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Hélène Philippe

Désolé, cet article est seulement disponible en EN.

Four permanent positions in bioinformatics/biostatistics at Institut Pasteur – Hub fo Bioinformatics and Biostatistics

The Hub of Bioinformatics and Biostatistics, created in 2015 to provide support in these domains to the Units and Platforms of the Institut Pasteur, is recruiting four bioinformaticians to continue the support activities and […]

Benefits and risks associated with different uses of the COVID-19 vaccine Vaxzevria: a modelling study, France, May to September 2021.

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

Tran Kiem C, Andronico A, Bosetti P, Paireau J, Alter L, Boëlle PY, Fontanet A, Lévy-Bruhl D, Cauchemez S,

Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity.

Nature communications

Smith N, Possémé C, Bondet V, Sugrue J, Townsend L, Charbit B, Rouilly V, Saint-André V, Dott T, Pozo AR, Yatim N, Schwartz O, Cervantes-Gonzalez M, Ghosn J, Bastard P, Casanova JL, Szwebel TA, Terrier B, Conlon N, O'Farrelly C, Cheallaigh CN, Bourke NM, Duffy D

Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations: a systematic review.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Galmiche S, Luong Nguyen LB, Tartour E, de Lamballerie X, Wittkop L, Loubet P, Launay O,

Outpatient Antibiotic Prescriptions in France: Patients and Providers Characteristics and Impact of the COVID-19 Pandemic.

Antibiotics (Basel, Switzerland)

Bara W, Brun-Buisson C, Coignard B, Watier L

Risk factors associated with COVID-19-associated pulmonary aspergillosis in ICU patients: a French multicentric retrospective cohort.

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases

Dellière S, Dudoignon E, Fodil S, Voicu S, Collet M, Oillic PA, Salmona M, Dépret F, Ghelfenstein-Ferreira T, Plaud B, Chousterman B, Bretagne S, Azoulay E, Mebazaa A, Megarbane B, Alanio A,

Increased levels of GM-CSF and CXCL10 and low CD8+ memory stem T Cell count are markers of immunosenescence and severe COVID-19 in older people.

Immunity & ageing : I & A

Poisson J, El-Sissy C, Serret-Larmande A, Smith N, Lebraud M, Augy JL, Conti C, Gonnin C, Planquette B, Arlet JB, Hermann B, Charbit B, Pastre J, Devaux F, Ladavière C, Lim L, Ober P, Cannovas J, Biard L, Gulczynski MC, Blumenthal N, Péré H, Knosp C, Gey A, Benhamouda N, Murris J, Veyer D, Tartour E, Diehl JL, Duffy D, Paillaud E, Granier C

Compassionate Use of Hydroxychloroquine in Clinical Practice for Patients With Mild to Severe COVID-19 in a French University Hospital.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Paccoud O, Tubach F, Baptiste A, Bleibtreu A, Hajage D, Monsel G, Tebano G, Boutolleau D, Klement E, Godefroy N, Palich R, Itani O, Faiçal A, Valantin MA, Tubiana R, Burrel S, Calvez V, Caumes E, Marcelin AG, Pourcher V

Treatment of severe COVID-19 patients with either low- or high-volume of convalescent plasma versus standard of care: A multicenter Bayesian randomized open-label clinical trial (COOP-COVID-19-MCTI).

Lancet regional health. Americas

Song ATW, Rocha V, Mendrone-Júnior A, Calado RT, De Santis GC, Benites BD, Costa-Lima C, Vargas T, Marques LS, Fernandes JC, Breda FC, Wendel S, Fachini R, Rizzo LV, Kutner JM, Avelino-Silva VI, Machado RRG, Durigon EL, Chevret S, Kallas EG

A modelling study investigating short and medium-term challenges for COVID-19 vaccination: From prioritisation to the relaxation of measures.

EClinicalMedicine

Tran Kiem C, Massonnaud CR, Levy-Bruhl D, Poletto C, Colizza V, Bosetti P, Fontanet A, Gabet A, Olié V, Zanetti L, Boëlle PY, Crépey P, Cauchemez S,

Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial.

The Lancet. Respiratory medicine

Mapping the human genetic architecture of COVID-19.

Nature

Deciphering the state of immune silence in fatal COVID-19 patients.

Nature communications

Bost P, De Sanctis F, Canè S, Ugel S, Donadello K, Castellucci M, Eyal D, Fiore A, Anselmi C, Barouni RM, Trovato R, Caligola S, Lamolinara A, Iezzi M, Facciotti F, Mazzariol A, Gibellini D, De Nardo P, Tacconelli E, Gottin L, Polati E, Schwikowski B, Amit I, Bronte V,

Inherited and acquired errors of type I interferon immunity govern susceptibility to COVID-19 and multisystem inflammatory syndrome in children.

