• 2025
  L. Gorline, F. Luiz Rosa do Carmo, P. Bourdely, J. Bornères, N. Vaudiau, A. Semervil, M. Vetillard, A. Ok, O Fiquet, M. Andrade, H. Theobald, M. Collin, J. Calmette, G. Anselmi, F. Fico, F. Ginhoux, L. Saveanu, J. Helft, M. Dalod, M. Dusseaux, J. P. Di Santo, S. Hugues, P. Guermonprez1,2,3* , Intra-tumoral delivery of FLT3L with CXCR3/CCR5 ligands promotes XCR1+ DC1 infiltration and activates anti-tumor immunity, Biorxiv Preprint.
• 2025
  Tandon N., Gutiérrez-Martínez E., Bourdely P., Anselmi G., Denisot J., Gerber Y., Helft J., Bens M., Saveanu L., Guermonprez P. , The Rab32 small GTPase is required for efficient cross-priming of CD8+ T cells against cell-associated antigens by XCR1+ type 1 DCs in vivo, Biorxiv - Preprint Article.
• 2025
  Vaudiau N., Bourdely P., Ok A., Semitekolou M., Gorline L., Savoldelli R., Gerber-Ferder Y., Luiz Rosa do Carmo F., Semervil A., Vétillard M., Rood A., Bouallègue S., Pamboukas K., Borneres J., Darasse-Jèze G., L Gautier E., Dalod M., Tartour E., Bergsbaken T., P J M Van Gisbergen K., Hodivala-Dilke K., Saveanu L., Helft J., Benvenuti F., Guermonprez P., XCR1+ and IRF4+ migratory dendritic cells cooperate for the cross-priming of intratumoral CD8+ T cells with a tissue-resident memory phenotype, Research Square - Preprint Article.
• 2024
  López L, Morosi LG, La Terza F, Bourdely P, Rospo G, Amadio R, Piperno GM, Russo V, Volponi C, Vodret S, Joshi S, Giannese F, Lazarevic D, Germano G, Stoitzner P, Bardelli A, Dalod M, Pace L, Caronni N, Guermonprez P, Benvenuti F, Dendritic cell-targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors., Nat Commun 2024 Mar; 15(1): 2280.
• 2023
  Régnier P, Vetillard M, Bansard A, Pierre E, Li X, Cagnard N, Gautier EL, Guermonprez P, Manoury B, Podsypanina K, Darrasse-Jèze G, FLT3L-dependent dendritic cells control tumor immunity by modulating Treg and NK cell homeostasis., Cell Rep Med 2023 Dec; 4(12): 101256.
• 2023
  Gerber-Ferder Y, Cosgrove J, Duperray-Susini A, Missolo-Koussou Y, Dubois M, Stepaniuk K, Pereira-Abrantes M, Sedlik C, Lameiras S, Baulande S, Bendriss-Vermare N, Guermonprez P, Passaro D, Perié L, Piaggio E, Helft J, Breast cancer remotely imposes a myeloid bias on haematopoietic stem cells by reprogramming the bone marrow niche., Nat Cell Biol 2023 Dec; 25(12): 1736-1745.
• 2023
  Liu Z, Wang H, Li Z, Dress RJ, Zhu Y, Zhang S, De Feo D, Kong WT, Cai P, Shin A, Piot C, Yu J, Gu Y, Zhang M, Gao C, Chen L, Wang H, Vétillard M, Guermonprez P, Kwok I, Ng LG, Chakarov S, Schlitzer A, Becher B, Dutertre CA, Su B, Ginhoux F, Dendritic cell type 3 arises from Ly6C+ monocyte-dendritic cell progenitors., Immunity 2023 Aug; 56(8): 1761-1777.e6.
• 2023
  Gerber-Ferder Y, Bourdely P, Vetillard M, Guermonprez P, Helft J, In Vitro Generation of Murine Bone Marrow-Derived Dendritic Cells., Methods Mol Biol 2023 ; 2618(): 83-92.
• 2023
  Bourdely P, Savoldelli R, Vetillard M, Anselmi G, Helft J, Guermonprez P, In Vitro Generation of Human Dendritic Cell Subsets from CD34+ Cord Blood Progenitors., Methods Mol Biol 2023 ; 2618(): 121-132.
