• 2023
  Chen KY, Karuppusamy J, O'Neill MB, Opuu V, Bahin M, Foulon S, Ibanez P, Quintana-Murci L, Ozawa T, van der Werf S, Nghe P, Naffakh N, Griffiths A, Isel C , High-throughput droplet-based analysis of influenza A virus genetic reassortment by single-virus RNA sequencing., Proc Natl Acad Sci U S A 2023 Feb; 120(6): e2211098120.
• 2022
  Krischuns T, Isel C, Drncova P, Lukarska M, Pflug A, Paisant S, Navratil V, Cusack S, Naffakh N, , Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD., PLoS Pathog 2022 May; 18(5): e1010328.
• 2022
  Chen KY, Krischuns T, Varga LO, Harigua-Souiai E, Paisant S, Zettor A, Chiaravalli J, Delpal A, Courtney D, O'Brien A, Baker SC, Decroly E, Isel C, Agou F, Jacob Y, Blondel A, Naffakh N, , A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors., Antiviral Res 2022 May; 201(): 105272.
• 2021
  Fontanet A, Tondeur L, Grant R, Temmam S, Madec Y, Bigot T, Grzelak L, Cailleau I, Besombes C, Ungeheuer MN, Renaudat C, Perlaza BL, Arowas L, Jolly N, Pellerin SF, Kuhmel L, Staropoli I, Huon C, Chen KY, Crescenzo-Chaigne B, Munier S, Charneau P, Demeret C, Bruel T, Eloit M, Schwartz O, Hoen B, , SARS-CoV-2 infection in schools in a northern French city: a retrospective serological cohort study in an area of high transmission, France, January to April 2020., Euro Surveill 2021 04; 26(15): .
• 2021
  O'Neill MB, Quach H, Pothlichet J, Aquino Y, Bisiaux A, Zidane N, Deschamps M, Libri V, Hasan M, Zhang SY, Zhang Q, Matuozzo D, Cobat A, Abel L, Casanova JL, Naffakh N, Rotival M, Quintana-Murci L, , Single-Cell and Bulk RNA-Sequencing Reveal Differences in Monocyte Susceptibility to Influenza A Virus Infection Between Africans and Europeans., Front Immunol 2021 ; 12(): 768189.
• 2021
  Malausse N, van der Werf S, Naffakh N, Munier S, , Influenza B Virus Infection Is Enhanced Upon Heterotypic Co-infection With Influenza A Virus., Front Microbiol 2021 ; 12(): 631346.
• 2020
  Grzelak L, Temmam S, Planchais C, Demeret C, Tondeur L, Huon C, Guivel-Benhassine F, Staropoli I, Chazal M, Dufloo J, Planas D, Buchrieser J, Rajah MM, Robinot R, Porrot F, Albert M, Chen KY, Crescenzo-Chaigne B, Donati F, Anna F, Souque P, Gransagne M, Bellalou J, Nowakowski M, Backovic M, Bouadma L, Le Fevre L, Le Hingrat Q, Descamps D, Pourbaix A, Laouénan C, Ghosn J, Yazdanpanah Y, Besombes C, Jolly N, Pellerin-Fernandes S, Cheny O, Ungeheuer MN, Mellon G, Morel P, Rolland S, Rey FA, Behillil S, Enouf V, Lemaitre A, Créach MA, Petres S, Escriou N, Charneau P, Fontanet A, Hoen B, Bruel T, Eloit M, Mouquet H, Schwartz O, van der Werf S, , A comparison of four serological assays for detecting anti-SARS-CoV-2 antibodies in human serum samples from different populations., Sci Transl Med 2020 09; 12(559): .
• 2019
  Ashraf U, Tengo L, Le Corre L, Fournier G, Busca P, McCarthy AA, Rameix-Welti MA, Gravier-Pelletier C, Ruigrok RWH, Jacob Y, Vidalain PO, Pietrancosta N, Crépin T, Naffakh N, , Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy., Proc Natl Acad Sci U S A 2019 May; 116(22): 10968-10977.
