Adult neurogenesis and brain plasticity
The phenomenon of neurogenesis in adult animals, which has therapeutic potential in treating neurodegenerative diseases, leads to several questions: What controls the pattern of connections formed by new cells? How is the stability of […]
Role of Neuroinflammation in Adult Neurogenesis
Neuroinflammation, a specialized immune response that takes place in the central nervous system, has been linked to neurodegenerative diseases. Also, it has been demonstrated to affect important processes in the brain, such […]
Functional consequences of congenital cytomegalovirus infection on the central nervous system
Human cytomegalovirus (CMV) is the first cause of congenital malformation resulting from viral infection, and the leading cause of mental retardation and hearing loss. We are assessing the impact of congenital CMV infection on […]
OLFACTORY MEANS USEFUL IN THE DIAGNOSIS AND TREATMENT OF MOOD DEPRESSION
The application relates to the measure of olfactory discrimination capacity in subjects affected by a psychiatric disorder or disease involving mood disturbance, more particularly mood depression. The application provides means that are especially adapted […]
2019Long-term outcome in neuroZika: When biological diagnosis matters, Neurology 2019 Apr;.
2019Assessing Olfaction Using Ultrasonic Vocalization Recordings in Mouse Pups with a Sono-olfactometer, Bio-protocol 9(4): e3170. DOI:10.21769/BioProtoc.3170..
2018Congenital Cytomegalovirus Infection Alters Olfaction Before Hearing Deterioration In Mice, J. Neurosci. 2018 Dec;38(49):10424-10437.
2017Sensory deprivation increases phagocytosis of adult-born neurons by activated microglia in the olfactory bulb., Brain Behav Immun. 2017 Feb;60:38-43. .
2017Loss-of-function of PTPR γ and ζ, observed in sporadic schizophrenia, causes brain region-specific deregulation of monoamine levels and altered behavior in mice, Psychopharmacology (Berl). 2017 Feb;234(4):575-587. .
2016Anxiety- and Depression-Like States Lead to Pronounced Olfactory Deficits and Impaired Adult Neurogenesis in Mice, J. Neurosci. 2016 Jan;36(2):518-31.
2014Adult neurogenesis restores dopaminergic neuronal loss in the olfactory bulb, J. Neurosci. 2014 Oct;34(43):14430-42.
2013Connective tissue growth factor regulates interneuron survival and information processing in the olfactory bulb, Neuron 2013 Sep;79(6):1136-51.
2012Early activation of microglia triggers long-lasting impairment of adult neurogenesis in the olfactory bulb, J. Neurosci. 2012 Mar;32(11):3652-64.
2011Inflammation-induced subventricular zone dysfunction leads to olfactory deficits in a targeted mouse model of multiple sclerosis, J. Clin. Invest. 2011 Dec;121(12):4722-34.
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