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© Research
Publication : Journal of clinical microbiology

Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates

Team: Archived: Group: Sylvain Brisse
Team: Microbial Evolutionary Genomics
Team: Environment and Infectious Risks
Member: Sylvain Brisse
Member: Laure Diancourt
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of clinical microbiology - 01 Aug 2005

Diancourt L, Passet V, Verhoef J, Grimont PA, Brisse S

Link to Pubmed [PMID] – 16081970

J. Clin. Microbiol. 2005 Aug;43(8):4178-82

A multilocus sequence typing (MLST) scheme was developed for Klebsiella pneumoniae. Sequences of seven housekeeping genes were obtained for 67 K. pneumoniae strains, including 19 ceftazidime- and ciprofloxacin-resistant isolates. Forty distinct allelic profiles were identified. MLST data were validated against ribotyping and showed high (96%) discriminatory power. The MLST approach provides unambiguous data useful for the epidemiology of K. pneumoniae isolates.