• 2018
  Ashraf U, Benoit-Pilven C, Lacroix V, Navratil V, Naffakh N, Advances in Analyzing Virus-Induced Alterations of Host Cell Splicing, Trends Microbiol. 2019 Mar;27(3):268-281.
• 2018
  Pagani I, Di Pietro A, Oteiza A, Ghitti M, Mechti N, Naffakh N, Vicenzi E, Mutations Conferring Increased Sensitivity to Tripartite Motif 22 Restriction Accumulated Progressively in the Nucleoprotein of Seasonal Influenza A (H1N1) Viruses between 1918 and 2009, mSphere 2018 04;3(2).
• 2018
  Sachse M, de Castro IF, Fournier G, Naffakh N, Risco C, Metal-Tagging Transmission Electron Microscopy and Immunogold Labeling on Tokuyasu Cryosections to Image Influenza A Virus Ribonucleoprotein Transport and Packaging, Methods Mol. Biol. 2018;1836:281-301.
• 2017
  Biquand E, Poirson J, Karim M, Declercq M, Malausse N, Cassonnet P, Barbezange C, Straub ML, Jones L, Munier S, Naffakh N, van der Werf S, Jacob Y, Masson M, Demeret C, Comparative Profiling of Ubiquitin Proteasome System Interplay with Influenza A Virus PB2 Polymerase Protein Recapitulating Virus Evolution in Humans, mSphere 2017 Nov-Dec;2(6).
• 2017
  de Castro Martin IF, Fournier G, Sachse M, Pizarro-Cerda J, Risco C, Naffakh N, Influenza virus genome reaches the plasma membrane via a modified endoplasmic reticulum and Rab11-dependent vesicles, Nat Commun 2017 11;8(1):1396.
• 2016
  Lukarska M, Fournier G, Pflug A, Resa-Infante P, Reich S, Naffakh N, Cusack S, Structural basis of an essential interaction between influenza polymerase and Pol II CTD, Nature 2017 01;541(7635):117-121.
• 2016
  Quach H, Rotival M, Pothlichet J, Loh YE, Dannemann M, Zidane N, Laval G, Patin E, Harmant C, Lopez M, Deschamps M, Naffakh N, Duffy D, Coen A, Leroux-Roels G, Clément F, Boland A, Deleuze JF, Kelso J, Albert ML, Quintana-Murci L, Genetic Adaptation and Neandertal Admixture Shaped the Immune System of Human Populations, Cell 2016 Oct;167(3):643-656.e17.
• 2016
  Diot C, Fournier G, Dos Santos M, Magnus J, Komarova A, van der Werf S, Munier S, Naffakh N, , Influenza A Virus Polymerase Recruits the RNA Helicase DDX19 to Promote the Nuclear Export of Viral mRNAs., Sci Rep 2016 Sep; 6(): 33763.
• 2016
  Isel C, Munier S, Naffakh N, Experimental Approaches to Study Genome Packaging of Influenza A Viruses, Viruses 2016 08;8(8).
• 2016
  Avilov S, Magnus J, Cusack S, Naffakh N, Time-Resolved Visualisation of Nearly-Native Influenza A Virus Progeny Ribonucleoproteins and Their Individual Components in Live Infected Cells, PLoS ONE 2016;11(3):e0149986.
• 2016
  Blanc F, Furio L, Moisy D, Yen HL, Chignard M, Letavernier E, Naffakh N, Mok CK, Si-Tahar M, Targeting host calpain proteases decreases influenza A virus infection, Am. J. Physiol. Lung Cell Mol. Physiol. 2016 04;310(7):L689-99.
• 2015
  Da Costa B, Sausset A, Munier S, Ghounaris A, Naffakh N, Le Goffic R, Delmas B, Temperature-Sensitive Mutants in the Influenza A Virus RNA Polymerase: Alterations in the PA Linker Reduce Nuclear Targeting of the PB1-PA Dimer and Result in Viral Attenuation, J. Virol. 2015 Jun;89(12):6376-90.
