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© Therese Couderc, Marc Lecuit
Publication : Current opinion in virology

Sustained fecal-oral human-to-human transmission following a zoonotic event

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Current opinion in virology - 23 Nov 2016

de Graaf M, Beck R, Caccio SM, Duim B, Fraaij P, Le Guyader FS, Lecuit M, Le Pendu J, de Wit E, Schultsz C

Link to Pubmed [PMID] – 27888698

Curr Opin Virol 2016 Nov;22:1-6

Bacterial, viral and parasitic zoonotic pathogens that transmit via the fecal-oral route have a major impact on global health. However, the mechanisms underlying the emergence of such pathogens from the animal reservoir and their persistence in the human population are poorly understood. Here, we present a framework of human-to-human transmission of zoonotic pathogens that considers the factors relevant for fecal-oral human-to-human transmission route at the levels of host, pathogen, and environment. We discuss current data gaps and propose future research directions.

https://www.ncbi.nlm.nih.gov/pubmed/27888698