Présentation
Abstract :
The infection by the parasite Cryptosporidium is a leading cause of child mortality, no vaccine is available and the current drug treatment against this diarrheal pathogen is inefficient. The parasite infects the epithelial cells of the small intestine in which it replicates intracellularly. These events require extensive modifications of the host cell that remain largely unknown at the molecular level. We recently showed that parasite secreted proteins play an important role in these processes, however, our knowledge remains limited. Our lab focuses on the identification and characterization of these parasite secreted effectors and their impact on the infected host cell.
https://www.unige.ch/medecine/mimo/en/groupes/amandine-guerin