• 2022
  Nalio Ramos R, Missolo-Koussou Y, Gerber-Ferder Y, Bromley CP, Bugatti M, Núñez NG, Tosello Boari J, Richer W, Menger L, Denizeau J, Sedlik C, Caudana P, Kotsias F, Niborski LL, Viel S, Bohec M, Lameiras S, Baulande S, Lesage L, Nicolas A, Meseure D, Vincent-Salomon A, Reyal F, Dutertre CA, Ginhoux F, Vimeux L, Donnadieu E, Buttard B, Galon J, Zelenay S, Vermi W, Guermonprez P, Piaggio E, Helft J, Tissue-resident FOLR2+ macrophages associate with CD8+ T cell infiltration in human breast cancer., Cell 2022 Mar; 185(7): 1189-1207.e25.
• 2022
  Rivera CA, Randrian V, Richer W, Gerber-Ferder Y, Delgado MG, Chikina AS, Frede A, Sorini C, Maurin M, Kammoun-Chaari H, Parigi SM, Goudot C, Cabeza-Cabrerizo M, Baulande S, Lameiras S, Guermonprez P, Reis e Sousa C, Lecuit M, Moreau HD, Helft J, Vignjevic DM, Villablanca EJ, Lennon-Duménil AM, Epithelial colonization by gut dendritic cells promotes their functional diversification., Immunity 2022 Jan; 55(1): 129-144.e8.
• 2021
  Caronni N, Piperno GM, Simoncello F, Romano O, Vodret S, Yanagihashi Y, Dress R, Dutertre CA, Bugatti M, Bourdeley P, Del Prete A, Schioppa T, Mazza EMC, Collavin L, Zacchigna S, Ostuni R, Guermonprez P, Vermi W, Ginhoux F, Bicciato S, Nagata S, Benvenuti F, TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses., Nat Commun 2021 Apr; 12(1): 2237.
• 2021
  Pievani A, Savoldelli R, Poelchen J, Mattioli E, Anselmi G, Girardot A, Utikal J, Bourdely P, Serafini M, Guermonprez P, Harnessing Mesenchymal Stromal Cells for the Engineering of Human Hematopoietic Niches., Front Immunol 2021 ; 12(): 631279.
• 2020
  Anselmi G, Helft J, Guermonprez P, Development and function of human dendritic cells in humanized mice models., Mol Immunol 2020 Sep; 125(): 151-161.
• 2020
  Bourdely P, Anselmi G, Vaivode K, Ramos RN, Missolo-Koussou Y, Hidalgo S, Tosselo J, Nuñez N, Richer W, Vincent-Salomon A, Saxena A, Wood K, Lladser A, Piaggio E, Helft J, Guermonprez P, Transcriptional and Functional Analysis of CD1c+ Human Dendritic Cells Identifies a CD163+ Subset Priming CD8+CD103+ T Cells., Immunity 2020 Aug; 53(2): 335-352.e8.
• 2020
  Evnouchidou I, Chappert P, Benadda S, Zucchetti A, Weimershaus M, Bens M, Caillens V, Koumantou D, Lotersztajn S, van Endert P, Davoust J, Guermonprez P, Hivroz C, Gross DA, Saveanu L, IRAP-dependent endosomal T cell receptor signalling is essential for T cell responses., Nat Commun 2020 Jun; 11(1): 2779.
• 2020
  Anselmi G, Vaivode K, Dutertre CA, Bourdely P, Missolo-Koussou Y, Newell E, Hickman O, Wood K, Saxena A, Helft J, Ginhoux F, Guermonprez P, Engineered niches support the development of human dendritic cells in humanized mice., Nat Commun 2020 Apr; 11(1): 2054.
• 2020
  Purvis HA, Clarke F, Montgomery AB, Colas C, Bibby JA, Cornish GH, Dai X, Dudziak D, Rawlings DJ, Zamoyska R, Guermonprez P, Cope AP, Phosphatase PTPN22 Regulates Dendritic Cell Homeostasis and cDC2 Dependent T Cell Responses., Front Immunol 2020 ; 11(): 376.
• 2020
  Ginhoux F, Mildner A, Gautier EL, Schlitzer A, Jakubzick C, Varol C, Bain C, Guermonprez P, Editorial: Monocyte Heterogeneity and Function., Front Immunol 2020 ; 11(): 626725.
• 2019
  Guermonprez P, Helft J, Inflammasome activation: a monocyte lineage privilege., Nat Immunol 2019 Apr; 20(4): 383-385.
