Timeline

Valérie Huteau

Technician

15 Jan 2023

publication

Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.

29 Aug 2022

publication

Structure-based design, synthesis and biological evaluation of a NAD+ analogue targeting Pseudomonas aeruginosa NAD kinase.

13 Mar 2020

publication

From Substrate to Fragments to Inhibitor Active In Vivo against Staphylococcus aureus.

06 Jul 2018

publication

Enzymatic synthesis of random sequences of RNA and RNA analogues by DNA polymerase theta mutants for the generation of aptamer libraries

09 Jan 2018

team

Epigenetic Chemical Biology

20 Aug 2015

project

Inhibitors of TMPK from Mycobacterium tuberculosis

03 Aug 2015

project

Inhibitors of the 2’-deoxyribonucleotide N-hydrolase DNPH1, an enzyme involved in cellular growth and angiogenesis

28 Jul 2015

project

Inhibitors of bacterial NAD kinases

26 Feb 2014

publication

Synthesis of novel 9-aryl and heteroarylpurine derivatives via copper mediated coupling reaction

06 Jun 2012

publication

Screening and in situ synthesis using crystals of a NAD kinase lead to a potent antistaphylococcal compound.

03 Aug 2008

publication

A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial

25 Apr 2008

publication

Substituted benzyl-pyrimidines targeting thymidine monophosphate kinase of Mycobacterium tuberculosis: synthesis and in vitro anti-mycobacterial activity

A little guide for advanced search:

Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.

Structure-based design, synthesis and biological evaluation of a NAD+ analogue targeting Pseudomonas aeruginosa NAD kinase.

From Substrate to Fragments to Inhibitor Active In Vivo against Staphylococcus aureus.

Enzymatic synthesis of random sequences of RNA and RNA analogues by DNA polymerase theta mutants for the generation of aptamer libraries

Epigenetic Chemical Biology

Inhibitors of TMPK from Mycobacterium tuberculosis

Inhibitors of the 2’-deoxyribonucleotide N-hydrolase DNPH1, an enzyme involved in cellular growth and angiogenesis

Inhibitors of bacterial NAD kinases

Synthesis of novel 9-aryl and heteroarylpurine derivatives via copper mediated coupling reaction

Screening and in situ synthesis using crystals of a NAD kinase lead to a potent antistaphylococcal compound.

A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial

Substituted benzyl-pyrimidines targeting thymidine monophosphate kinase of Mycobacterium tuberculosis: synthesis and in vitro anti-mycobacterial activity