Timeline

Guillaume Bouvier

Permanent Researcher

01 Apr 2024

publication

Mechanism of action of phthalazinone derivatives against rabies virus.

13 Sep 2022

publication

Building Protein Atomic Models from Cryo-EM Density Maps and Residue Co-Evolution.

11 Sep 2022

project

Energir: Energy dependent iron import by Gram-negative bacteria

01 Jan 2022

publication

Deciphering the Molecular Interaction Between the Adhesion G Protein-Coupled Receptor ADGRV1 and its PDZ-Containing Regulator PDZD7.

15 Dec 2021

publication

InDeep: 3D fully convolutional neural networks to assist in silico drug design on protein-protein interactions.

24 Jan 2019

patent

Docking method based on saturation transfer difference NMR data, and means for its implementation WO 2019/011987

18 Dec 2018

publication

Target engagement and binding mode of an anti-tuberculosis drug to its bacterial target deciphered in whole living cells by NMR.

16 Mar 2018

publication

Ordering Protein Contact Matrices

09 Mar 2018

project

Protein synthesis machinery of Trypanosomatid as a therapeutic target

25 Apr 2016

publication

Automated structure modeling of large protein assemblies using crosslinks as distance restraints

14 Sep 2015

publication

Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation

08 Sep 2015

publication

Improved large-scale prediction of growth inhibition patterns using the NCI60 cancer cell line panel.

31 Aug 2015

project

Binding mode of promising antituberculosis clinical compounds to their bacterial target

07 Jul 2015

project

ERC-2011-AdG BAYCELLS

07 Jul 2015

project

Bip:Bip

03 Jun 2015

publication

Temperature Accelerated Molecular Dynamics with Soft-Ratcheting Criterion Orients Enhanced Sampling by Low-Resolution Information

11 May 2015

team

Structural Bioinformatics

21 Mar 2015

publication

Identification of binding sites and favorable ligand binding moieties by virtual screening and self-organizing map analysis

26 Dec 2014

publication

An automatic tool to analyze and cluster macromolecular conformations based on self-organizing maps

27 Mar 2014

publication

Distinct docking and stabilization steps of the Pseudopilus conformational transition path suggest rotational assembly of type IV pilus-like fibers

15 Jan 2014

publication

Functional motions modulating VanA ligand binding unraveled by self-organizing maps

17 Oct 2013

publication

Stabilization of the integrase-DNA complex by Mg2+ ions and prediction of key residues for binding HIV-1 integrase inhibitors

07 Sep 2012

publication

A convective replica-exchange method for sampling new energy basins

06 Sep 2012

publication

Contact-based ligand-clustering approach for the identification of active compounds in virtual screening

12 Nov 2009

publication

Automatic clustering of docking poses in virtual screening process using self-organizing map

25 Mar 2008

publication

A little guide for advanced search:

Timeline

Mechanism of action of phthalazinone derivatives against rabies virus.

Building Protein Atomic Models from Cryo-EM Density Maps and Residue Co-Evolution.

Energir: Energy dependent iron import by Gram-negative bacteria

Deciphering the Molecular Interaction Between the Adhesion G Protein-Coupled Receptor ADGRV1 and its PDZ-Containing Regulator PDZD7.

InDeep: 3D fully convolutional neural networks to assist in silico drug design on protein-protein interactions.

Docking method based on saturation transfer difference NMR data, and means for its implementation WO 2019/011987

Target engagement and binding mode of an anti-tuberculosis drug to its bacterial target deciphered in whole living cells by NMR.

Ordering Protein Contact Matrices

Protein synthesis machinery of Trypanosomatid as a therapeutic target

Automated structure modeling of large protein assemblies using crosslinks as distance restraints

Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation

Improved large-scale prediction of growth inhibition patterns using the NCI60 cancer cell line panel.

Binding mode of promising antituberculosis clinical compounds to their bacterial target

ERC-2011-AdG BAYCELLS

Bip:Bip

Temperature Accelerated Molecular Dynamics with Soft-Ratcheting Criterion Orients Enhanced Sampling by Low-Resolution Information

Structural Bioinformatics

Identification of binding sites and favorable ligand binding moieties by virtual screening and self-organizing map analysis

An automatic tool to analyze and cluster macromolecular conformations based on self-organizing maps

Distinct docking and stabilization steps of the Pseudopilus conformational transition path suggest rotational assembly of type IV pilus-like fibers

Functional motions modulating VanA ligand binding unraveled by self-organizing maps

Stabilization of the integrase-DNA complex by Mg2+ ions and prediction of key residues for binding HIV-1 integrase inhibitors

A convective replica-exchange method for sampling new energy basins

Contact-based ligand-clustering approach for the identification of active compounds in virtual screening

Automatic clustering of docking poses in virtual screening process using self-organizing map

The key-role of tyrosine 155 in the mechanism of prion transconformation as highlighted by a study of sheep mutant peptides