• 2014
  Fournier G, Chiang C, Munier S, Tomoiu A, Demeret C, Vidalain PO, Jacob Y, Naffakh N, Recruitment of RED-SMU1 complex by Influenza A Virus RNA polymerase to control Viral mRNA splicing, PLoS Pathog. 2014 Jun;10(6):e1004164.
• 2014
  Trapp S, Soubieux D, Marty H, Esnault E, Hoffmann TW, Chandenier M, Lion A, Kut E, Quéré P, Larcher T, Ledevin M, Munier S, Naffakh N, Marc D, Shortening the unstructured, interdomain region of the non-structural protein NS1 of an avian H1N1 influenza virus increases its replication and pathogenicity in chickens, J. Gen. Virol. 2014 Jun;95(Pt 6):1233-43.
• 2013
  Desdouits M, Munier S, Prevost MC, Jeannin P, Butler-Browne G, Ozden S, Gessain A, Van Der Werf S, Naffakh N, Ceccaldi PE, Productive infection of human skeletal muscle cells by pandemic and seasonal influenza A(H1N1) viruses, PLoS ONE 2013;8(11):e79628.
• 2013
  Berre S, Gaudin R, Cunha de Alencar B, Desdouits M, Chabaud M, Naffakh N, Rabaza-Gairi M, Gobert FX, Jouve M, Benaroch P, CD36-specific antibodies block release of HIV-1 from infected primary macrophages and its transmission to T cells, J. Exp. Med. 2013 Nov;210(12):2523-38.
• 2013
  Munier S, Rolland T, Diot C, Jacob Y, Naffakh N, , Exploration of binary virus-host interactions using an infectious protein complementation assay., Mol Cell Proteomics 2013 Oct; 12(10): 2845-55.
• 2012
  Rudrawar S, Kerry PS, Rameix-Welti MA, Maggioni A, Dyason JC, Rose FJ, van der Werf S, Thomson RJ, Naffakh N, Russell RJ, von Itzstein M, , Synthesis and evaluation of novel 3-C-alkylated-Neu5Ac2en derivatives as probes of influenza virus sialidase 150-loop flexibility., Org Biomol Chem 2012 Nov; 10(43): 8628-39.
• 2012
  Avilov SV, Moisy D, Naffakh N, Cusack S, Influenza A virus progeny vRNP trafficking in live infected cells studied with the virus-encoded fluorescently tagged PB2 protein, Vaccine 2012 Dec;30(51):7411-7.
• 2012
  Terrier O, Moules V, Carron C, Cartet G, Frobert E, Yver M, Traversier A, Wolff T, Riteau B, Naffakh N, Lina B, Diaz JJ, Rosa-Calatrava M, The influenza fingerprints: NS1 and M1 proteins contribute to specific host cell ultrastructure signatures upon infection by different influenza A viruses, Virology 2012 Oct;432(1):204-18.
• 2012
  Moisy D, Avilov SV, Jacob Y, Laoide BM, Ge X, Baudin F, Naffakh N, Jestin JL, HMGB1 protein binds to influenza virus nucleoprotein and promotes viral replication, J. Virol. 2012 Sep;86(17):9122-33.
• 2011
  Avilov SV, Moisy D, Munier S, Schraidt O, Naffakh N, Cusack S, Replication-competent influenza A virus that encodes a split-green fluorescent protein-tagged PB2 polymerase subunit allows live-cell imaging of the virus life cycle, J. Virol. 2012 Feb;86(3):1433-48.
• 2011
  Pelletier I, Rousset D, Enouf V, , Colbere-Garapin F, van der Werf S, Naffakh N, Highly heterogeneous temperature sensitivity of 2009 pandemic influenza A(H1N1) viral isolates, northern France, Euro Surveill. 2011 Oct;16(43).
• 2011
  Hoffmann TW, Munier S, Larcher T, Soubieux D, Ledevin M, Esnault E, Tourdes A, Croville G, Guérin JL, Quéré P, Volmer R, Naffakh N, Marc D, Length variations in the NA stalk of an H7N1 influenza virus have opposite effects on viral excretion in chickens and ducks, J. Virol. 2012 Jan;86(1):584-8.
