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Marie-Elisabeth Bougnoux, obtained both her MD (1985), and her PhD (1999) at University Paris-Descartes Medical School where she is currently Associate-Professor of Parasitology-Mycology and Head of the Mycology-Parasitology laboratory of Necker Hospital, Paris (Fr.), a major referral center for immunocompromised patients, both adults and children. She is member of the Research Group “Unité Biologie et Pathogénicité Fongiques” since 2000. ME Bougnoux has focused her research on the biological and genetics/genomics aspects of Candida albicans. Specifically, she tries to decipher the complex relationships that C. albicans establishes with human hosts particularly when it switches from a commensal to a pathogen state causing severe infections with a high mortality rate. By combining her findings with detailed epidemiological and clinical observations in patients she aims to discover new therapeutic avenues and significantly change candidiasis outcome.
Publications
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2022Fungal infections in mechanically ventilated patients with COVID-19 during the first wave: the French multicentre MYCOVID study., Lancet Respir Med 2022 02; 10(2): 180-190.
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2021Regulators of commensal and pathogenic life-styles of an opportunistic fungus-Candida albicans., Yeast 2021 04; 38(4): 243-250.
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2021ATP released by Candida albicans is associated with reduced skin infectivity., J Invest Dermatol 2021 Mar; (): .
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2020A conserved regulator controls asexual sporulation in the fungal pathogen Candida albicans., Nat Commun 2020 12; 11(1): 6224.
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2020The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives., FEMS Microbiol Rev 2020 Nov; (): .
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2020Candida albicans and Candida dubliniensis Show Different Trailing Effect Patterns When Exposed to Echinocandins and Azoles., Front Microbiol 2020 ; 11(): 1286.
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2020Tracing the Origin of Invasive Fungal Infections., Trends Microbiol 2020 04; 28(4): 240-242.
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2020Identification and Characterization of Mediators of Fluconazole Tolerance in Candida albicans., Front Microbiol 2020 ; 11(): 591140.
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2019Within-Host Genomic Diversity of Candida albicans in Healthy Carriers, Sci Rep 2019 Feb;9(1):2563.
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2018Clinical Impact of Antifungal Susceptibility, Biofilm Formation and Mannoside Expression of Yeasts on the Outcome of Invasive Candidiasis in ICU: An Ancillary Study on the Prospective AmarCAND2 Cohort, Front Microbiol 2018;9:2907.
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