My research interests are mainly focused on the structure-function relationships of macromolecules through multidisciplinary approaches. My studies have been concentrated on crucial enzymes belonging to the nucleotide metabolism, in particular nucleoside monophosphate kinases (NMPKs) […]
Dr. Najma Rachidi is a senior Researcher and the leader of the molecular parasitology team in the PARSIG unit. Her team investigates Host-pathogen interactions to (i) understand how Leishmania survives in immune cells, which […]
SCIENTIFIC POSITIONS Head of Auditory Therapies Innovation Laboratory at the Hearing Institute (an Institut Pasteur Center), Paris Professor “Classe Exceptionnelle” at Institut Pasteur, Paris Professor Emeritus at Collège de France, Chair of Genetics […]
I was trained as a chemist and did my PhD (Paris) and post-doctoral fellowship (Brighton) in organic synthesis. He then joined the Pasteur Institute as a CNRS researcher to work on nicotinic acetylcholine receptors, […]
Circular dichroism (CD) allows the measurement of secondary and tertiary structures, the analyse of conformational changes, the kinetic of folding and the thermal and chemical stability of folding. Fluorescence spectroscopy gives access to the […]
Analytical Ultracentrifugation gives access to the mass and shape of macromolecules in solution, allowing to evaluate their oligomerization state, their stoichiometry and the equilibrium constant of assemblies. Dynamic Light Scattering (cuvette or microplaque) allows […]
Static Light Scattering allows to measure the mass and intrinsic viscosity of macromolecules Analytical Ultracentrifugation gives access to the oligomerization state and the stoichiometry of molecular assemblies