The Journal of allergy and clinical immunology

Bucciol G, , Meyts I

Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths.

Science immunology

Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Megarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs C, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Coulibaly B, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Nussbaum RL, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY, Shcherbina A, Lau YL, Leung D, Coulongeat M, Marlet J, Koning R, Reyes LF, Chauvineau-Grenier A, Venet F, Monneret G, Nussenzweig MC, Arrestier R, Boudhabhay I, Baris-Feldman H, Hagin D, Wauters J, Meyts I, Dyer AH, Kennelly SP, Bourke NM, Halwani R, Sharif-Askari NS, Dorgham K, Sallette J, Sedkaoui SM, AlKhater S, Rigo-Bonnin R, Morandeira F, Roussel L, Vinh DC, Ostrowski SR, Condino-Neto A, Prando C, Bonradenko A, Spaan AN, Gilardin L, Fellay J, Lyonnet S, Bilguvar K, Lifton RP, Mane S, , , , , , , , , , , , , , , , , , , , , Anderson MS, Boisson B, Béziat V, Zhang SY, Vandreakos E, Hermine O, Pujol A, Peterson P, Mogensen TH, Rowen L, Mond J, Debette S, de Lamballerie X, Duval X, Mentré F, Zins M, Soler-Palacin P, Colobran R, Gorochov G, Solanich X, Susen S, Martinez-Picado J, Raoult D, Vasse M, Gregersen PK, Piemonti L, Rodríguez-Gallego C, Notarangelo LD, Su HC, Kisand K, Okada S, Puel A, Jouanguy E, Rice CM, Tiberghien P, Zhang Q, Cobat A, Abel L, Casanova JL

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Differential efficacies of Cas nucleases on microsatellites involved in human disorders and associated off-target mutations.

Cotrimoxazole versus sulfadoxine-pyrimethamine for intermittent preventive treatment of malaria in HIV-infected pregnant women in Bangui, Central African Republic: a Pragmatic Randomized Controlled Trial.

Appels

Application as permanent staff scientist at Institut Pasteur

The Institut Pasteur is looking for a Scientific Director

Call for proposals | Grant: Auditory Infection and/or Immunity

Call for applications 2025 – Creation of new research groups at the Institut Pasteur

Événements

3 Événements à Venir

Calendrier

Aujourd'hui

23 Dec 2024

Voir tous

Department of Parasites and Insect Vectors Extraordinary Seminar : Systems Immunology at Spatial Resolution: AI-Driven Insights into Infectious Diseases”

Impact of foetal CMV infection on the developing brain and inner ear – Pierre GRESSENS

First international conference on CK1 PROTEIN KINASES: “FROM CELL SIGNALING TO THERAPEUTIC TARGETS IN HUMAN DISEASE” – Lorenzo Pinna, David Virshup , Nagi G Ayad , Kathy Gould , Nicolas Thomä , Carrie Partch , Stephanie Federico, Yinon Ben-Neriah , David Strutt , Stefan Knapp , Nicole Robbins , Volker Dötsch

Emplois

Emploi: Post-doctorant(e)

Post-doctoral position at Institut Pasteur in Paris

Immunologie Translationnelle

Emploi: Ingénieur(e) de Recherche

Bioinformatic engineer position at Institut Pasteur, Paris

Cellules dendritiques et immunité adaptative

Emploi: Ingénieur(e) de Recherche

Data manager/curator for genomic taxonomies of bacterial strains (12-month CDD)

Plateforme de Data Management

Emploi: Post-doctorant(e)

Postdoctoral position in the “Immunobiology and Therapy” Unit

Immunobiologie et Thérapie

Réseau

Publications

Cnidarian Cell Type Diversity and Regulation Revealed by Whole-Organism Single-Cell RNA-Seq

Analytical chemistry

eXL-MS: An Enhanced Cross-Linking Mass Spectrometry Workflow To Study Protein Complexes.

Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells.

Nature communications

Legionella para-effectors target chromatin and promote bacterial replication.

Actualités

The paper by Thomas Serrano, Stéphane Frémont, Frédérique Cuvelier and Arnaud Echar...

The paper by Thomas Serrano, Stéphane Frémont, Frédérique Cuvelier and Arnaud Echar...

Amazed project

The paper by Korenkova et al, (2024) was commented on in the journal Nature