Host genetic susceptibility to Zika virus
Zika virus is an arbovirus responsible for recent epidemics in Polynesia and in the Americas. Clinical descriptions range from mild flu-like syndromes to rare but severe neurological complications such as Guillain-Barré syndrome and encephalitis […]
Understanding protective humoral immunity in asymptomatic dengue-infected individuals
Dengue is caused by dengue virus (DENV), a virus which can be transmitted by Aedes mosquitos. Half of the world’s population live in areas where the mosquito and the virus are circulating. Infection by […]
Pasteur International Center for Research on Emerging Infectious Diseases
We established an Emerging Infectious Disease Research Center in Southeast Asia and West/Central Africa with an inter-continental one-health approach designed to improve the capacity to respond rapidly and effectively to outbreaks. We built on […]
Pathogenicity and resistance to Rift Valley Fever virus.
Rift Valley fever (RVF) is a an arthropod-borne emerging viral disease that primarily affects domesticated animals (such as cattle, sheep and goats) and humans, with recent outbreaks in sub-Saharan Africa, Madagascar, and the Arabian […]
Biological study of secreted dengue virus nonstructural protein NS1 Flavivirus NS1 is involved in the intracellular stages of virus replication. It also circulates in the extracellular medium although its related function remains unknown. We […]
2020Genetic dissection of Rift Valley fever pathogenesis: Rvfs2 locus on mouse chromosome 11 enables survival to early-onset hepatitis., Sci Rep 2020 May; 10(1): 8734.
2020Genetic Diversity of Collaborative Cross Mice Controls Viral Replication, Clinical Severity, and Brain Pathology Induced by Zika Virus Infection, Independently of Oas1b., J Virol 2020 01; 94(3): .
2015The flavivirus NS1 protein’s mysteries unveiled?: (Comment on DOI 10.1002/bies.201400182), Bioessays 2015 May;37(5):472.
2014The Rift Valley fever accessory proteins NSm and P78/NSm-GN are distinct determinants of virus propagation in vertebrate and invertebrate hosts, Emerg Microbes Infect 2014 Oct;3(10):e71.
2013Role of the cytosolic tails of Rift Valley fever virus envelope glycoproteins in viral morphogenesis, Virology 2014 Jan;448:1-14.
2006Evaluation of an enzyme immunoassay for detection of dengue virus NS1 antigen in human serum, Clin. Vaccine Immunol. 2006 Nov;13(11):1185-9.
2005The secreted form of dengue virus nonstructural protein NS1 is endocytosed by hepatocytes and accumulates in late endosomes: implications for viral infectivity, J. Virol. 2005 Sep;79(17):11403-11.
2002Enzyme-linked immunosorbent assay specific to Dengue virus type 1 nonstructural protein NS1 reveals circulation of the antigen in the blood during the acute phase of disease in patients experiencing primary or secondary infections, J. Clin. Microbiol. 2002 Feb;40(2):376-81.