Synthetic carbohydrate-based conjugates as Shigella vaccine components: design, synthesis, selection and process validation
Think tank: Mucosal Immunology
The Think tank Mucosal Immunology gathers several research units form the departments of immunology, microbiology, cellular biology and epidemilogy and infection, as well as from the Institut Imagine (Necker) and Hôpital Paul Brousse. It […]
A synthetic carbohydrate-based conjugate vaccine ready for a clinical trial
Sitting at the frontier between the fields of Chemistry, Glycosciences, and Vaccinology, FlexBiVac is a multidisciplinary project aimed at demonstrating the proof of concept for a new generation of polysaccharide-based multivalent vaccines. The concept […]
GPF Vaccinology Call 1: Open call for new ideas for cutting-edge science investigations in vaccinology.
The purpose of this call for ideas is to solicit community input for original, cutting-edge science investigations that are consistent with the Institut Pasteur’s new development strategy in vaccinology. The “Open Pasteur vaccine challenge” […]
GPF Vaccinology Call 2: Accelerating Preclinical Development of Vaccine Candidates
With the second call, the GPF Vaccinology aims at identifying ongoing preclinical projects aiming to develop vaccine candidates at Institut Pasteur, including the International Network. The objective of the GPF call is to help […]
Comics on vaccination
The Center for Translational Science, the Center Medical Institut Pasteur (CMIP) and the major federating program (GPF) vaccinology welcome for one year a science illustrator, Celia Ducaju, in partnership with the Ecole Estienne School […]
At the forefront of the rising fields of Chemical and Synthetic Biology, CarbUniVax is a multidisciplinary project sitting at the frontier between Glycosciences and Vaccinology. A multidisciplinary strategy is proposed that challenges ambitious goals […]
2015Draft genomes of Shigella strains used by the STOPENTERICS consortium, Gut Pathog 2015;7:14.
2015Editorial, Semin. Immunol. 2015 Mar;27(2):73-4.
2015Pathogen manipulation of B cells: the best defence is a good offence, Nat. Rev. Microbiol. 2015 Mar;13(3):173-84.
2014Non-stoichiometric O-acetylation of Shigella flexneri 2a O-specific polysaccharide: synthesis and antigenicity, Org. Biomol. Chem. 2014 Jun;12(24):4218-32.
2014B lymphocytes undergo TLR2-dependent apoptosis upon Shigella infection, J. Exp. Med. 2014 Jun;211(6):1215-29.
2014New insights into the crosstalk between Shigella and T lymphocytes, Trends Microbiol. 2014 Apr;22(4):192-8.
2011Dynamic aspects of antibody:oligosaccharide complexes characterized by molecular dynamics simulations and saturation transfer difference nuclear magnetic resonance, Glycobiology 2011 Dec;21(12):1570-9.
2011The Shigella flexneri type three secretion system effector IpgD inhibits T cell migration by manipulating host phosphoinositide metabolism, Cell Host Microbe 2011 Apr;9(4):263-72.
2011Monitoring Shigella flexneri vacuolar escape by flow cytometry, Virulence 2011 Jan-Feb;2(1):54-7.
2010Effects of backbone substitutions on the conformational behavior of Shigella flexneri O-antigens: implications for vaccine strategy, Glycobiology 2011 Jan;21(1):109-21.
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