• 2011
  Chase GP, Rameix-Welti MA, Zvirbliene A, Zvirblis G, Götz V, Wolff T, Naffakh N, Schwemmle M, , Influenza virus ribonucleoprotein complexes gain preferential access to cellular export machinery through chromatin targeting., PLoS Pathog 2011 Sep; 7(9): e1002187.
• 2011
  Ge X, Rameix-Welti MA, Gault E, Chase G, dos Santos Afonso E, Picard D, Schwemmle M, Naffakh N, , Influenza virus infection induces the nuclear relocalization of the Hsp90 co-chaperone p23 and inhibits the glucocorticoid receptor response., PLoS One 2011 ; 6(8): e23368.
• 2011
  Robb NC, Chase G, Bier K, Vreede FT, Shaw PC, Naffakh N, Schwemmle M, Fodor E, The influenza A virus NS1 protein interacts with the nucleoprotein of viral ribonucleoprotein complexes, J. Virol. 2011 May;85(10):5228-31.
• 2011
  Naffakh N, Shih SR, Confronting influenza virus: a common but ever-changing pathogen, Microbes Infect. 2011 May;13(5):468-9.
• 2011
  Rameix-Welti MA, Munier S, Le Gal S, Cuvelier F, Agou F, Enouf V, Naffakh N, van der Werf S, , Neuraminidase of 2007-2008 influenza A(H1N1) viruses shows increased affinity for sialic acids due to the D344N substitution., Antivir Ther 2011 ; 16(4): 597-603.
• 2010
  Rudrawar S, Dyason JC, Rameix-Welti MA, Rose FJ, Kerry PS, Russell RJ, van der Werf S, Thomson RJ, Naffakh N, von Itzstein M, , Novel sialic acid derivatives lock open the 150-loop of an influenza A virus group-1 sialidase., Nat Commun 2010 Nov; 1(): 113.
• 2010
  Moules V, Ferraris O, Terrier O, Giudice E, Yver M, Rolland JP, Bouscambert-Duchamp M, Bergeron C, Ottmann M, Fournier E, Traversier A, Boule C, Rivoire A, Lin Y, Hay A, Valette M, Marquet R, Rosa-Calatrava M, Naffakh N, Schoehn G, Thomas D, Lina B, In vitro characterization of naturally occurring influenza H3NA- viruses lacking the NA gene segment: toward a new mechanism of viral resistance?, Virology 2010 Sep;404(2):215-24.
• 2010
  Munier S, Moisy D, Marc D, Naffakh N, [Interspecies transmission, adaptation to humans and pathogenicity of animal influenza viruses], Pathol. Biol. 2010 Apr;58(2):e59-68.
• 2009
  Su B, Wurtzer S, Rameix-Welti MA, Dwyer D, van der Werf S, Naffakh N, Clavel F, Labrosse B, , Enhancement of the influenza A hemagglutinin (HA)-mediated cell-cell fusion and virus entry by the viral neuraminidase (NA)., PLoS One 2009 Dec; 4(12): e8495.
• 2009
  Munier S, Larcher T, Cormier-Aline F, Soubieux D, Su B, Guigand L, Labrosse B, Cherel Y, Quéré P, Marc D, Naffakh N, A genetically engineered waterfowl influenza virus with a deletion in the stalk of the neuraminidase has increased virulence for chickens, J. Virol. 2010 Jan;84(2):940-52.
• 2009
  Rameix-Welti MA, Zarantonelli ML, Giorgini D, Ruckly C, Marasescu M, van der Werf S, Alonso JM, Naffakh N, Taha MK, , Influenza A virus neuraminidase enhances meningococcal adhesion to epithelial cells through interaction with sialic acid-containing meningococcal capsules., Infect Immun 2009 Sep; 77(9): 3588-95.
