Ligne de temps
Max Bonomi
Responsable de Structure
08 sept. 2023
publication
Genotype and Phenotype Characterization of Rhinolophus sp. Sarbecoviruses from Vietnam: Implications for Coronavirus Emergence.
Lire plus24 mai 2023
05 avr. 2023
publication
SARS‐CoV‐2‐related bat virus behavior in human‐relevant models sheds light on the origin of COVID‐19
Lire plus30 mai 2022
publication
Determination of the structure and dynamics of the fuzzy coat of an amyloid fibril of IAPP using cryo-electron microscopy
Lire plus20 mai 2022
20 mai 2022
publication
HARIBOSS: a curated database of RNA-small molecules structures to aid rational drug design
Lire plus03 mai 2022
publication
Describing Inhibitor Specificity for the Amino Acid Transporter LAT1 from Metainference Simulations
Lire plus21 avr. 2022
14 avr. 2022
16 févr. 2022
publication
Discovery of bat coronaviruses close to SARS-CoV-2 and infectious for human cells.
Lire plus10 sept. 2021
publication
Rational design of ASCT2 inhibitors using an integrated experimental-computational approach
Lire plus08 sept. 2021
publication
Multi-replica biased sampling for photoisomerization processes in conjugated polymers
Lire plus03 mars 2021
03 mars 2021
03 févr. 2021
08 oct. 2020
publication
Small molecule sequestration of amyloid-β as a drug discovery strategy for Alzheimer’s disease
Lire plus04 févr. 2020
publication
What will computational modelling approaches have to say in the era of atomistic cryo-EM data?
Lire plus03 juil. 2019
01 juil. 2019
01 juil. 2019
01 juin 2019
09 mai 2019
01 févr. 2019
event
Determining the structure and dynamics of biological systems using integrative approaches
Lire plus24 janv. 2019
publication
A practical guide to the simultaneous determination of protein structure and dynamics using metainference
Lire plus10 janv. 2019
01 janv. 2019
publication
A Solid-State NMR and MD Study of the Structure of the Statherin Mutant SNa15 on Mineral Surfaces
Lire plus01 janv. 2019
publication
Bayesian Weighing of Electron Cryo-Microscopy Data for Integrative Structural Modeling
Lire plus23 nov. 2018
14 nov. 2018
02 nov. 2018
publication
A Versatile Computational Strategy To Characterize the Free-Energy Landscape of Excited States in Oligofluorenes
Lire plus06 sept. 2018
publication
Biasing Smarter, Not Harder, by Partitioning Collective Variables into Families in Parallel Bias Metadynamics
Lire plus25 juin 2018
publication
Reversible inhibition of the ClpP protease via an N-terminal conformational switch
Lire plus10 avr. 2018
publication
Simultaneous Determination of Protein Structure and Dynamics Using Cryo-Electron Microscopy
Lire plus26 mars 2018
publication
Structural Ensemble Modulation upon Small-Molecule Binding to Disordered Proteins
Lire plus01 janv. 2018
15 déc. 2017
31 oct. 2017
16 août 2017
publication
The molecular architecture of the yeast spindle pole body core determined by Bayesian integrative modeling
Lire plus22 juil. 2017
publication
Sequence Specificity in the Entropy-Driven Binding of a Small Molecule and a Disordered Peptide
Lire plus22 mars 2017
05 janv. 2017
26 août 2016
publication
Metadynamic metainference: Enhanced sampling of the metainference ensemble using metadynamics
Lire plus11 mars 2016
publication
Free energy landscapes of sodium ions bound to DMPC-cholesterol membrane surfaces at infinite dilution
Lire plus22 janv. 2016
12 nov. 2015
publication
The molecular architecture of the Dam1 kinetochore complex is defined by cross-linking based structural modelling
Lire plus09 oct. 2015
publication
Efficient Sampling of High-Dimensional Free-Energy Landscapes with Parallel Bias Metadynamics
Lire plus07 oct. 2015
publication
Ligand Discovery for the Alanine-Serine-Cysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening
Lire plus26 août 2015
20 août 2015
publication
Structural Model of the Bilitranslocase Transmembrane Domain Supported by NMR and FRET Data
Lire plus01 janv. 2015
01 janv. 2015
publication
Accuracy of current all-atom force-fields in modeling protein disordered states
Lire plus19 août 2014
publication
Determining protein complex structures based on a Bayesian model of in vivo Förster resonance energy transfer (FRET) data
Lire plus31 juil. 2014
publication
Cys-scanning disulfide crosslinking and bayesian modeling probe the transmembrane signaling mechanism of the histidine kinase, PhoQ
Lire plus12 avr. 2014
publication
Elucidating the mechanism of substrate recognition by the bacterial Hsp90 molecular chaperone
Lire plus06 févr. 2014
publication
The free energy profile of tubulin straight-bent conformational changes, with implications for microtubule assembly and drug discovery
Lire plus01 janv. 2014
01 janv. 2014
publication
Modeling of proteins and their assemblies with the Integrative Modeling Platform
Lire plus18 nov. 2013
19 mai 2013
publication
Structural basis for alternating access of a eukaryotic calcium/proton exchanger
Lire plus03 avr. 2013
31 mars 2013
29 août 2012
publication
High selectivity of the γ-aminobutyric acid transporter 2 (GAT-2, SLC6A13) revealed by structure-based approach
Lire plus20 juin 2012
publication
Efficient Simulation of Explicitly Solvated Proteins in the Well-Tempered Ensemble
Lire plus08 juin 2011
publication
A chirality-based metrics for free-energy calculations in biomolecular systems
Lire plus19 mai 2011
01 janv. 2011
13 oct. 2010
19 mai 2010
09 mars 2010
01 janv. 2010
14 mai 2009
publication
PLUMED: A portable plugin for free-energy calculations with molecular dynamics
Lire plus01 janv. 2009
publication
Reconstructing the equilibrium Boltzmann distribution from well-tempered metadynamics
Lire plus24 sept. 2008
publication
The unfolded ensemble and folding mechanism of the C-terminal GB1 beta-hairpin
Lire plus15 juin 2007