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CV
Marie-Elisabeth Bougnoux, obtained both her MD (1985), and her PhD (1999) at University Paris-Descartes Medical School where she is currently Associate-Professor of Parasitology-Mycology and Head of the Mycology-Parasitology laboratory of Necker Hospital, Paris (Fr.), a major referral center for immunocompromised patients, both adults and children. She is member of the Research Group “Unité Biologie et Pathogénicité Fongiques” since 2000. ME Bougnoux has focused her research on the biological and genetics/genomics aspects of Candida albicans. Specifically, she tries to decipher the complex relationships that C. albicans establishes with human hosts particularly when it switches from a commensal to a pathogen state causing severe infections with a high mortality rate. By combining her findings with detailed epidemiological and clinical observations in patients she aims to discover new therapeutic avenues and significantly change candidiasis outcome.
Publications
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2024A gain-of-function mutation in zinc cluster transcription factor Rob1 Drives Candida albicans adaptive growth in the cystic fibrosis lung environment., PLoS Pathog 2024 Apr; 20(4): e1012154.
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2024Features of cryptococcosis among 652 HIV-seronegative individuals in France: a cross-sectional observational study (2005-2020)., Clin Microbiol Infect 2024 Mar; (): .
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2024Perturbation and resilience of the gut microbiome up to 3 months after β-lactams exposure in healthy volunteers suggest an important role of microbial β-lactamases., Microbiome 2024 Mar; 12(1): 50.
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2023Unveiling Candida albicans intestinal carriage in healthy volunteers: the role of micro- and mycobiota, diet, host genetics and immune response., Gut Microbes 2023 Dec; 15(2): 2287618.
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2023The pathogenic and colonization potential of Candida africana., Microbes Infect 2023 Sep; (): 105230.
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2023Invasive fungal diseases in patients with autoimmune diseases: a case series from the French RESSIF network., RMD Open 2023 Aug; 9(3): .
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2022Primary Invasive Cutaneous Fusariosis in Patients with STAT3 Hyper-IgE Syndrome., J Clin Immunol 2022 Dec; (): .
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2022Fungal infections in mechanically ventilated patients with COVID-19 during the first wave: the French multicentre MYCOVID study., Lancet Respir Med 2022 02; 10(2): 180-190.
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2021Regulators of commensal and pathogenic life-styles of an opportunistic fungus-Candida albicans., Yeast 2021 04; 38(4): 243-250.
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2021ATP released by Candida albicans is associated with reduced skin infectivity., J Invest Dermatol 2021 Mar; (): .
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