• 2009
  Naffakh N, van der Werf S, April 2009: an outbreak of swine-origin influenza A(H1N1) virus with evidence for human-to-human transmission, Microbes Infect. 2009 Jul-Aug;11(8-9):725-8.
• 2009
  Matsuoka Y, Swayne DE, Thomas C, Rameix-Welti MA, Naffakh N, Warnes C, Altholtz M, Donis R, Subbarao K, , Neuraminidase stalk length and additional glycosylation of the hemagglutinin influence the virulence of influenza H5N1 viruses for mice., J Virol 2009 May; 83(9): 4704-8.
• 2008
  Rameix-Welti MA, Tomoiu A, Dos Santos Afonso E, van der Werf S, Naffakh N, , Avian Influenza A virus polymerase association with nucleoprotein, but not polymerase assembly, is impaired in human cells during the course of infection., J Virol 2009 Feb; 83(3): 1320-31.
• 2008
  Naffakh N, Tomoiu A, Rameix-Welti MA, van der Werf S, , Host restriction of avian influenza viruses at the level of the ribonucleoproteins., Annu Rev Microbiol 2008 ; 62(): 403-24.
• 2007
  Gog JR, Afonso Edos S, Dalton RM, Leclercq I, Tiley L, Elton D, von Kirchbach JC, Naffakh N, Escriou N, Digard P, Codon conservation in the influenza A virus genome defines RNA packaging signals, Nucleic Acids Res. 2007;35(6):1897-907.
• 2007
  Labadie K, Dos Santos Afonso E, Rameix-Welti MA, van der Werf S, Naffakh N, , Host-range determinants on the PB2 protein of influenza A viruses control the interaction between the viral polymerase and nucleoprotein in human cells., Virology 2007 Jun; 362(2): 271-82.
• 2007
  Medeiros R, Rameix-Welti MA, Lorin V, Ribaud P, Manuguerra JC, Socie G, Scieux C, Naffakh N, van der Werf S, , Failure of zanamivir therapy for pneumonia in a bone-marrow transplant recipient infected by a zanamivir-sensitive influenza A (H1N1) virus., Antivir Ther 2007 ; 12(4): 571-6.
• 2006
  Rameix-Welti MA, Agou F, Buchy P, Mardy S, Aubin JT, Véron M, van der Werf S, Naffakh N, , Natural variation can significantly alter the sensitivity of influenza A (H5N1) viruses to oseltamivir., Antimicrob Agents Chemother 2006 Nov; 50(11): 3809-15.
• 2005
  Vieira Machado A, Naffakh N, Gerbaud S, van der Werf S, Escriou N, Recombinant influenza A viruses harboring optimized dicistronic NA segment with an extended native 5′ terminal sequence: induction of heterospecific B and T cell responses in mice, Virology 2006 Feb;345(1):73-87.
• 2005
  Massin P, Rodrigues P, Marasescu M, van der Werf S, Naffakh N, Cloning of the chicken RNA polymerase I promoter and use for reverse genetics of influenza A viruses in avian cells, J. Virol. 2005 Nov;79(21):13811-6.
• 2005
  Dos Santos Afonso E, Escriou N, Leclercq I, van der Werf S, Naffakh N, The generation of recombinant influenza A viruses expressing a PB2 fusion protein requires the conservation of a packaging signal overlapping the coding and noncoding regions at the 5′ end of the PB2 segment, Virology 2005 Oct;341(1):34-46.
• 2004
  Medeiros R, Naffakh N, Manuguerra JC, van der Werf S, Binding of the hemagglutinin from human or equine influenza H3 viruses to the receptor is altered by substitutions at residue 193, Arch. Virol. 2004 Aug;149(8):1663-71.
• 2003
  Machado AV, Naffakh N, van der Werf S, Escriou N, Expression of a foreign gene by stable recombinant influenza viruses harboring a dicistronic genomic segment with an internal promoter, Virology 2003 Aug;313(1):235-49.
• 2002
  Crescenzo-Chaigne B, van der Werf S, Naffakh N, Differential effect of nucleotide substitutions in the 3′ arm of the influenza A virus vRNA promoter on transcription/replication by avian and human polymerase complexes is related to the nature of PB2 amino acid 627, Virology 2002 Nov;303(2):240-52.
