Timeline

Ludovic Halby
Research Engineer
22 May 2023
publication

Plasmodium falciparum Eukaryotic Translation Initiation Factor 3 is Stabilized by Quinazoline-Quinoline Bisubstrate Inhibitors.

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17 Feb 2023
publication

Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant Plasmodium falciparum.

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11 Jan 2023
news

New publication: Hemisynthetic alkaloids derived from trilobine are antimalarials with sustained activity in multidrug-resistant Plasmodium falciparum

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01 Apr 2022
publication

Quinazoline-based analog of adenine as an antidote against MLL-rearranged leukemia cells: synthesis, inhibition assays and docking studies.

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01 Dec 2021
publication

Direct Synthesis of Allyl Amines with 2-Nitrosulfonamide Derivatives via the Tsuji-Trost Reaction.

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31 Aug 2021
publication

Synthesis and Biological Activity of a Cytostatic Inhibitor of MLLr Leukemia Targeting the DOT1L Protein

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15 Aug 2021
publication

Direct Synthesis of Allyl Amines with 2‐Nitrosulfonamide Derivatives via the Tsuji‐Trost Reaction

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22 Jul 2021
publication

Procainamide-SAHA Fused Inhibitors of hHDAC6 Tackle Multidrug-Resistant Malaria Parasites.

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18 Feb 2021
project

Epi-Med: synthesis and biological evaluation of new active molecules against MLL-rearranged leukaemia.

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18 Feb 2021
project

EpiKillMal- Use of DNA methyltransferase inhibitors to kill drug-resistant malaria parasites –

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17 Sep 2020
publication

Bisubstrate inhibitors: the promise of a selective and potent chemical inhibition of epigenetic ‘writers’

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01 Sep 2020
publication

Bisubstrate inhibitors: the promise of a selective and potent chemical inhibition of epigenetic ‘writers’.

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19 Mar 2020
publication

Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs.

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22 Jan 2020
publication

DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites.

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01 Oct 2019
publication

[Chemical targeting of DNA and histone methylation in cancer: Novelties, hopes and promises].

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24 Sep 2019
project

Targeting Malaria Epigenetics

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19 Sep 2019
publication

Espoirs et promesses de la méthylation de l’ADN et des histones comme cibles anticancéreuses

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09 Jan 2018
team

Epigenetic Chemical Biology

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