Timeline

Ariel MECHALY
Research Engineer
01 May 2021
publication

A High-Affinity Calmodulin-Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells.

Read more
13 Jan 2021
publication

Molecular basis of the interaction of the human tyrosine phosphatase PTPN3 with the hepatitis B virus core protein.

Read more
06 Nov 2020
publication

Deciphering the Unexpected Binding Capacity of the Third PDZ Domain of Whirlin to Various Cochlear Hair Cell Partners.

Read more
06 Jul 2020
publication

Evolution of abiotic cubane chemistries in a nucleic acid aptamer allows selective recognition of a malaria biomarker.

Read more
11 Mar 2020
publication

An asymmetric sheath controls flagellar supercoiling and motility in the leptospira spirochete.

Read more
05 Dec 2019
publication

High-Throughput Crystallization Pipeline at the Crystallography Core Facility of the Institut Pasteur

Read more
31 Jul 2019
publication

Directly Sequenced Genomes of Contemporary Strains of Syphilis Reveal Recombination-Driven Diversity in Genes Encoding Predicted Surface-Exposed Antigens

Read more
17 Oct 2018
publication

Evidence of Alternative Splicing as a Regulatory Mechanism for Kissr2 in Pejerrey Fish

Read more
04 Aug 2018
publication

Conformational plasticity of the response regulator CpxR, a key player in Gammaproteobacteria virulence and drug-resistance

Read more
15 Jul 2018
publication

Structural insights into the signalling mechanisms of two-component systems

Read more
23 Feb 2018
publication

Lvr, a Signaling System That Controls Global Gene Regulation and Virulence in Pathogenic

Read more
25 May 2017
publication

Structural Coupling between Autokinase and Phosphotransferase Reactions in a Bacterial Histidine Kinase

Read more
21 Feb 2017
publication

Crystallization of FcpA from Leptospira, a novel flagellar protein that is essential for pathogenesis

Read more
12 Dec 2016
publication

Regulation of signaling directionality revealed by 3D snapshots of a kinase:regulator complex in action

Read more
18 Feb 2016
publication

What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira

Read more
10 Dec 2015
publication

Structural Basis of Pullulanase Membrane Binding and Secretion Revealed by X-Ray Crystallography, Molecular Dynamics and Biochemical Analysis

Read more
11 May 2015
team

Structural Microbiology

Read more
17 Feb 2015
team

Crystallography

Read more
18 Nov 2014
publication

Allosteric activation of bacterial response regulators: the role of the cognate histidine kinase beyond phosphorylation

Read more
13 May 2014
publication

Potent and specific inhibition of glycosidases by small artificial binding proteins (affitins)

Read more
28 Jan 2014
publication

Segmental helical motions and dynamical asymmetry modulate histidine kinase autophosphorylation

Read more
21 Jun 2012
publication

Pores of the toxin FraC assemble into 2D hexagonal clusters in both crystal structures and model membranes

Read more
03 May 2012
publication

Conformational changes upon ligand binding in the essential class II fumarase Rv1098c from Mycobacterium tuberculosis

Read more
09 Feb 2011
publication

Structural insights into the oligomerization and architecture of eukaryotic membrane pore-forming toxins

Read more
21 Mar 2009
publication

Crystallization and preliminary crystallographic analysis of fragaceatoxin C, a pore-forming toxin from the sea anemone Actinia fragacea

Read more
11 Mar 2008
publication

A plate holder for non-destructive testing of mesophase crystallization assays

Read more
08 Jul 2006
publication

Crystal structure of the temperature-sensitive and allosteric-defective chaperonin GroELE461K

Read more