Cours
Artificial Intelligence (AI) in Structural Biology hands-on workshop
Part 1. Critical use of AI for 3D structure prediction Instructors: Benjamin Bardiaux (Permanent researcher in the Bacterial Transmembrane Systems Unit at Institut Pasteur) & Ludovic Sauguet (Research director in the Architecture & Dynamics […]
Artificial Intelligence (AI) in Genomics hands-on workshop
Part 1. Fine-tuning biological LLMs for functional classification Intructor: Ernest Mordret (postdoctoral researcher at the Institut Pasteur) Large Language Models (LLMs) are revolutionizing biology! They capture intricate patterns within DNA and protein sequences through […]
AI for Life Sciences Theoretical Workshop for Pasteur PhD students
In the frame of Pasteur 2030 strategic plan which aims to advance expertise in artificial intelligence (AI) in biological research and develop a dedicated pathway to support the autonomy and growth of young scientists, […]
Projets Transversaux
Projets
Logiciel
Outils
Anciennes Équipes
CV
Professional experience
- 2021-Present: Institut Pasteur, Group Leader
- 2018-Present: Institut Pasteur and CNRS, Chargé de recherche de classe normal
- 2013-2018: University of Cambridge, Postdoc – Vendruscolo group
- 2014-2016: University of Washington, Consultant
- 2010-2013: University of California San Francisco, Postdoc – Sali group
Education
- June 2019: Sorbonne Université, HDR (thesis available here)
- 2006-2010: ETH Zurich, Ph.D. – Parrinello Group
- 1998-2004: Universitá degli Studi di Milano – M.Sc. in Theoretical Physics
Publications
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2025Irreversible furin cleavage site exposure renders immature tick-borne flaviviruses fully infectious., Nat Commun 2025 Aug; 16(1): 7491.
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2024Identifying small-molecules binding sites in RNA conformational ensembles with SHAMAN., Nat Commun 2024 Jul; 15(1): 5725.
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2023Genotype and Phenotype Characterization of Rhinolophus sp. Sarbecoviruses from Vietnam: Implications for Coronavirus Emergence., Viruses 2023 Sep; 15(9): .
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2023Virus Pop-Expanding Viral Databases by Protein Sequence Simulation., Viruses 2023 May; 15(6): .
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2023SARS-CoV-2-related bat virus behavior in human-relevant models sheds light on the origin of COVID-19., EMBO Rep 2023 Apr; 24(4): e56055.
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2022Determination of the structure and dynamics of the fuzzy coat of an amyloid fibril of IAPP using cryo-electron microscopy, bioRxiv 2022 10.1101/2022.05.29.493873.
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2022HARIBOSS: a curated database of RNA-small molecules structures to aid rational drug design, bioRxiv (2022) 10.1101/2022.05.17.492306.
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2022Describing Inhibitor Specificity for the Amino Acid Transporter LAT1 from Metainference Simulations, bioRxiv (2022) 10.1101/2022.05.03.490502.
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2022Artificial Intelligence: Exploring the conformational diversity of proteins, eLife 2022;11:e78549.
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2022Bat coronaviruses related to SARS-CoV-2 and infectious for human cells., Nature 2022 Apr; 604(7905): 330-336.
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