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Présentation
Anciennes Équipes
CV
06/2021 – present
Head of the ‘Parasite RNA Biology’ Group at the Institut Pasteur, France
04/2016 – 05/2021
Post-doctoral researcher, ‘Biology of Host-Parasite Interactions Unit’, Institut Pasteur, France
“The role of RNA modifications in post-transcriptional gene regulation of the human malaria parasite, Plasmodium falciparum”
09/2013 – 02/2016:
Ph.D., Red Sea Research Center, King Abdullah University of Science and Technology, Saudi Arabia.
“The genome of Aiptasia and the role of microRNAs in cnidarian-dinoflagellate endosymbiosis”, supervised by Dr. Christian R. Voolstra
09/2012 – 08/2013
MSc., Red Sea Research Center, King Abdullah University of Science and Technology, Saudi Arabia
“The microRNA repertoire of Symbiodinium, the dinoflagellate symbiont of reef-building corals”, supervised by Dr. Christian R. Voolstra
09/2009 – 08/2012
BSc., University of Tübingen, Germany.
“Population structure, growth and production of a recent brachiopod from the Chilean fjord region”, supervised by Dr. Jürgen Laudien and Dr. Nico K. Michiels
Publications
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2023Cohesin contributes to transcriptional repression of stage-specific genes in the human malaria parasite., EMBO Rep 2023 Aug; (): e57090.
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2023Discovery of RUF6 ncRNA-interacting proteins involved in P. falciparum immune evasion., Life Sci Alliance 2023 Jan; 6(1): .
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2021Malaria Parasite Stress Tolerance Is Regulated by DNMT2-Mediated tRNA Cytosine Methylation, mBio. 2021 Nov-Dec; 12(6): e02558-21.
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2021Functional Characterization of the m6A-Dependent Translational Modulator PfYTH.2 in the Human Malaria Parasite., mBio 2021 04; 12(2): .
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2020Exploring the virulence gene interactome with CRISPR/dCas9 in the human malaria parasite., Mol Syst Biol 2020 08; 16(8): e9569.
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2020Rapid activation of distinct members of multigene families in Plasmodium spp., Commun Biol 2020 07; 3(1): 351.
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2019A Novel Tool for the Generation of Conditional Knockouts To Study Gene Function across the Plasmodium falciparum Life Cycle, MBio 2019 Sep;10(5).
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2019Transcriptome-wide dynamics of extensive m6A mRNA methylation during Plasmodium falciparum blood-stage development., Nat Microbiol 2019 12; 4(12): 2246-2259.
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2019CRISPR in Parasitology: Not Exactly Cut and Dried!, Trends Parasitol 2019 06; 35(6): 409-422.
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2018Disruption of the RNA exosome reveals the hidden face of the malaria parasite transcriptome., RNA Biol 2018 ; 15(9): 1206-1214.
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