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© Research
Publication : PLoS Biology

Using Sex to Cure the Genome

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in PLoS Biology - 17 Mar 2016

Eduardo PC Rocha

PLoS Biol 14(3): e1002417. doi:10.1371/ journal.pbio.1002417

The diversification of prokaryotes is accelerated by their ability to acquire DNA from other genomes. However, the underlying processes also facilitate genome infection by costly mobile genetic elements. The discovery that cells can uptake DNA by natural transforma- tion was instrumental to the birth of molecular biology nearly a century ago. Surprisingly, a new study shows that this mechanism could efficiently cure the genome of mobile elements acquired through previous sexual exchanges.

http://journals.plos.org/plosbiology/article?id=10.1371%2Fjournal.pbio.1002417