• 2001
  Medeiros R, Escriou N, Naffakh N, Manuguerra JC, van der Werf S, Hemagglutinin residues of recent human A(H3N2) influenza viruses that contribute to the inability to agglutinate chicken erythrocytes, Virology 2001 Oct;289(1):74-85.
• 2001
  Naffakh N, Massin P, van der Werf S, The transcription/replication activity of the polymerase of influenza A viruses is not correlated with the level of proteolysis induced by the PA subunit, Virology 2001 Jul;285(2):244-52.
• 2001
  Massin P, van der Werf S, Naffakh N, Residue 627 of PB2 is a determinant of cold sensitivity in RNA replication of avian influenza viruses, J. Virol. 2001 Jun;75(11):5398-404.
• 2000
  Naffakh N, Massin P, Escriou N, Crescenzo-Chaigne B, van der Werf S, Genetic analysis of the compatibility between polymerase proteins from human and avian strains of influenza A viruses, J. Gen. Virol. 2000 May;81(Pt 5):1283-91.
• 1999
  Crescenzo-Chaigne B, Naffakh N, van der Werf S, Comparative analysis of the ability of the polymerase complexes of influenza viruses type A, B and C to assemble into functional RNPs that allow expression and replication of heterotypic model RNA templates in vivo, Virology 1999 Dec;265(2):342-53.
• 1997
  Bohl D, Naffakh N, Heard JM, Long-term control of erythropoietin secretion by doxycycline in mice transplanted with engineered primary myoblasts, Nat. Med. 1997 Mar;3(3):299-305.
• 1996
  Naffakh N, Danos O, Gene transfer for erythropoiesis enhancement, Mol Med Today 1996 Aug;2(8):343-8.
• 1996
  Naffakh N, Pinset C, Montarras D, Li Z, Paulin D, Danos O, Heard JM, Long-term secretion of therapeutic proteins from genetically modified skeletal muscles, Hum. Gene Ther. 1996 Jan;7(1):11-21.
• 1995
  Naffakh N, Henri A, Villeval JL, Rouyer-Fessard P, Moullier P, Blumenfeld N, Danos O, Vainchenker W, Heard JM, Beuzard Y, Sustained delivery of erythropoietin in mice by genetically modified skin fibroblasts, Proc. Natl. Acad. Sci. U.S.A. 1995 Apr;92(8):3194-8.
• 1995
  Naffakh N, Moullier P, Salvetti A, Bohl D, Danos O, Heard JM, Delivery of therapeutic proteins from genetically-modified cells, Restor. Neurol. Neurosci. 1995 Jan;8(1):67-9.
• 1994
  Naffakh N, Bohl D, Salvetti A, Moullier P, Danos O, Heard JM, Gene therapy for lysosomal disorders, Nouv Rev Fr Hematol 1994;36 Suppl 1:S11-6.
• 1993
  Naffakh N, Pinset C, Montarras D, Pastoret C, Danos O, Heard JM, Transplantation of adult-derived myoblasts in mice following gene transfer, Neuromuscul. Disord. 1993 Sep-Nov;3(5-6):413-7.
• 1993
  Maréchal V, Naffakh N, Danos O, Heard JM, Disappearance of lysosomal storage in spleen and liver of mucopolysaccharidosis VII mice after transplantation of genetically modified bone marrow cells, Blood 1993 Aug;82(4):1358-65.
• 1993
  Naffakh N, Le Gall S, Danos O, Heard JM, Cournot G, Motoyoshi K, Vilmer E, Macrophage colony-stimulating factor: serum levels and cDNA structure in malignant osteopetrosis, Blood 1993 May;81(10):2817-8.
• 1991
  Moullier P, Marechal V, Ferry N, Naffakh N, Heard JM, Danos O, Gene transfer to somatic tissues using retroviral vectors, Nouv Rev Fr Hematol 1991;33(6):493-5.