Présentation
June 10th, 2025 – Institut Pasteur Amphi Duclaux
The Structural Biology and Chemistry Department together with the Center for Technological Resources and Research C2RT will run the “ICE-Day” event from 9am to 6pm in the Duclaux lecture hall.
This day will gather cryo-electron microscopy (cryo-EM) specialists from the Paris area to exchange on results obtained at local and external facilities. The keynote speaker at the event will be Kevin Macé from the Insititut de Génétique et Développement of Rennes. Representatives of 3 French cryo-EM facilities, including the Pasteur NanoImaging Center, will present recent updates and developments.
The event is free but prior registration is required. Registration will be open until May 30th:
https://www.eventbrite.fr/e/iceday-10-june-2025-tickets-1317428697699?aff=oddtdtcreator
Program :
9:00-9:10 Welcome
9:10-10:00 Keynote speaker – Kevin Macé (Institut de Génétique & Développement de Rennes ) “From structure to mechanism: decoding pilus biogenesis of type IV secretion systems”
10:00-10:20 Chiara Rapisarda (Sanofi) “Optimizing antibody Fab scaffolds for Cryo-EM”
10:20-10:40 Clément Madru (Ecole Polytechnique) “When ribosomes sleep: structural insights into translational hibernation in Archaea”
10:40-11:00 Nathalie Dautin (IBPC) “Haem import by Haemophilus influenzae”
11:00-11:30 Coffee break
11:30-11:50 Marie Imbert (Institut Pasteur) “Structural snapshots of D-loop formation in Archaea revealed by Cryo-EM”
11:50-12:10 Laurie Lannes (Institut Curie) “Effect of the phase 3 drug candidate Aficamten on the conformational states of beta-cardiac myosin2”
12:10-12:50 Thibaud Dieudonné (I2BC) “Cryo-EM@Paris-Saclay: Benchmarking the new microscopes with a membrane protein”
12:50-14:00 Lunch @ the module
14:00-14:20 Sophia Missoury (Institut Pasteur) “Strategies to stabilize DNA Repair Complexes: a highly versatile machinery”
14:20-14:40 Johannes Groen (Institut Pasteur) “Multimodal and correlative imaging approaches to study early stages of SARS-CoV 2 infection”
14:40-15:00 Antonio El Helou (Institut Pasteur) “In Situ Cryo-Electron Tomography of Hair Cells in Mouse Cochlea”
15:00-15:20 Marvin Albert (Institut Pasteur) “Analysis tools for CLEM and morphometry to study Type Three Secretion System mediated Shigella host cell entry”
15:20-16:00 Coffee break
16:00-16:20 Dhirendra Singh (ThermoFisher) “Introduction to the new Krios 5”
16:20-16:40 Eaazhisai Kandiah (ESRF) ” Cryo-EM at ESRF for structural biology research”
16:40-17:00 Matthijn Vos (Institut Pasteur) – TBA
17:00-17:20 Pierre Legrand (Soleil) “First 6 months of operation on POLARIS @ SOLEIL”
17:20-17:30 Concluding remarks
17:30 : Wine and cheese