• 2019
  Guermonprez P, Gerber-Ferder Y, Vaivode K, Bourdely P, Helft J, Origin and development of classical dendritic cells., Int Rev Cell Mol Biol 2019 ; 349(): 1-54.
• 2018
  Clarke F, Purvis HA, Sanchez-Blanco C, Gutiérrez-Martinez E, Cornish GH, Zamoyska R, Guermonprez P, Cope AP, The protein tyrosine phosphatase PTPN22 negatively regulates presentation of immune complex derived antigens., Sci Rep 2018 Aug; 8(1): 12692.
• 2017
  Péan CB, Schiebler M, Tan SW, Sharrock JA, Kierdorf K, Brown KP, Maserumule MC, Menezes S, Pilátová M, Bronda K, Guermonprez P, Stramer BM, Andres Floto R, Dionne MS, Regulation of phagocyte triglyceride by a STAT-ATG2 pathway controls mycobacterial infection., Nat Commun 2017 Mar; 8(): 14642.
• 2017
  Clarke F, Jordan CK, Gutiérrez-Martinez E, Bibby JA, Sanchez-Blanco C, Cornish GH, Dai X, Rawlings DJ, Zamoyska R, Guermonprez P, Cope AP, Purvis HA, Protein tyrosine phosphatase PTPN22 is dispensable for dendritic cell antigen processing and promotion of T-cell activation by dendritic cells., PLoS One 2017 ; 12(10): e0186625.
• 2016
  Menezes S, Melandri D, Anselmi G, Perchet T, Loschko J, Dubrot J, Patel R, Gautier EL, Hugues S, Longhi MP, Henry JY, Quezada SA, Lauvau G, Lennon-Duménil AM, Gutiérrez-Martínez E, Bessis A, Gomez-Perdiguero E, Jacome-Galarza CE, Garner H, Geissmann F, Golub R, Nussenzweig MC, Guermonprez P, The Heterogeneity of Ly6Chi Monocytes Controls Their Differentiation into iNOS+ Macrophages or Monocyte-Derived Dendritic Cells., Immunity 2016 Dec; 45(6): 1205-1218.
• 2016
  Loschko J, Rieke GJ, Schreiber HA, Meredith MM, Yao KH, Guermonprez P, Nussenzweig MC, Inducible targeting of cDCs and their subsets in vivo., J Immunol Methods 2016 Jul; 434(): 32-8.
• 2015
  Adiko AC, Babdor J, Gutiérrez-Martínez E, Guermonprez P, Saveanu L, Intracellular Transport Routes for MHC I and Their Relevance for Antigen Cross-Presentation., Front Immunol 2015 ; 6(): 335.
• 2015
  Gutiérrez-Martínez E, Planès R, Anselmi G, Reynolds M, Menezes S, Adiko AC, Saveanu L, Guermonprez P, Cross-Presentation of Cell-Associated Antigens by MHC Class I in Dendritic Cell Subsets., Front Immunol 2015 ; 6(): 363.
• 2014
  Colas C, Menezes S, Gutiérrez-Martínez E, Péan CB, Dionne MS, Guermonprez P, An improved flow cytometry assay to monitor phagosome acidification., J Immunol Methods 2014 Oct; 412(): 1-13.
• 2013
  Schreiber HA, Loschko J, Karssemeijer RA, Escolano A, Meredith MM, Mucida D, Guermonprez P, Nussenzweig MC, Intestinal monocytes and macrophages are required for T cell polarization in response to Citrobacter rodentium., J Exp Med 2013 Sep; 210(10): 2025-39.
• 2013
  Jordi E, Heiman M, Marion-Poll L, Guermonprez P, Cheng SK, Nairn AC, Greengard P, Girault JA, Differential effects of cocaine on histone posttranslational modifications in identified populations of striatal neurons., Proc Natl Acad Sci U S A 2013 Jun; 110(23): 9511-6.
• 2013
  Guermonprez P, Helft J, Claser C, Deroubaix S, Karanje H, Gazumyan A, Darasse-Jèze G, Telerman SB, Breton G, Schreiber HA, Frias-Staheli N, Billerbeck E, Dorner M, Rice CM, Ploss A, Klein F, Swiecki M, Colonna M, Kamphorst AO, Meredith M, Niec R, Takacs C, Mikhail F, Hari A, Bosque D, Eisenreich T, Merad M, Shi Y, Ginhoux F, Rénia L, Urban BC, Nussenzweig MC, Inflammatory Flt3l is essential to mobilize dendritic cells and for T cell responses during Plasmodium infection., Nat Med 2013 Jun; 19(6): 730-8.
