Ligne de temps

Valérie Huteau
Technicien(ne)
15 janv. 2023
publication

Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria.

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29 août 2022
publication

Structure-based design, synthesis and biological evaluation of a NAD+ analogue targeting Pseudomonas aeruginosa NAD kinase.

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13 mars 2020
publication

From Substrate to Fragments to Inhibitor Active In Vivo against Staphylococcus aureus.

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06 juil. 2018
publication

Enzymatic synthesis of random sequences of RNA and RNA analogues by DNA polymerase theta mutants for the generation of aptamer libraries

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09 janv. 2018
team

Chimie Biologique Epigénétique

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20 août 2015
project

Inhibitors of TMPK from Mycobacterium tuberculosis

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03 août 2015
project

Inhibitors of the 2’-deoxyribonucleotide N-hydrolase DNPH1, an enzyme involved in cellular growth and angiogenesis

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28 juil. 2015
project

Inhibitors of bacterial NAD kinases

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26 févr. 2014
publication

Synthesis of novel 9-aryl and heteroarylpurine derivatives via copper mediated coupling reaction

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06 juin 2012
publication

Screening and in situ synthesis using crystals of a NAD kinase lead to a potent antistaphylococcal compound.

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03 août 2008
publication

A new synthetic access to furo[3,2-f]chromene analogues of an antimycobacterial

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25 avr. 2008
publication

Substituted benzyl-pyrimidines targeting thymidine monophosphate kinase of Mycobacterium tuberculosis: synthesis and in vitro anti-mycobacterial activity

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