Présentation
Clostridium difficile is increasingly associated with infections in hospitals and in the community, and hypervirulent types are emerging. Six research groups from 5 countries undertook this project, aiming to use genomic approaches to study C. difficile types with increased virulence and to analyze the presence of known and new virulence factors, regulation of their expression and genomic heterogeneity. The expected results will be valuable for recognizing, monitoring and diagnosing virulent types, improved prevention, and better treatment.