• 2012
  Helft J, Manicassamy B, Guermonprez P, Hashimoto D, Silvin A, Agudo J, Brown BD, Schmolke M, Miller JC, Leboeuf M, Murphy KM, García-Sastre A, Merad M, Cross-presenting CD103+ dendritic cells are protected from influenza virus infection., J Clin Invest 2012 Nov; 122(11): 4037-47.
• 2012
  Meredith MM, Liu K, Kamphorst AO, Idoyaga J, Yamane A, Guermonprez P, Rihn S, Yao KH, Silva IT, Oliveira TY, Skokos D, Casellas R, Nussenzweig MC, Zinc finger transcription factor zDC is a negative regulator required to prevent activation of classical dendritic cells in the steady state., J Exp Med 2012 Aug; 209(9): 1583-93.
• 2012
  Meredith MM, Liu K, Darrasse-Jeze G, Kamphorst AO, Schreiber HA, Guermonprez P, Idoyaga J, Cheong C, Yao KH, Niec RE, Nussenzweig MC, Expression of the zinc finger transcription factor zDC (Zbtb46, Btbd4) defines the classical dendritic cell lineage., J Exp Med 2012 Jun; 209(6): 1153-65.
• 2010
  Kamphorst AO, Guermonprez P, Dudziak D, Nussenzweig MC, Route of antigen uptake differentially impacts presentation by dendritic cells and activated monocytes., J Immunol 2010 Sep; 185(6): 3426-35.
• 2010
  Savina A, Vargas P, Guermonprez P, Lennon AM, Amigorena S, Measuring pH, ROS production, maturation, and degradation in dendritic cell phagosomes using cytofluorometry-based assays., Methods Mol Biol 2010 ; 595(): 383-402.
• 2009
  Bougnères L, Helft J, Tiwari S, Vargas P, Chang BH, Chan L, Campisi L, Lauvau G, Hugues S, Kumar P, Kamphorst AO, Dumenil AM, Nussenzweig M, MacMicking JD, Amigorena S, Guermonprez P, A role for lipid bodies in the cross-presentation of phagocytosed antigens by MHC class I in dendritic cells., Immunity 2009 Aug; 31(2): 232-44.
• 2009
  Saveanu L, Carroll O, Weimershaus M, Guermonprez P, Firat E, Lindo V, Greer F, Davoust J, Kratzer R, Keller SR, Niedermann G, van Endert P, IRAP identifies an endosomal compartment required for MHC class I cross-presentation., Science 2009 Jul; 325(5937): 213-7.
• 2009
  Liu K, Victora GD, Schwickert TA, Guermonprez P, Meredith MM, Yao K, Chu FF, Randolph GJ, Rudensky AY, Nussenzweig M, In vivo analysis of dendritic cell development and homeostasis., Science 2009 Apr; 324(5925): 392-7.
• 2008
  Waskow C, Liu K, Darrasse-Jèze G, Guermonprez P, Ginhoux F, Merad M, Shengelia T, Yao K, Nussenzweig M, The receptor tyrosine kinase Flt3 is required for dendritic cell development in peripheral lymphoid tissues., Nat Immunol 2008 Jun; 9(6): 676-83.
• 2008
  Tagliani E, Guermonprez P, Sepúlveda J, López-Bravo M, Ardavín C, Amigorena S, Benvenuti F, Burrone OR, Selection of an antibody library identifies a pathway to induce immunity by targeting CD36 on steady-state CD8 alpha+ dendritic cells., J Immunol 2008 Mar; 180(5): 3201-9.
• 2008
  Beauvillain C, Donnou S, Jarry U, Scotet M, Gascan H, Delneste Y, Guermonprez P, Jeannin P, Couez D, Neonatal and adult microglia cross-present exogenous antigens., Glia 2008 Jan; 56(1): 69-77.
• 2007
  Beauvillain C, Delneste Y, Scotet M, Peres A, Gascan H, Guermonprez P, Barnaba V, Jeannin P, Neutrophils efficiently cross-prime naive T cells in vivo., Blood 2007 Oct; 110(8): 2965-73.
• 2007
  Vascotto F, Le Roux D, Lankar D, Faure-André G, Vargas P, Guermonprez P, Lennon-Duménil AM, Antigen presentation by B lymphocytes: how receptor signaling directs membrane trafficking., Curr Opin Immunol 2007 Feb; 19(1): 93-8.
