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© A. Chauhan, JM Ghigo, C. Beloin.
Biofilm formation by Pseudomonas aeruginosa bacteria in Central Venous Catheter. Bacteria are stained in yellow and blood cells in red.
Publication : International Journal of Medical Microbiology

Regulation of virulence gene expression in Shigella flexneri, a facultative intracellular pathogen

Team: Group: Christophe Beloin
Member: Christophe Beloin
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in International Journal of Medical Microbiology - 01 May 2001

Dorman CJ, McKenna S, Beloin C.

Link to Pubmed [PMID] – 11437343

Int J Med Microbiol. 2001 May;291(2):89-96.

Shigella flexneri and its close relatives are facultative intracellular pathogens of humans and are the etiological agents of bacillary dysentery. These bacteria secrete proteins that enable them to enter human epithelial cells via an elaborate and fascinating cell biology. This behaviour depends on a complicated regulon of virulence genes, whose expression is controlled in response to a multiplicity of environmental signals. This review describes and attempts to interpret these gene control mechanisms.