differences in Integron Cassette Excision Dynamics Shape a Trade-Off between Evolvability and Genetic Capacitance

Lire plus
10 Mar 2017
event

From phage defense to biotechnological tools: CRISPR and more

Lire plus
14 Feb 2017
software

PhageTerm

Lire plus
05 Jan 2017
publication

Mutations in Cas9 Enhance the Rate of Acquisition of Viral Spacer Sequences during the CRISPR-Cas Immune Response

Lire plus
23 Sep 2016
project

Prophage elements as a significant source of genetic diversity among epidemic C. difficile 027 strains

Lire plus
17 Sep 2016
publication

A Eukaryotic-like Serine/Threonine Kinase Protects Staphylococci against Phages

Lire plus
08 Apr 2016
publication

Consequences of Cas9 cleavage in the chromosome of Escherichia coli

Lire plus
27 Jul 2015
publication

Adapting to new threats: the generation of memory by CRISPR-Cas immune systems

Lire plus
02 Jul 2015
project

Studying and fighting pathogenic bacteria with the help of CRISPR

Lire plus
11 May 2015
team

Biologie de Synthèse

Lire plus
11 May 2015
team

Plasticité du Génome Bactérien

Lire plus
18 Feb 2015
publication

Cas9 specifies functional viral targets during CRISPR-Cas adaptation

Lire plus
05 Oct 2014
publication

Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials

Lire plus
31 Aug 2014
publication

Conditional tolerance of temperate phages via transcription-dependent CRISPR-Cas targeting

Lire plus
02 Dec 2013
publication

The integron integrase efficiently prevents the melting effect of Escherichia coli single-stranded DNA-binding protein on folded attC sites

Lire plus
01 Nov 2013
publication

Control of gene expression by CRISPR-Cas systems

Lire plus
12 Jun 2013
publication

Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system

Lire plus
29 Jan 2013
publication

RNA-guided editing of bacterial genomes using CRISPR-Cas systems

Lire plus
01 Jan 2013
publication

Shuffling of DNA cassettes in a synthetic integron

Lire plus
16 Aug 2012
publication

CRISPR interference can prevent natural transformation and virulence acquisition during in vivo bacterial infection

Lire plus
11 Nov 2011
publication

Innate and adaptive immunity in bacteria: mechanisms of programmed genetic variation to fight bacteriophages

Lire plus
01 Dec 2010
publication

Folded DNA in action: hairpin formation and biological functions in prokaryotes

Lire plus
13 Jul 2010
publication

Cellular pathways controlling integron cassette site folding

Lire plus
09 Jun 2010
publication

The synthetic integron: an in vivo genetic shuffling device

Lire plus
04 Sep 2009
publication

Structural features of single-stranded integron cassette attC sites and their role in strand selection

Lire plus
01 May 2008
publication

[First French team success during iGEM synthetic biology competition]

Lire plus