Laurence Mulard

Synthetic carbohydrate-based conjugates as Shigella vaccine components: design, synthesis, selection and process validation

Sitting at the frontier between the fields of Chemistry, Glycosciences, and Vaccinology, FlexBiVac is a multidisciplinary project aimed at demonstrating the proof of concept for a new generation of polysaccharide-based multivalent vaccines.  The concept […]

At the forefront of the rising fields of Chemical and Synthetic Biology, CarbUniVax is a multidisciplinary project sitting at the frontier between Glycosciences and Vaccinology. A multidisciplinary strategy is proposed that challenges ambitious goals […]

Synthetic peptides and conjugates thereof as potential antivirals (col. H. Lortat-Jacob (CEA, Grenoble), D. Bonnaffé (ICMMO, Orsay) A bi-substrate synthetic glycopeptide resulting from the covalent linkage between a CD4 peptide mimetic and a heparan […]

  Synthetic oligosaccharides are designed and used to identify immunodominant epitopes of bacterial polysaccharide antigens. Conjugates of the most promising oligosaccharides are developed as potential  vaccines. Focus is on diarrheal diseases. Shigellosis – bacillary […]