• 2006
  Savina A, Jancic C, Hugues S, Guermonprez P, Vargas P, Moura IC, Lennon-Duménil AM, Seabra MC, Raposo G, Amigorena S, NOX2 controls phagosomal pH to regulate antigen processing during crosspresentation by dendritic cells., Cell 2006 Jul; 126(1): 205-18.
• 2005
  Guermonprez P, Amigorena S, Pathways for antigen cross presentation., Springer Semin Immunopathol 2005 Jan; 26(3): 257-71.
• 2004
  Pascutti MF, Pitashny M, Nocito AL, Guermonprez P, Amigorena S, Wietzerbin J, Serra E, Bottasso O, Revelli S, Benznidazole, a drug used in Chagas’ disease, ameliorates LPS-induced inflammatory response in mice., Life Sci 2004 Dec; 76(6): 685-97.
• 2004
  Gil-Torregrosa BC, Lennon-Duménil AM, Kessler B, Guermonprez P, Ploegh HL, Fruci D, van Endert P, Amigorena S, Control of cross-presentation during dendritic cell maturation., Eur J Immunol 2004 Feb; 34(2): 398-407.
• 2003
  Guermonprez P, Saveanu L, Kleijmeer M, Davoust J, Van Endert P, Amigorena S, ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells., Nature 2003 Sep; 425(6956): 397-402.
• 2002
  Guermonprez P, Fayolle C, Rojas MJ, Rescigno M, Ladant D, Leclerc C, In vivo receptor-mediated delivery of a recombinant invasive bacterial toxoid to CD11c + CD8 alpha -CD11bhigh dendritic cells., Eur J Immunol 2002 Nov; 32(11): 3071-81.
• 2002
  Jiao X, Lo-Man R, Guermonprez P, Fiette L, Dériaud E, Burgaud S, Gicquel B, Winter N, Leclerc C, Dendritic cells are host cells for mycobacteria in vivo that trigger innate and acquired immunity., J Immunol 2002 Feb; 168(3): 1294-301.
• 2002
  Guermonprez P, Valladeau J, Zitvogel L, Théry C, Amigorena S, Antigen presentation and T cell stimulation by dendritic cells., Annu Rev Immunol 2002 ; 20(): 621-67.
• 2001
  Guermonprez P, Khelef N, Blouin E, Rieu P, Ricciardi-Castagnoli P, Guiso N, Ladant D, Leclerc C, The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18)., J Exp Med 2001 May; 193(9): 1035-44.
• 2000
  Himmelrich H, Lo-Man R, Winter N, Guermonprez P, Sedlik C, Rojas M, Monnaie D, Gheorghiu M, Lagranderie M, Hofnung M, Gicquel B, Clément JM, Leclerc C, Immune responses induced by recombinant BCG strains according to level of production of a foreign antigen: malE., Vaccine 2000 Jun; 18(24): 2636-47.
• 2000
  Guermonprez P, Fayolle C, Karimova G, Ullmann A, Leclerc C, Ladant D, Bordetella pertussis adenylate cyclase toxin: a vehicle to deliver CD8-positive T-cell epitopes into antigen-presenting cells., Methods Enzymol 2000 ; 326(): 527-42.
• 2000
  Osicka R, Osicková A, Basar T, Guermonprez P, Rojas M, Leclerc C, Sebo P, Delivery of CD8(+) T-cell epitopes into major histocompatibility complex class I antigen presentation pathway by Bordetella pertussis adenylate cyclase: delineation of cell invasive structures and permissive insertion sites., Infect Immun 2000 Jan; 68(1): 247-56.
• 1999
  Guermonprez P, Lo-Man R, Sedlik C, Rojas MJ, Poljak RJ, Leclerc C, mAb against hen egg-white lysozyme regulate its presentation to CD4(+) T cells., Int Immunol 1999 Nov; 11(11): 1863-72.
• 1999
  Guermonprez P, Ladant D, Karimova G, Ullmann A, Leclerc C, Direct delivery of the Bordetella pertussis adenylate cyclase toxin to the MHC class I antigen presentation pathway., J Immunol 1999 Feb; 162(4): 1910-6.
• 1998
  Guermonprez P, England P, Bedouelle H, Leclerc C, The rate of dissociation between antibody and antigen determines the efficiency of antibody-mediated antigen presentation to T cells., J Immunol 1998 Nov; 161(9): 4542-8.