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© Research
Publication : Journal of microscopy

Microcomputer system for ion microscopy digital imaging and processing

Team: Biological Image Analysis
Member: Jean-Christophe Olivo-Marin
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of microscopy - 01 Oct 1989

Olivo JC, Kahn E, Halpern S, Briancon C, Fragu P, DiPaola R

Link to Pubmed [PMID] – 2585475

J Microsc 1989 Oct;156(Pt 1):105-14

Analytical ion microscopy is a powerful tool for biological tissue analysis as it allows direct chemical distribution imaging, even at low element concentrations. A microcomputer based digital imaging system achieving acquisition at low light level is presented. It includes a high sensitivity video camera connected to a specialized image processor subsystem. Acquired images consist of 512 x 512 pixels with 8 bits accuracy. Real-time image processing software has been implemented so that image processing may be performed on-line. Image processing software allows off-line image manipulation and correlation for biological interpretation of elemental mapping images. System capabilities are illustrated by a study of stable and radio iodine mapping in rat thyroid tissue.