ERC-2017-COG_BinD – Mitotic Bookmarking, Stem Cells and early Development
The goal of this project is to deliver a new theoretical framework to understand how transcription factors (TFs) sustain cell identity during developmental processes. Recognised as key drivers of cell fate acquisition, TFs are […]
Inheritance of the pluripotency network’s activity
The preservation of pluripotency throughout cell division – self-renewal -, is strictly dependent on the highly efficient action of the pluripotency gene regulatory network. However, how TFs cope with replication and mitosis, two major […]
2019CTCF confers local nucleosome resiliency after DNA replication and during mitosis, Elife 2019 Oct;8.
2019Transcription factor activity and nucleosome organization in mitosis, Genome Res. 2019 Jan;.
2017Mitotic bookmarking in development and stem cells, Development 2017 10;144(20):3633-3645.
2017Esrrb, an estrogen-related receptor involved in early development, pluripotency, and reprogramming, FEBS Lett. 2018 03;592(6):852-877.
2017The Epigenetic Paradox of Pluripotent ES Cells, J. Mol. Biol. 2017 05;429(10):1476-1503.
2016Mitotic binding of Esrrb marks key regulatory regions of the pluripotency network, Nat. Cell Biol. 2016 Oct;.